A5043345285- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Antibiotics Pharmacokinetics and Efficacy
- Sepsis Diagnosis and Treatment
- Urinary Tract Infections Management
- Urinary Bladder and Prostate Research
- Pharmacological Effects of Natural Compounds
- Neurogenesis and neuroplasticity mechanisms
- RNA modifications and cancer
- Central Venous Catheters and Hemodialysis
- Bacterial Identification and Susceptibility Testing
- Pediatric Urology and Nephrology Studies
- Ubiquitin and proteasome pathways
- Medicinal Plant Pharmacodynamics Research
- Intensive Care Unit Cognitive Disorders
- Antibiotic Use and Resistance
- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Traditional Chinese Medicine Analysis
- Animal Genetics and Reproduction
- Neuroinflammation and Neurodegeneration Mechanisms
- Ferroptosis and cancer prognosis
- Parkinson's Disease Mechanisms and Treatments
Northern Jiangsu People's Hospital
2024-2025
Baotou Medical College
2025
Zhejiang University
2025
Hangzhou Medical College
2025
Zhejiang Provincial People's Hospital
2025
Yangzhou University
2022-2024
Henan Academy of Agricultural Sciences
2024
Parkinson's disease (PD) is a common neurodegenerative and difficult to treat due its elusive mechanisms. Recent studies have identified striking association between oligodendrocytes PD progression, yet how regulate the pathogenesis of still unknown. Here, we show that G-protein-coupled receptor 37 (GPR37) upregulated in substantia nigra prosaposin (PSAP) secretion increased parkinsonian mice. The released PSAP can induce interleukin (IL)-6 upregulation from via GPR37-dependent pathway,...
ABSTRACT Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with multidrug-resistant organisms (MDROs), which result high mortality rates and substantial healthcare burdens. Recognition intervention are paramount. This study aimed build a prediction model for MDRO among NICU patients HAP. Clinical laboratory data were collected from of grade-A tertiary hospital. Five machine learning models (logistic...
Patients in neuro-ICU are at a high risk of developing nosocomial CRKP infection owing to complex conditions, critical illness, and frequent invasive procedures. However, studies focused on constructing prediction models for assessing the neurocritically ill patients lacking present. Therefore, this study aims establish simple-to-use nomogram predicting admitted neuro-ICU. Three easily accessed variables were included model, including number antibiotics used, surgery, length stay. This might...
Abstract Background There was significant difference in muscle development between fat-type and lean-type pig breeds. Methods results In current study, transcriptome analysis bioinformatics were used to compare the longissimus dorsi (LD) at three time-points (38 days post coitus (dpc), 58 dpc, 78 dpc ) Huainan (HN) Large white (LW) A total of 24500 transcripts obtained 18 samples, 2319, 2799, 3713 differently expressed genes (DEGs) identified these two breeds 38 respectively. And number...
Abstract Objective This study aimed to develop and apply a nomogram with good accuracy predict the risk of CRAB infections in neuro-critically ill patients. In addition, difficulties expectations application such tool clinical practice was investigated. Methods A mixed methods sequential explanatory design utilized. We first conducted retrospective identify factors for development patients; further validate predictive model. Then, based on developed tool, medical staff neuro-ICU were...