A5008399240- Cell Adhesion Molecules Research
- Immune cells in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Nanoplatforms for cancer theranostics
- Cardiac and Coronary Surgery Techniques
- Extracellular vesicles in disease
- Cancer Immunotherapy and Biomarkers
- Acute Myocardial Infarction Research
- Antibiotics Pharmacokinetics and Efficacy
- Angiogenesis and VEGF in Cancer
- Peptidase Inhibition and Analysis
- Genetic Syndromes and Imprinting
- Ferroptosis and cancer prognosis
- CAR-T cell therapy research
- Parathyroid Disorders and Treatments
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Surgical Treatments
- Nanoparticle-Based Drug Delivery
- Sepsis Diagnosis and Treatment
- Receptor Mechanisms and Signaling
- Clinical practice guidelines implementation
- Frailty in Older Adults
- Analytical Chemistry and Sensors
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Fujian Medical University
2024
China National Petroleum Corporation (China)
2021-2024
Fujian Provincial Cancer Hospital
2015-2024
Third Xiangya Hospital
2021-2023
Central South University
2001-2023
Xiangya Hospital Central South University
2019-2023
Dana-Farber Cancer Institute
2023
Harvard University
2023
Second Xiangya Hospital of Central South University
2001-2021
Blood specimens collected for culture by using the high-volume resin-based BACTEC system over an 18-month period at Seattle Veterans Administration Center were examined in this study. Of 7,783 cultures obtained, 624 classified as true positives. Patients group had between 20 and 60 ml of blood drawn per separated into 10-ml aliquots incubation. Analysis results stratified cultured volume time interval specimen collection accorded yield advantage to maximal amounts tested. No was observed...
Oral submucous fibrosis (OSF) is a potentially malignant disorder. Current studies have shown that chewing areca nut considered the main cause of OSF, and endothelial-mesenchymal transformation (EndMT) participates in occurrence development fibrotic lesion. However, specific molecular mechanisms treatments remain unclear. Here, we report mechanism arecoline-induced EndMT importance this also identify potential therapeutics for decreasing OSF incidence. We demonstrate overexpression...
Emerging evidence indicates that natural killer (NK) cells may contribute to liver injury in patients with hepatitis B virus (HBV) infection. Because HBV infection progresses through various disease phases, the cytolytic profiles of peripheral and intrahepatic NK HBV-infected remain be defined. In this study, we comprehensively characterized a cohort individuals, investigated their impact on pathogenesis during chronic The study population included 34 immune-clearance (IC) patients, 36...
Abstract Immune checkpoint blockade (ICB) has become the standard of care for several solid tumors. Multiple combinatorial approaches have been studied to improve therapeutic efficacy. The combination antiangiogenic agents and ICB demonstrated efficacy in cancers. To mechanistic understanding synergies with these treatment modalities, we performed screens sera from long-term responding patients treated ipilimumab bevacizumab. We discovered a high-titer antibody response against EGF-like...
Abstract It is widely acknowledged that Carbon Capture, Utilization, and Storage (CCUS) constitutes an indispensable component in the global endeavor to mitigate carbon emissions by 15-20%, thereby aligning with 1.5°C (2.7°F) target set for 2050. Despite substantial governmental support, such as 45Q, progress CCUS development infrastructure remains sluggish, primarily attributed initial capital outlays involved. A significant proportion of these costs can be utilization costly...
Objective: To construct and validate a predictive model for pathological complete response (pCR) in patients with locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy. Methods: This retrospective observational study included 595 stage T2-4 (or) N+M0 LARC diagnosed the Cancer Hospital of Chinese Academy Medical Sciences Fourth Hebei University who had no metastases, tolerated therapy, completed undergone radical surgery therapy. The training set comprised 299 admitted to...
To investigate humanistic practice ability of nurses in a general hospital Hunan Province and analyze the factors affecting their practices to provide evidence for interventions improve nurses.A total 1196 were surveyed using self-designed questionnaire nurse assessment scale abilities care practice, psychological adjustment, interpersonal communication, self-management, ethics legal practice. Univariate multivariate analyses performed analysis nurses.The score was 105.69±16.45 (the full...
Echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) gene rearrangements and epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) have been intensively studied. The objective of this study was to determine the clinicopathological characteristics genotype-specific subsets patients with NSCLC help ensure optimal identification whose tumors harbor these two driver mutations. incidence ALK investigated 763 specimens by...
Abstract With the successful development of immune checkpoint blockade, there remains continued need to improve efficacy and decrease toxicities. The addition granulocyte–macrophage colony-stimulating factor (GM-CSF) ipilimumab has previously demonstrated both an improvement in incidence high-grade adverse events. ICOS+CD4+ or ICOS+CD8+ peripheral blood T cells are significantly greater patients treated with plus GM-CSF than alone. To better understand effects on inducible T-cell...
Abstract In-situ bioremediation technology is considered an ideal and environment-friendly approach for the largescale treatment of petroleum-contaminated soil. Most earlier studies on have focused biostimulation techniques, which can enhance biodegradation capabilities indigenous bacteria, rather than bioaugmentation involving introduction exogenous microorganisms. Additionally, contaminated soil sites typically contain both natural artificial fractures. These fractures serve as...
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<div>Abstract<p>With the successful development of immune checkpoint blockade, there remains continued need to improve efficacy and decrease toxicities. The addition GM-CSF ipilimumab has previously demonstrated both an improvement in incidence high-grade adverse events. ICOS+CD4+ or ICOS+CD8+ peripheral blood T cells are significantly greater patients treated with plus than alone. To better understand effects on ICOS clinical outcomes, relative roles identified soluble...
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