A5058549163- Cellular Mechanics and Interactions
- Cell Adhesion Molecules Research
- Polymer Surface Interaction Studies
- Advanced Electron Microscopy Techniques and Applications
- Trace Elements in Health
- Extracellular vesicles in disease
- Microtubule and mitosis dynamics
- Supramolecular Self-Assembly in Materials
Université Paris Cité
2023
Institut Pasteur
2023
Centre National de la Recherche Scientifique
2023
Université Paris-Saclay
2023
Tunnelling nanotubes (TNTs) connect distant cells and mediate cargo transfer for intercellular communication in physiological pathological contexts. How generate these actin-mediated protrusions to span lengths beyond those attainable by canonical filopodia remains unknown. Through a combination of micropatterning, microscopy, optical tweezer-based approaches, we demonstrate that TNTs formed through the outward extension actin achieve distances greater than mean length branched...
ABSTRACT Actin-based protrusions are at the base of many fundamental cellular processes, such as cell adhesion, migration and intercellular communication. In recent decades, discovery new types actin-based with unique functions has enriched our comprehension processes. However, repertoire continues to expand, rationale behind classification newly identified previously known structures becomes unclear. Although current nomenclature allows good categorization based on their functions, it...