A5110948164- Renal cell carcinoma treatment
- Renal and related cancers
- Lubricants and Their Additives
- Electrocatalysts for Energy Conversion
- Bladder and Urothelial Cancer Treatments
- Advanced battery technologies research
- Tribology and Wear Analysis
- Fuel Cells and Related Materials
- Ferroptosis and cancer prognosis
- Digital Marketing and Social Media
- Adhesion, Friction, and Surface Interactions
- Aquatic Ecosystems and Phytoplankton Dynamics
- Drug-Induced Hepatotoxicity and Protection
- Plant Stress Responses and Tolerance
- Epigenetics and DNA Methylation
- Algal biology and biofuel production
- Pancreatic and Hepatic Oncology Research
- Constructed Wetlands for Wastewater Treatment
- Biocrusts and Microbial Ecology
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Force Microscopy Techniques and Applications
- Cell death mechanisms and regulation
- Nanoplatforms for cancer theranostics
- Inflammasome and immune disorders
Lanzhou University
2022-2025
Lanzhou Institute of Chemical Physics
2022-2025
Chinese Academy of Sciences
2022-2025
China Medical University
2025
Fourth Affiliated Hospital of China Medical University
2025
Central South University
2020-2025
Zhejiang A & F University
2022-2025
Beijing Institute of Technology
2022-2025
Second Xiangya Hospital of Central South University
2023-2025
Second Affiliated Hospital of Nanjing Medical University
2022-2025
Abstract Currently, certain cancer patients exhibit resistance to radiotherapy due reduced DNA damage under hypoxic conditions and acquired immune tolerance triggered by transforming growth factor‐β1 (TGF‐β1) membrane‐localized programmed death ligand‐1 (PD‐L1). Meanwhile, cytoplasm‐distributed PD‐L1 induces through accelerating repair (DDR). However, the disability of clinically used antibodies in inhibiting limits their effectiveness. Therefore, a nanoadjuvant is developed sensitize via...
Abstract Proton exchange membrane fuel cells (PEMFCs) have attracted significant interest as a promising alternative technology to the combustion engine power next‐generation vehicles with zero emission. Among various technological targets, system cost and durability are currently identified main obstacles toward large‐scale implementation of PEMFCs. Platinum‐group‐metal‐based (PGM‐based) catalysts most efficient catalyst for rate‐limiting cathodic oxygen reduction reaction in PEMFCs take...
Background: Chitinase-3-like protein 1 (CHI3L1) is overexpressed in various types of tumors, especially glioma, and contributes to tumor progression. However, the definite role CHI3L1 involved pathway glioma progression are not completely understood. Methods: expression human gliomas its association with patient survival was determined using enzyme-linked immunosorbent assay, western blot, immunohistochemistry, public databases. Single-cell RNA-seq used characterize landscape myeloid cells....
Abstract The cytoplasmic pattern recognition receptor, absent in melanoma 2 (AIM2), detects cytosolic DNA, activating the inflammasome and resulting pro-inflammatory cytokine production pyroptotic cell death. Recent research has illuminated AIM2’s contributions to PANoptosis host defense. However, role of AIM2 acetaminophen (APAP)-induced hepatoxicity remains enigmatic. In this study, we unveil novel function as a negative regulator pathogenesis APAP-induced liver damage aged mice,...
Images, with their direct content experience, have become essential in tourists’ narratives of accommodation sharing. Although visual plays an important role influencing user decisions, research on hotel images often neglects the significance sensory elements. Sensory elements help shape perceptions and evaluations experiences. This study explores how marketing review affect sales from a perspective. The employs combination hybrid machine vision econometric methods to examine visual,...
With the emphasis of modern societal development on ecological environment, urban environmental issues have been lessened. However, green space occupies a significant amount land resources, leading to more prominent human-land conflicts in some areas, thus creating serious social that urgently require solutions. As result, and factors must be integrated into sustainability planning. Using Chinese city Fuzhou as an example, this study constructed adaptive cycle model framework for sustainable...
Abstract The development of efficient, high‐performance catalysts for hydrogen evolution reaction (HER) remains a significant challenge, especially in seawater media. Here, RuIr alloy are prepared by the polyol reduction method. Compared with single‐metal catalysts, exhibited higher activity and stability electrolysis due to their greater number reactive sites solubility resistance. has an overpotential 75 mV@10 mA cm −2 , which is similar that Pt/C (73 mV), can operate stably 100 hours...
Visualizing the motion of water droplets and understanding their electrification behavior holds significance for applications related to droplet transport, self-cleaning, anti-icing/deicing providing a comprehensive explanation solid–liquid triboelectrification mechanism. Here, by constructing microcolumnar structures on polytetrafluoroethylene surface, droplet-based single electrode triboelectric nanogenerator was fabricated visualizing charge dynamics when bounces hydrophobic surface. The...
In this study, we performed bioinformatics analysis to identify the competing endogenous RNAs (ceRNAs) that regulate bladder cancer (BCa) progression. RNA-sequencing data identified 2451 differentially expressed mRNAs, 174 lncRNAs, and 186 microRNAs (miRNAs) in BCa tissues (n=414) compared normal urothelial (n=19) from TGCA database. CeRNA network of lncRNAs mRNAs showed strong positive correlation between lncRNA MAGI2-AS3 Tensin 1 (TNS1) mRNA tissues. Bioinformatics also both TNS1 sequences...
Ferroptosis induced by lipid peroxidation is closely related to cancer biology. Prostate (PCa) not only a malignant tumor but also metabolic disease. Previous studies have identified ferroptosis as an important pathophysiological pathway in PCa development and treatment, its role the prognosis of less well known. In this study, we constructed nine-ferroptosis-related gene risk model that demonstrated strong prognostic therapeutic predictive power. The higher score calculated was...
Background: Collagen represents a prominent constituent of the tumor’s extracellular matrix (ECM). Nonetheless, its correlation with molecular subtype attributes clear cell renal carcinoma (ccRCC) remains elusive. Our objective is to delineate collagen-associated subtypes and further construct diagnostic model, offering insights conducive precise selection ccRCC patients for immunotherapeutic interventions. Methods: We performed unsupervised non-negative factorization (NMF) analysis on...
Purpose The purpose of this paper is to study the importance image data in hotel selection-recommendation using different types cognitive features and explore whether there are reinforcing effects among these features. Design/methodology/approach This represents user-generated images “cognitive” a knowledge graph through multidimensional (shallow, middle deep) analysis. approach highlights clustering destination imagery. Findings develops novel model based on sentiment attribute...
Inflammation is critical for obesity and obesity-induced insulin resistance (IR). In this study, we reveal the function mechanism of acarbose on adipose tissue macrophage (ATM)-mediated inflammation in IR. First, enhances abundance propionic acid-producing Parasutterella, therefore indirectly inhibiting survival proinflammatory M1-like ATMs via GPR43. Most interestingly, can directly inhibit ATM-mediated through GPR120. Diet-induced obese mice exhibit nitrobenzoxadiazoles (NBD)...
Through the synergy of friction and copper nanoparticles, targeted introduction click chemistry is achieved during steel–steel process, which then acts on process to achieve satisfactory tribological gains.
Background: As a transcription factor, Zic family member 2 (ZIC2) has been involved in more and studies of tumorigenesis, which proved by our research team to be an effective prognostic marker for Pan-cancer.However, the prognosis, tumor promoting effect regulatory mechanism ZIC2 clear cell renal carcinoma (ccRCC) are still unknown.Methods: The potential clinical significance was evaluated bioinformatics analysis using data from TCGA, GEO, ArrayExpress sets.WB IHC were used detect expression...
Abstract Substantial progress has been made in stimulus‐responsive and performance‐tunable hydrogels, yet endowing organogels with dynamic adaptive properties remains challenging. Especially, the development of functional oleogel materials is further constrained by weak interactions between oil gel network, along high viscosity oil. Herein, state self‐adaptability oleogels enabled constructing mechanical responsive covalent networks via ring‐opening polymerization thioctic acid (TA)....