A5108049214- CAR-T cell therapy research
- Biosimilars and Bioanalytical Methods
- Lymphoma Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Asthma and respiratory diseases
- Advanced Computing and Algorithms
- Image and Video Quality Assessment
- Gastric Cancer Management and Outcomes
- Advanced MIMO Systems Optimization
- Cancer-related gene regulation
- Radio Frequency Integrated Circuit Design
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Impact of Light on Environment and Health
- Olfactory and Sensory Function Studies
- COVID-19 Clinical Research Studies
- Ovarian function and disorders
- Sarcoma Diagnosis and Treatment
- Reproductive Biology and Fertility
- Cancer Immunotherapy and Biomarkers
- Reproductive Health and Technologies
- Colorectal and Anal Carcinomas
- Soil and Land Suitability Analysis
- Long-Term Effects of COVID-19
- RNA modifications and cancer
Chengdu Second People's Hospital
2022-2025
Zhujiang Hospital
2023-2025
Southern Medical University
2023-2025
Glenmark Pharmaceuticals (India)
2022-2024
Yichang Central People's Hospital
2023-2024
China Three Gorges University
2023-2024
Shanghai Jiao Tong University
2022-2024
Ruijin Hospital
2001-2024
Shanghai Institute of Hematology
2001-2024
Jining Medical University
2024
Additional outpatient therapies which are readily accessible will be essential to reduce COVID-19 illness progression in high risk individuals. Especially as the virus continues mutate with greater transmissibility despite increased global vaccination.A randomized, double-blind, multicentre, parallel group, placebo-controlled phase III clinical trial evaluated ability of nitric oxide (NO) rapidly eradicate nasal SARS-CoV-2 RNA. Adults (18-70 years) mild symptomatic were confirmed by...
The repair and reconstruction of bone defects are still major problems to be solved in the field orthopedics. Meanwhile, 3D-bioprinted active implants may provide a new effective solution. In this case, we used bioink prepared from patient's autologous platelet-rich plasma (PRP) combined with polycaprolactone/β-tricalcium phosphate (PCL/β-TCP) composite scaffold material print personalized PCL/β-TCP/PRP scaffolds layer by through 3D bioprinting technology. was then applied patient...
Fine-tuning is the process of adapting pre-trained large language models (LLMs) for downstream tasks. Due to substantial parameters, fine-tuning LLMs on mobile devices demands considerable memory resources, and suffers from high communication overhead long delay. In this paper, we propose an efficient LLM scheme in wireless networks, named Split Fine-Tuning (SFT), which can accommodate devices. Specifically, split into a server-side part edge server device-side device satisfy constraint. All...
Fine-tuning a large language model (LLM) using the local data of edge users can enable personalized services and applications. For privacy protection, prevalent solution adopts distributed learning for fine-tuning integrates low-rank adaptation (LoRA) to reduce users' computational load. However, as number increases, numerous simultaneously communicate with server, multiple server-side models concurrently execute on leading significant communication congestion memory pressure. In this paper,...
Rectal schwannoma (RS) is a rare subtype of that presents diagnostic challenges owing to its clinical rarity. The absence typical symptoms, specific signs, and distinctive radiographic findings often hinders clinicians from reaching definitive diagnosis before surgical intervention. Herein, we report case RS who underwent complete resection through endoscopic full-thickness (EFTR) discuss the clinical, imaging, pathological features for differential diagnosis. A 71-year-old Chinese woman...
Gastric cancer (GC) ranks third for deaths worldwide, and glycolysis is a hallmark of several cancers, including GC. TEAD4 plays role in establishing an oncogenic cascade Whether can influence the GC cells remains uncovered. Hence, this study attempted to investigate impact on by TEAD4.By using bioinformatics analysis, differentially expressed mRNAs were screened, downstream regulatory genes predicted. Expression levels PKMYT1 assessed qRT-PCR. The binding sites between predicted JASPAR...
Abstract Background To compare the efficacy and safety of follitropin delta in its individualized fixed-dose regimen with alfa a conventional adjustable dosing Chinese women. Methods This was subgroup analysis randomized, multi-center, assessor-blind, non-inferiority trial (GRAPE) including 759 women (aged 20–40 years) recruited 16 reproductive medicine clinics China. Women were randomized 1:1 ratio to be treated either dose based on anti-Müllerian hormone (AMH) body weight or following...
Purpose: Combination intranasal corticosteroid and antihistamine sprays are a first-line treatment option for allergic rhinitis (AR), of which Azelastine Hydrochloride Fluticasone Propionate nasal spray (AZE/FLU; Dymista ® ), Olopatadine Mometasone Furoate Monohydrate (OLO/MOM; Ryaltris ) currently registered in Australia. As it is not known how patients value attributes current combination sprays, this observational, real-world clinical study aimed to understand patients’ satisfaction with,...
GSP301 nasal spray is a fixed-dose combination of the antihistamine olopatadine hydrochloride and corticosteroid mometasone furoate.To evaluate efficacy, safety, tolerability in pediatric patients (aged ≥6 to <12 years) with seasonal allergic rhinitis (SAR).This double-blind, randomized, parallel-group study randomized 446 eligible 1:1 (GSP301 [olopatadine 665 μg furoate 25 μg] or placebo) as 1 spray/each nostril twice daily for 14 days. The primary end point was change from baseline...
Pulmonary dysfunction after stroke is increasingly gaining attention from clinical and rehabilitation specialists. However, owing to cognitive motor in patients with stroke, determining the pulmonary function of these remains challenging. The present study aimed devise a simple method for an early evaluation stroke.Overall, 41 recovery period (stroke group) 22 matched healthy controls (control were included study. We first collected data regarding baseline characteristics all participants....
The incidence and mortality of colorectal cancer (CRC) are among the highest in world, its occurrence development closely related to tumor neovascularization. When balance between pigment epithelium-derived factors (PEDF) that inhibit angiogenesis vascular endothelial growth (VEGF) stimulate is broken, out control, resulting development. Therefore, it very necessary find more therapeutic targets for CRC early intervention later treatment.
Lipid metabolism reprogramming is suspected to exist in pre-cancerous lesions, including colorectal adenoma. Screening colonoscopy frequently reveals chicken skin mucosa (CSM; white or yellow-white speckled mucosa) surrounding polyps, caused by macrophages engulfing and accumulating the lipids decomposed colon cells adjacent tumors. CSM-positive polyps are associated with various diseases; however, their prognosis varies greatly. Cold snare polypectomy commonly used resect lesions up 10 15...
Wasp sting injuries pose a significant threat to public health, especially in areas with abundant trees. Mortality rates are alarmingly high, reports indicating that up 70% or more of cases result multiple organ dysfunction syndrome (MODS). It is crucial for emergency and critical care physicians promptly identify implement effective measures reduce the occurrence MODS patients who have been stung by wasps. Therefore, finding reliable predictive indicator utmost importance. We conducted...
The G protein-coupled oestrogen receptor (GPER) 1 mediates non-genomic oestrogen-related signalling and plays an important role in the regulation of cell growth programmed death through multiple downstream pathways. Despite increasing interest GPER1 cancer development, no pan-cancer analysis has been available for GPER1.In this study we performed a comprehensive via Human Protein Atlas (HPA), Cancer Genome (TCGA), University California, Santa Cruz Xena (UCSC XENA), Genotype-Tissue Expression...