- Palliative Care and End-of-Life Issues
- Reproductive Biology and Fertility
- Family and Patient Care in Intensive Care Units
- S100 Proteins and Annexins
- Sperm and Testicular Function
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Hip and Femur Fractures
- Frailty in Older Adults
- Smart Materials for Construction
- Substance Abuse Treatment and Outcomes
- Multilevel Inverters and Converters
- Muscle and Compartmental Disorders
- Gout, Hyperuricemia, Uric Acid
- Childhood Cancer Survivors' Quality of Life
- Vitamin C and Antioxidants Research
- Alcohol Consumption and Health Effects
- Maternal and Perinatal Health Interventions
- Stroke Rehabilitation and Recovery
- Retinal Imaging and Analysis
- Inflammasome and immune disorders
- Osteoarthritis Treatment and Mechanisms
- Maternal Mental Health During Pregnancy and Postpartum
- Recycling and Waste Management Techniques
- Healthcare and Environmental Waste Management
Fuzhou University
2024
Icahn School of Medicine at Mount Sinai
2023-2024
General Hospital of Shenyang Military Region
2024
North China Electric Power University
2024
Vanderbilt University Medical Center
2023
Nanjing Medical University
2022-2023
Second Affiliated Hospital of Nanjing Medical University
2023
First Affiliated Hospital of GuangXi Medical University
2023
Guangxi Medical University
2023
Chang Gung University
2023
To date, the benefit of intravenous thrombolysis for acute ischemic stroke (AIS) patients without advanced neuroimaging selection is confined to within 4.5 h onset. Our phase II EXIT-BT (Extending tIme window Thrombolysis by ButylphThalide up 6 after onset) trial suggested safety, feasibility, and potential tenecteplase (TNK) in AIS between The EXIT-BT2 a pivotal study undertaken confirm or refute this signal.
Purpose: To determine the differences of metabolites and metabolic pathways between patients with proliferative diabetic retinopathy (PDR) without diabetes (nondiabetic controls) in plasma vitreous, respectively, to characterize relationship vitreous profiles. Methods: Liquid chromatography/tandem mass spectrometry technology was performed distinct metabolite profiles vitreous. A total 139 samples from 88 PDR 51 nondiabetic controls, as well 74 23 were screened. Pathway analysis using...
Purpose: Adiponectin has been shown to exert potent anti-inflammatory activities in a range of systemic inflammatory diseases. This study aimed investigate the potential therapeutic effects KS23, globular adiponectin-derived peptide, on endotoxin-induced uveitis (EIU) rats and lipopolysaccharide (LPS)-stimulated mouse macrophage-like RAW 264.7 cells. Methods: EIU was induced Lewis by subcutaneous injection LPS into single footpad. KS23 or phosphate-buffered saline (PBS) administered...
Nutritionally unhealthy obesity is a newly introduced phenotype characterized by combined condition of malnutrition and obesity. This study aims to explore the influence nutritional status on prevalence outcome hypertension.Participants collected from National Health Nutrition Examination Survey (NHANES) database were divided into four subgroups according their conditions, as defined waist circumference serum albumin concentration. The lean-well-nourished was set reference group. Logistic...
Hepatic dysfunction is one of the clinical features in severe malaria. However, mechanism hepatic injury during malaria still unknown. Myeloid-related protein (MRP) 14 abundantly expressed by myeloid cells and involved various inflammatory diseases. We previously reported that serum MRP14 elevated mice infected with Plasmodium berghei ANKA. In order to verify whether extracellular pathology rodent malaria, we intravenously administrated recombinant (rMRP14) P. The administration rMRP14 did...
Abstract Introduction Increasing numbers of individuals admitted to hospitals for trauma are older adults, many whom also have underlying serious illnesses. Older adults with illness benefit from palliative care, but the care needs seriously ill not been elucidated. We hypothesize that a high prevalence pain, depression, and unpaid caregiving hours before admission. Methods Using Health Retirement Study data (2008–2018) linked Medicare claims, we identified patients 66 years or who met an...
Abstract We aim to investigate the influence of waist circumference and body mass index (BMI) on all‐cause death cardiovascular‐specific in patients with hypertension. This prospective cohort study, based measurements hypertension, provided risk estimates mortality cardiovascular events. The circumference‐to‐BMI ratio (WtBR) is an anthropometric measure integrating BMI. utilized multivariable Cox regression analysis, restricted cubic spline model, Kaplan‐Meier plot, random forest sensitivity...
Abstract Pentachloronitrobenzene (PCNB) is an organochlorine fungicide widely used for crop production and has become environmental concern. Little known about the effect of PCNB on ovarian steroidogenesis follicular development. We found that stimulated Star expression progesterone in cultured rat granulosa cells a dose-dependent manner. activated mitogen-activated protein kinase (MAPK3/1) extracellulat regulated (ERK1/2), thus inhibition either A (PKA) or MAPK3/1 signaling pathway...
Cryopreservation induces sperm cryoinjuries, including physiological and functional changes. However, the molecular mechanisms of cryoinjury cryoresistance are still unknown. Cryoresistance or freeze tolerance varies across species, boar is more susceptible to cold stress. Contrary sperm, giant panda appears be strongly freeze-tolerant capable surviving repeated cycles freeze-thawing. In this study, differentially expressed (DE) PIWI-interacting RNAs (piRNAs) fresh frozen-thawed with...
Cryopreservation induces capacitation-like (cryo-capacitation) changes, similar to natural capacitation, and affects the fertility potential of post-thawed sperm. The molecular mechanism sperm cryo-capacitation during cryopreservation remains unknown. PIWI-interacting RNAs (piRNAs) have been reported be involved in regulation motility, chemotaxis. In this study, protein tyrosine phosphatase nonreceptor type 7 (PTPN7) was positively targeted by piR-121380 after a dual luciferase assay. mRNA...
Abstract Introduction Serious illness is a life‐limiting condition negatively impacting daily function, quality of life, or excessively straining caregivers. Over 1 million older seriously ill adults undergo major surgery annually, and national guidelines recommend that palliative care be available to all patients. However, the needs elective surgical patients are incompletely described. Understanding baseline caregiving symptom burden among could inform interventions improve outcomes....
Anwar, Amber; Abu Kar, Sarah; Binari, Laura; Wang, Yihan; Shawar, Saed Author Information
Given the complex care needs of older adults receiving home health (HHC), it is important for HHC clinicians to identify those with limited prognosis who may benefit from a transition hospice care.
Background Tuberculosis (TB) is a chronic infectious disease. Bone and joint TB common type of extrapulmonary often occurs secondary to infection. In this study, we aimed find the difference in blood examination results patients with bone by using machine learning (ML) establish diagnostic model help clinicians better diagnose disease allow receive timely treatment. Methods A total 1,667 were finally enrolled study. Patients randomly assigned training validation cohorts. The cohort included...
Approximately 70% of postpartum women in Taiwan choose care institutions for their confinement. However, few studies have explored the follow-up relationship between confinement location and, respectively, maternal psychological and role adaptation.To explore differences psychology adaptation two different locations to analyze predictors confidence competence at six-months postpartum.A comparative research design was adopted. We recruited a convenience sample groups confined, nursing centers...
Objective To systematically evaluate the efficacy of triamcinolone acetonide combined with sodium hyaluronan in treatment knee osteoarthritis. Methods According to Meta-analysis requirements, The Literature researchwas published both at demestic and abroad from database founded March 2019. retrieval was performed CBM, CNKI, PubMed, Springer, Embase databases, Wanfang, Weipu, Cochrane Library, etc. total effective rate Lysholm joint score systematicallyevaluated by using software named...