A5032594200- Viral Infections and Immunology Research
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Whipple's Disease and Interleukins
- RNA and protein synthesis mechanisms
- Herpesvirus Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- RNA regulation and disease
- Cytomegalovirus and herpesvirus research
- Ocular Diseases and Behçet’s Syndrome
- Rabies epidemiology and control
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Retinal and Optic Conditions
ICMR-National Institute of Virology
2007-2025
Command Hospital
2022
The main route of the transmission severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are through pathways and close contact human-to-human. While information about other modes is comparatively less, some published literature supporting likelihood a fecal-oral mode has been accumulating. diagnosis SARS-COV-2 infected cases based on real-time reverse transcription-PCR (RT-PCR). fecal excretion reported frequently, however, role viral load with severity disease not yet clear. Our...
A hospital-based surveillance was undertaken between May 2005 and April 2006 to elucidate the contribution of Chandipura virus (CHPV) acute viral encephalitis cases in children, seroconversion recovered compare seroprevalences anti-CHPV IgM N antibodies areas reporting with those without any case encephalitis. During this period, 90 were hospitalized pediatric wards Mahatma Gandhi Memorial (MGM) Hospital, Warangal. There 49 deaths (Case Fatality Rate, i.e., CFR 54.4%). Clinical samples...
Outbreaks of HFMD in children aged <5 years have been reported worldwide and the major causative agents are Coxsackievirus (CV) A16, enterovirus (EV)-A71 recently CVA6. In India, is a disease that not commonly reported. The purpose study was to identify type(s) associated with large outbreak Hand, foot, mouth during COVID-19 pandemic 2022. Four hundred twenty five clinical samples from 196-suspected cases were collected different parts country. This finding indicated emergence CVA6 along...
Acute Hemorrhagic Conjunctivitis (AHC) is primarily caused by viral infections, with Coxsackievirus A-24v (CV-A24v) being a significant culprit. Enteroviruses, including CV-A24v, are responsible for global AHC outbreaks. Over time, CV-A24v has evolved, and genotype IV (GIV) become the dominant strain. This study focused on examining genetic features evolutionary trends of recent outbreak 2023 in India. Researchers isolated strains from ocular swabs confirmed presence using reverse...
Coxsackievirus-A6 (CV-A6) is responsible for more severe dermatological manifestations compared to other enteroviruses such as CV-A10, CV-A16, and EV-A71, causing HFMD in children adults. Between 2005 2007, the recombinant subclade D3/RF-A started expand globally, a CV-A6 pandemic started. The study aimed conduct whole-genome sequencing (WGS) of an isolated strain from currently circulating cases India 2022. Gene-specific RT-PCR were used perform molecular characterization virus....
Abstract The present study highlights pathogenesis and molecular aspects of Coxsackie virus A‐16 (CVA‐16) strains isolated from hand, foot, mouth disease (HFMD) cases India using a neonatal mice model. ICR were intraperitoneally inoculated with CVA‐16/311 strain HFMD cases. Mice developed hind forelimb paralysis on day 3 post infection. Histopathological observations limb muscles showed necrosis, dissolution muscle fiber cells, infiltration inflammatory marked dilated ventricle, hemorrhages,...
Hand, foot and mouth disease (HFMD) is a common childhood infectious disease, caused by enteroviruses (EVs), which can present with typical or atypical lesions. The illness self-limiting, but it also have serious complications. Since 1997, HFMD infections become endemic increased to epidemic proportions across the Asia Pacific region, including India. Coxsackievirus-A16 (CV-A16) outbreaks occurred in India from 2005 onwards, although clinical symptoms were noticeably different during this...
Hand, Foot and Mouth disease (HFMD) is a contagious pediatric viral caused due to enteroviruses (EV) of the family Picornaviridae. Cases HFMD were reported from tertiary care health centre, Udhampur, (Jammu Kashmir), Northern India. The present study highlights clinical molecular virological aspects cases.Cases during August 2016-September 2017, clinically diagnosed as all age groups included. Clinical, Biochemical virology compared. Clinical samples (n = 50) such vesicle swab, buccal...
Hand, foot and mouth disease (HFMD) is a paediatric associated with enteroviruses (EVs). Among EVs, coxsackievirus A-16 (CVA-16) strain currently in circulation causing outbreaks India. Neonatal mice (Institute of Cancer Research) strains were infected CVA-16 isolated from HFMD patients to conduct pathological molecular studies. Infected organs harvested as per time points. A real-time polymerase chain reaction was used for qualitative estimation viral RNA organ tissues mice. Skeletal...