A5015660049- Innovative Microfluidic and Catalytic Techniques Innovation
- Electrowetting and Microfluidic Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Sensor and Energy Harvesting Materials
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Advanced Chemical Sensor Technologies
- Neuroscience and Neural Engineering
- Electrohydrodynamics and Fluid Dynamics
- Biosensors and Analytical Detection
- Analytical Chemistry and Sensors
- Cerebrospinal fluid and hydrocephalus
- 3D Printing in Biomedical Research
- Cardiac Arrest and Resuscitation
- Thermal Regulation in Medicine
- Traumatic Brain Injury and Neurovascular Disturbances
- Biomedical and Chemical Research
- Modular Robots and Swarm Intelligence
- Electrochemical sensors and biosensors
- Transplantation: Methods and Outcomes
- Pickering emulsions and particle stabilization
- Aortic Disease and Treatment Approaches
Northwestern University
2024-2025
Johns Hopkins University
2019-2020
Johns Hopkins Medicine
2020
Samsung (South Korea)
2016
Imperial College London
2011-2015
Blood lactate concentration is an established circulating biomarker for measuring muscle acidity and can be evaluated monitoring endurance, training routines, or athletic performance. Sweat alternative biofluid that may serve similar purposes offers the advantage of noninvasive collection continuous monitoring. The relationship between blood dynamic sweat biochemistry wearable engineering applications in physiological fitness remains poorly defined. Here, we developed a microfluidic band...
Combinatorial chemical evolution is used to select oil-water droplet interfaces that drive inorganic nanoparticle synthesis.
We present a fully integrated droplet-based microfluidic platform for the high-throughput assessment of photodynamic therapy photosensitizer (PDT) efficacy on Escherichia coli. The described is able to controllably encapsulate cells and within pL-volume droplets, incubate droplets over course several days, add predetermined concentrations viability assay agents, expose varying doses electromagnetic radiation, detect both live dead online score cell viability. after encapsulation incubation...
Herein, we describe the development of a multilayer droplet microfluidic system for creating concentration gradients and generating microdroplets varying composition high-throughput biochemical cell-based screening applications. The 3D droplet-based device consists multiple PDMS layers, which are used to generate logarithmic gradient reagent profiles. Parallel flow focusing structures form picoliter-sized droplets defined volumes but composition. As proof concept, demonstrate rapid enzymatic...
Ketones, such as beta-hydroxybutyrate (BHB), are important metabolites that can be used to monitor for conditions diabetic ketoacidosis (DKA) and ketosis. Compared conventional approaches rely on samples of urine or blood evaluated using laboratory techniques, processes monitoring ketones in sweat on-body sensors offer significant advantages. Here, we report a class soft, skin-interfaced microfluidic devices quantify the concentrations BHB based simple low-cost colorimetric schemes. These...
Amino acids are essential for protein synthesis and metabolic processes in support of homeostatic balance healthy body functions. This study quantitatively investigates eccrine sweat as a significant channel for...
We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in monolithic format. Sequential operations separation, compartmentalisation and concentration counter were conducted on chip. This describes use microfluidics for preservation chromatographic separations, its potential application as frequency fraction collector.
Herein, we describe the monolithic integration of a multiphase microfluidic system to microcapillary gel electrophoresis (μCGE) architecture for complete isolation and storage separated analyte bands. Within this platform, molecules are using microchannel electrophoresis, eluted bands stored in sequence approximately 40-600 encapsulating microdroplets. Importantly, employing such allows total control droplet size, shape, composition. This approach is utilized separate, optically detect,...
The development of microfluidic platforms for performing chemistry and biology has in large part been driven by a range potential benefits that accompany system miniaturisation. Advantages include the ability to efficiently process nano- femoto- liter volumes sample, facile integration functional components, an intrinsic predisposition towards large-scale multiplexing, enhanced analytical throughput, improved control reduced instrumental footprints.1 In recent years much interest focussed on...
The development of microfluidic platforms for performing chemistry and biology has in large part been driven by a range potential benefits that accompany system miniaturisation. Advantages include the ability to efficiently process nano- femoto- liter volumes sample, facile integration functional components, an intrinsic predisposition towards large-scale multiplexing, enhanced analytical throughput, improved control reduced instrumental footprints.1 In recent years much interest focussed on...