A5026063467- Sepsis Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Dermatology and Skin Diseases
- Venous Thromboembolism Diagnosis and Management
- Neonatal skin health care
- Streptococcal Infections and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Nail Diseases and Treatments
- Fungal Infections and Studies
- Myasthenia Gravis and Thymoma
- Histiocytic Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Urinary Tract Infections Management
- Pelvic floor disorders treatments
- CAR-T cell therapy research
- Dermatological diseases and infestations
- Medicine and Dermatology Studies History
- Pharmacovigilance and Adverse Drug Reactions
- Cancer Immunotherapy and Biomarkers
- Neutropenia and Cancer Infections
- Platelet Disorders and Treatments
- Frailty in Older Adults
- Nutrition and Health in Aging
- Eosinophilic Disorders and Syndromes
- Leprosy Research and Treatment
University of Lucerne
2016-2024
University Children's Hospital Zurich
2024
Luzerner Kantonsspital
2024
University Hospital of Basel
2019
Kantonsspital Aarau
2014-2015
University of Basel
2015
Only a small proportion of blood cultures routinely performed in emergency department (ED) patients is positive. Multiple clinical scores and biomarkers have previously been examined for their ability to predict bacteremia. Conclusive validation these essential. This observational cohort study included with suspected infection who had culture sampling at ED admission. We assessed 5 admission concentrations procalcitonin (PCT), C-reactive protein (CRP), lymphocyte white cell counts, the...
Urinary tract infections (UTIs) are common drivers of antibiotic use. The minimal effective duration therapy for UTIs is unknown, but any reduction important to diminish selection pressure resistance, costs, and drug-related side-effects. aim this study was investigate whether an algorithm based on procalcitonin (PCT) quantitative pyuria reduces exposure. From April 2012 March 2014, we conducted a factorial design randomized controlled open-label trial. Immunocompetent adults with...
Abstract Early differentiation of erysipelas from deep vein thrombosis ( DVT ) based solely on clinical signs and symptoms is challenging. There a lack data regarding the usefulness inflammatory biomarkers procalcitonin PCT ), C‐reactive protein CRP white blood cell WBC count in diagnosis localized cutaneous infections. Herein, we investigated diagnostic value markers prospective at‐risk patient population. This an observational quality control study including consecutive patients presenting...
Abstract Background Tinea capitis (TC) is the most frequent dermatophyte infection in children requiring systemic and topical treatment for several weeks. Traditionally, diagnosis monitoring were based on microscopic examination fungal culture of scales plucked hairs, which both have significant limitations. Objectives To investigate role polymerase chain reaction (PCR) TC. Methods Scales hairs with TC investigated by PCR, at baseline during antifungal treatment. Results Seventeen included....
The Glasgow Prognostic Score (GPS) is useful for predicting long-term mortality in cancer patients. Our aim was to validate the GPS ED patients with different cancer-related urgency and investigate whether biomarkers would improve its accuracy. We followed consecutive medical presenting a tertiary care hospital Switzerland. Upon admission, we measured procalcitonin (PCT), white blood cell count, urea, 25-hydroxyvitamin D, corrected calcium, C-reactive protein, albumin calculated GPS. Of 341...
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Im Namen der Swiss Grand Round for Vascular Anomalies in Children (SGVAC). Infantile Hämangiome (IH) sind mit einer Prävalenz von 4-5% die häufigsten benignen Tumore des Kindesalters(1). Seit Entdeckung Wirksamkeit Propranolol zur Behandlung problematischer IH im Jahr 2008 und nachfolgender Zulassung Schweiz 2014 hat sich deren Management grundlegend geändert(2,3). 2009 wurden erstmals „Schweizer Richtlinien Propranolol-Therapie infantiler Hämangiome“ Childhood (SGVAC) veröffentlicht 2016...
Au nom du Swiss Grand Round for Vascular Anomalies in Children (SGVAC). Avec une prévalence de 4-5% les hémangiomes infantiles (HI) sont tumeurs bénignes plus fréquentes pendant l’enfance(1). Depuis la découverte en 2008 l’efficacité propranolol dans le traitement des HI problématiques et l’admission Suisse 2014, prise charge a fondamentalement changé(2,3). En 2009 ont été éditées premières «Recommandations suisses pour par propranolol», revues 2016, au Childhood (SGVAC)(4,5). Les...
There are no well-validated risk scores for patients with oncological and hematological malignancies presenting to the emergency department (ED). Previous research found prognostic blood biomarker pro-adrenomedullin (proADM) be associated infection-related complications mortality thus may helpful in managing febrile malignancies. Yet value of proADM general ED remains unclear. Herein, objective this study is evaluate potential clinical parameters a consecutive cohort regard ICU admission...