A5102020990- Helicobacter pylori-related gastroenterology studies
- Geological and Geochemical Analysis
- Electrochemical Analysis and Applications
- Cancer, Hypoxia, and Metabolism
- Geochemistry and Geologic Mapping
- Antifungal resistance and susceptibility
- Bone Tissue Engineering Materials
- Mitochondrial Function and Pathology
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Reproductive tract infections research
- Diet and metabolism studies
- Pelvic floor disorders treatments
- Geochemistry and Geochronology of Asian Mineral Deposits
- Geochemistry and Elemental Analysis
- Veterinary medicine and infectious diseases
- Endometriosis Research and Treatment
- Additive Manufacturing and 3D Printing Technologies
- biodegradable polymer synthesis and properties
- Advanced Chemical Sensor Technologies
- Gynecological conditions and treatments
- Phytochemical Studies and Bioactivities
- Urinary Tract Infections Management
- Reproductive System and Pregnancy
- Biotin and Related Studies
Nanjing Medical University
2016-2025
China University of Geosciences
2016-2024
Peking University Shenzhen Hospital
2016-2024
Shenzhen Technology University
2018-2024
Hong Kong University of Science and Technology
2023-2024
University of Hong Kong
2023-2024
Hunan University of Science and Technology
2024
Nanjing University of Chinese Medicine
2024
Changzhou No.2 People's Hospital
2024
Hunan Institute of Engineering
2016-2024
Abstract Multiwall carbon nanotubes were dispersed in Nafion (MWCNTs‐NA) solution and used combination with bismuth (MWCNTs‐NA/Bi) for fabricating composite sensors to determine trace Pb(II) Cd(II) by differential pulse anodic stripping voltammetry (DPASV). The electrochemical properties of the MWCNTs‐NA/Bi composites film modified glassy electrode (GCE) evaluated. synergistic effect MWCNTs was obtained detection improved sensitivity reproducibility. Linear calibration curves ranged from...
Metasomatic alteration of fluorapatite has been reported in several iron-oxide apatite (IOA) deposits, but its effect on elemental and isotopic variations not well understood. In this study, we present integrated elemental, U-Pb, Sr, O microanalytical data fresh altered domains from the Taocun IOA deposit, Eastern China, to evaluate timing nature metasomatism effects ore-forming event. Orebodies deposit are spatially associated with a subvolcanic, intermediate intrusion, which displays zonal...
The human uterus is traditionally believed to be sterile, while the vaginal microbiota plays an important role in fending off pathogens. Emerging evidence demonstrates presence of bacteria beyond vagina. However, a microbiome-wide metagenomic analysis characterizing diverse microbial communities has been lacking.
Endometriosis (EMS) is a multifactorial disease that affects 10%-15% women of reproductive age and associated with chronic pelvic pain infertility. The pathogenesis EMS has not been consistently explained until now. In this study, we involved 36 endometriosis patients 14 control subjects who performed laparoscopic surgery due to gynecological benign tumor. samples from lower third vagina (CL), posterior vaginal fornix (CU), cervical mucus (CV), endometrium (ET) peritoneal fluid (PF), were...
Staphylococcus aureus poses a severe public health problem as one of the vital causative agents healthcare- and community-acquired infections. There is globally urgent need for new drugs with novel mode action (MoA) to combat S. biofilms persisters that tolerate antibiotic treatment. We demonstrate benzonaphthopyranone glycoside, chrysomycin A (ChryA), rapid bactericide highly active against persisters, robustly eradicates in vitro, shows sustainable killing efficacy vivo. ChryA was...
Abstract High-titanium (high-Ti, more than 1 wt % Ti) magnetite, commonly containing ilmenite exsolution, has long been attributed to an igneous origin and used as the most critical factor in previously developed discriminant diagrams. However, recent studies have shown that high-Ti magnetite can be present high-temperature hydrothermal deposits, suggesting a probable origin. This also calls for reconsideration necessary modification of currently available issue is particularly acute iron...
is a major global pathogen, and its infection represents key factor in the etiology of various gastric diseases, including gastritis, peptic ulcers, carcinoma. The efficacy current standard treatment for
The increasing prevalence of multidrug-resistant Helicobacter pylori strains has created an urgent need for alternative therapeutic regimens that complement the current antibiotic treatment strategies H. eradication; however, this is greatly hampered due to a lack “druggable” targets. Although CFAs are present in cytoplasmic membranes at high levels, their physiological role not been established. In report, deletion CFA synthase CfaS was shown attenuate acid and drug resistance, immune...
Summary Antibiotic resistance in Helicobacter pylori has been growing worldwide with current treatment regimens. Development of new compounds for H. infections is urgently required to achieve a successful eradication therapy the future. Armeniaspirols, novel class natural products isolated from Streptomyces armeniacus , have previously identified as antibacterial agents against Gram‐positive pathogens. In this study, we found that armeniaspirol A (ARM1) exhibited potent activity including...
Two novel diterpenoids and ten known analogs were obtained from the tuber of <italic>Icacina trichantha</italic>. All compounds exhibited antibacterial activity against <italic>Helicobacter pylori</italic> strains with MIC values ranging 8 to 64 μg mL<sup>−1</sup>.
Abstract Helicobacter pylori ( H. ) is a group‐1 definite pathogenic carcinogen that infects approximately half of the global population, yet no species‐specific chemotherapy has been developed. It previously discovered encodes an atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway to produce unsaturated acids (UFA) as well superoxide (ROS). Here, it demonstrated essential for growth and gastric colonization by retaining UFA synthesis producing ROS, respectively,...
Abstract Genetic polymorphisms in DNA repair genes may influence individual variation capacity, which be associated with risk of gastric antrum adenocarcinoma (GAA) related to Helicobacter pylori infection. This study, including 361 GAAs and 616 controls without any evidence tumors, was designed evaluate the association between XPC Ala499Val (RS#2228000) Lys939Gln (RS#2228001), XPD Lys751Gln (RS#13181), XRCC4 Ala247Ser (RS#3734091) Ser298Asn (RS#1805377), GAA for Guangxi population by means...
Helicobacter pylori is a major global pathogen and has been implicated in gastritis, peptic ulcer, gastric carcinoma. The efficacy of the extensive therapy H. infection with antibiotics compromised by development drug resistance toxicity toward human gut microbiota, which urgently demands novel selective antibacterial strategies. present study was mainly performed to assess vitro vivo effects natural herbal compound, dihydrotanshinone I (DHT), against standard clinical strains. DHT...
In order to degrade in-car formaldehyde gas, graphene oxide (GO), cerium (Ce), and TiO2 were organically combined by one-step sol–gel method. Then the mixed collosol was coated onto surface of inorganic glass substrates form Ce-GO-TiO2 composite film way immersion, coating, calcinations. The morphology crystal structure as-prepared studied a series detection techniques. photocatalytic performance this analyzed degradation effect under simulated sunlight. results showed that had inbuilt...