(1) Background: The identification of patients at risk for hepatitis B and C viral infection is a challenge the clinicians public health specialists. aim this study was to evaluate compare predictive performances four machine learning-based models prediction HBV HCV status. (2) Methods: This prospective cohort screening evaluated adults from North-Eastern South-Eastern regions Romania between January 2022 November who underwent in their family physician’s offices. patients’ clinical...

(1) Background: Prenatal care providers face a continuous challenge in screening for intrauterine growth restriction (IUGR) and preeclampsia (PE). In this study, we aimed to assess compare the predictive accuracy of four machine learning algorithms predicting occurrence PE, IUGR, their associations group singleton pregnancies; (2) Methods: This observational prospective study included 210 pregnancies that underwent first trimester screenings at our institution. We computed performance...

Background/Objectives: There is a constant need to improve the prediction of adverse neurodevelopmental outcomes in growth-restricted neonates who were born prematurely. The aim this retrospective study was evaluate predictive performance three-layered neural network for determined at two years age by Bayley Scales Infant and Toddler Development, 3rd edition (Bayley-III) scale prematurely infants affected intrauterine growth restriction (IUGR). Methods: This observational included premature...

Background and Objectives: Fetal ovarian cysts (FOCs) are a very rare pathology that can be associated with maternal-fetal neonatal complications. The aim of this study was to assess the influence ultrasound characteristics on FOC evolution therapeutic management. Materials Methods: We included cases admitted our perinatal tertiary center between August 2016 December 2022 prenatal or postnatal evaluation indicative FOC. retrospectively analyzed pre- medical records, sonographic findings,...

(1) Background: SARS-CoV-2 infection during pregnancy could determine important maternal and fetal complications. We aimed to prospectively assess placental immunohistochemical changes, immunophenotyping alterations, outcomes in a cohort of patients with COVID-19; (2) Methods: 52 pregnant admitted tertiary maternity center between October 2020 November 2021 were segregated into two equal groups, depending on the presence infection. Blood samples, fragments umbilical cord, amniotic membranes,...

(1) Background: Retinopathy of prematurity (ROP) can cause severe visual impairment or even blindness. We aimed to assess the hematological risk factors that are associated with different stages ROP in a cohort preterm newborns, and compare clinical characteristics therapeutic interventions between groups. (2) Methods: This retrospective study included 149 newborns from tertiary maternity hospital Romania January 2018 December 2018, who were segregated into: Group 1 (with ROP, n = 59...

(1) Background: Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) have in common a deficient maternal adaptation to the semi-allogeneic fetus, which killer immunoglobulin-like receptor (KIR) family expressed by natural (NK) cells play an important role. The aim of this study was evaluate influence KIR haplotype on reproductive outcomes after single embryo transfer IVF cycles patients with RPL RIF. (2) Methods: Patients RIF who presented at Origyn Fertility Center from...

(1) Background: Urinary tract infections (UTIs) are an important cause of perinatal and maternal morbidity mortality. The aim this study was to describe compare the main pregnancy outcomes among pregnant patients with complicated uncomplicated UTIs; (2) Methods: This retrospective included 183 who were evaluated for UTIs urosepsis in Urology Department ‘C.I. Parhon’ University Hospital, followed up at a tertiary maternity hospital- ‘Cuza-voda’ from Romania between January 2014 October 2023....

(1) Background: This study aimed to outline the antioxidant, antitumoral, and cytotoxic proprieties of various types Perilla frutescens extracts obtained from leaves species. (2) Methods: We determined total polyphenols, flavonoids anthocyanins contents, as well in vitro actions three ethanolic (E1, E2, E3) acetone: ethanol (A1, A2, A3) according standardized procedures. (3) Results: found that had highest phenol concentrations. The concentration was not statistically different between...

(1) Background: Neonatal early-onset sepsis (EOS) is associated with important mortality and morbidity. The aims of this study were to evaluate the association between serum hematological biomarkers early onset neonatal in a cohort patients prolonged rupture membranes (PROM) calculate their diagnostic accuracy. (2) Methods: A retrospective was conducted on 1355 newborns PROM admitted January 2017 March 2020, who divided into two groups: group A, ≥ 18 h, B, ROM < h. Both groups further...

The current pandemic of COVID-19 infection worries the world, due to high morbidity and mortality. Various strategies for control, including nutritional interventions, have been considered, given extremely rapid spread disease, lack specific effective safe antiviral treatment difficulty having a vaccine in near future. Vitamin C, long known its antioxidant anti-infective effects, has analyzed from perspective biochemical mechanisms with potential benefits patients severe infection. Favorable...

Background and Objectives: Urinary tract infections (UTIs) are an important cause of perinatal maternal morbidity mortality. The aim this study was to describe compare the main pregnancy outcomes among pregnant patients with complicated uncomplicated UTIs; Materials Methods: This retrospective included 183 who were evaluated for UTIs urosepsis in Urology Department ‘C.I. Parhon’ University Hospital, followed up at a tertiary maternity hospital—‘Cuza-voda’ from Romania between January 2014...

: Intra/postpartum hemorrhage stands as a significant obstetric emergency, ranking among the top five leading causes of maternal mortality. The aim this study was to assess predictive performance four machine learning algorithms for prediction postpartum and intrapartum hemorrhage.

Background and Objectives: Preterm birth (PTB) is associated with important neonatal mortality morbidity. The aim of this study was to retrospectively evaluate the average treatment effects on treated efficacity various therapeutic interventions for PTB in a cohort patients singleton pregnancies short cervical lengths. Materials Methods: This observational retrospective included 1146 at risk that were segregated into following groups: intravaginal progesterone (group 1), Arabin pessary 2),...

(1) Background: Cervical elastography is a new concept that could allow clinicians to assess cervical consistency in various clinical scenarios. We aimed evaluate the predictive performance of strain ratio (SR) at level internal os, either individually or combination with other parameters, prediction spontaneous preterm birth (PTB) gestational ages. (2) Methods: This prospective study included 114 pregnant patients high-risk profile for PTB who underwent during second trimester. Clinical and...

1) Background: The screening of preeclampsia (PE) and intrauterine growth restriction (IUGR) represents a constant challenge for obstetricians. aim this study was to determine compare the predictive performance 4 machine learning-based algorithms prediction PE, IUGR, their association in cohort singleton pregnancies; (2) Methods This prospective conducted at tertiary maternity hospital Romania, included 210 pregnancies that underwent first trimester screening. We clinical paraclinical data...

(1) Background: Neonatal early-onset sepsis (EOS) is associated with important mortality and morbidity. The aims of this study were to evaluate the association between serum biomarkers early onset neonatal in a cohort patients prolonged rupture membranes (PROM), calculate their diagnostic accuracy. (2) Methods: A retrospective was conducted on 1355 newborns PROM admitted January 2017 March 2020, who divided two groups: group A, ≥ 18 hours B, < hours. Both groups further split into...

In this study is presented the result obtained for treatment of waste water from medical sector using membrane filtration system. Polyethersulfone (PES) membranes were Dimethylformamide DMF like solvent, with different concentration to determine rejection variation dyes. Membranes by immersion precipitation method and permeation properties determined dead end technique. The results show that can improved reduce cost sector. Using solvent a smaller polymer have good in comparison other solvents.

A significant part of the research and production activities is represented in field bioengineering by biomaterials used hard tissue restorations. They are great interest dental science, intending to improve technological aspects, monitoring their biological responses living organisms, but also redesign economic beginning with choice raw materials. In present work, light-curing composite were made from a polymer matrix consisting specific concentrations bisphenol A-glycidyl methacrylate base...

(1) Background: This study aimed to outline the antitumoral, antioxidant, and cytotoxic proprie-ties of various types Perilla frutescens extracts obtained from leaves species; (2) Methods: We determined total polyphenols, flavonoids anthocyanins contents, as well in vitro actions 3 ethanolic (E1, E2, E3) ethanol: acetone (A1, A2, A3) according standardized procedures; (3) Results: found that had higher phenol concentrations (p= 0.002). Flavonoids were not statistically different between two...

A controversy persists over whether or not the type of embryo transfer (ET) influences reproductive outcomes. This study aimed to evaluate outcomes pregnant patients undergoing their first in vitro fertilization procedure and explore influence various KIR genotypes on these

The emergence of the new coronavirus SARS-CoV-2, at end 2019, triggered worst pandemic last century, called COVID-19. Unlike SARS-CoV-1, which developed as an epidemic in 1996 but was limited to Asia, SARS -CoV-2 spread rapidly millions people worldwide, with a high mortality rate. Deciphering structure viral S and SARS-CoV genome-2 allowed identification targets for vaccination, most important being protein S. development -COVID-19 vaccines is based on use innovative biotechnologies, some...