- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Congenital Anomalies and Fetal Surgery
- SARS-CoV-2 and COVID-19 Research
- Vibrio bacteria research studies
- Antifungal resistance and susceptibility
- Viral gastroenteritis research and epidemiology
- Parasites and Host Interactions
- Cystic Fibrosis Research Advances
- Antimicrobial Resistance in Staphylococcus
- Tuberculosis Research and Epidemiology
- Fungal Infections and Studies
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Pneumocystis jirovecii pneumonia detection and treatment
- Parasite Biology and Host Interactions
- Infection Control in Healthcare
- Infections and bacterial resistance
- Plant Pathogenic Bacteria Studies
- Parvovirus B19 Infection Studies
Sher-i-Kashmir Institute of Medical Sciences
2016-2025
University of Kashmir
2008
To find the effectiveness of essential oil lemongrass for treatment pathogenic organisms. Lemongrass was investigated activity against Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), subtilis subtilis), Escherichia coli (E. coli), Klebsiella pneumoniae (K. pneumoniae) and Pseudomonas aeruginosa (P. aeruginosa), using Agar Diffusion Method Broth Dilution Method. Minimum inhibitory concentration (MIC) minimum bactericidal (MBC) were determined by The antibiotic susceptibility...
In Brief Background: As fungal endophthalmitis is an emerging challenge, the study was carried out to determine prevalence and spectrum of agents causing from a single center, identify risk factors, correlate clinical course illness with involved. Methods: The microbiological records all diagnosed during January 1992 through December 2005 at tertiary center in India were reviewed retrospectively. During this period, treatment protocol patients pars plana vitrectomy, instillation intravitreal...
Background Cystic echinococcosis (CE) caused by the Echinococcus granulosus, is a major public health problem worldwide, including India. The different genotypes of E. granulosus responsible for human hydatidosis have been reported from endemic areas throughout world. However, genetic characterization infecting population in India lacking. aim study was to ascertain genotype(s) parasite North Methodology/Principal Findings To transmission patterns genotypic analysis performed on hydatid...
The genetic diversity and population genetics of the Echinococcus granulosus sensu stricto complex were investigated based on sequencing mitochondrial DNA (mtDNA). Total 81 isolates hydatid cyst collected from ungulate animals different geographical areas North India identified by cytochrome c oxidase subunit1 (coxi) gene. Three genotypes belonging to E. (G1, G2 G3 genotypes). Further nucleotide sequences (retrieved GenBank) for coxi gene seven populations covering 6 continents, compared...
The number of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) cases is increasing in India. This study looks upon the geographic distribution virus clades and variants circulating different parts India between January August 2020. NPS/OPS from representative positive states union territories were collected every month through VRDLs country analyzed using next-generation sequencing. Epidemiological analysis 689 SARS-CoV-2 clinical samples revealed GH GR to be predominant northern...
Over time, COVID-19 testing has significantly declined across the world. However, it is critical to monitor virus through surveillance. In late 2020, WHO released interim guidance advising use of existing Global Influenza Surveillance and Response System (GISRS) for integrated surveillance influenza SARS-CoV-2.In July 2021, we initiated a pan-India SARS-CoV-2 geographically representative network Virus Research Diagnostic Laboratories (VRDLs) 26 hospital laboratory sites 70 community sites....
There is a paucity of literature regarding the microbial etiology community-acquired pneumonia (CAP) in India. The current study was aimed to hospitalized adults with CAP.The conducted 700-bedded North Indian hospital. Consecutive admitted CAP over period 2 years from 2013 2015 were recruited for study, and apart clinical evaluation underwent various microbiological studies form blood culture, sputum urinary antigen pneumococcus Legionella, serology Mycoplasma Chlamydia real-time reverse...
Outbreaks of HFMD in children aged <5 years have been reported worldwide and the major causative agents are Coxsackievirus (CV) A16, enterovirus (EV)-A71 recently CVA6. In India, is a disease that not commonly reported. The purpose study was to identify type(s) associated with large outbreak Hand, foot, mouth during COVID-19 pandemic 2022. Four hundred twenty five clinical samples from 196-suspected cases were collected different parts country. This finding indicated emergence CVA6 along...
Metallo-beta-lactamases (MBL) producing Pseudomonas aeruginosa strains are responsible for several nosocomial outbreaks in tertiary care centers across the world. It is well known that poor outcome occurs when patients with serious infections due to MBL producing organisms treated antibiotics which organism completely resistant. Therefore, detection of these producing P. aeruginosa is crucial optimal treatment critically ill patient’s and prevent spread resistance. Current study was...
Background Echinococcosis is a human and animal health problem in many endemic areas worldwide. There are numerous reports hospital-based studies from Kashmir, North India, yet there has been no epidemiological study conducted the apparently area for hydatidosis. This was designed to determine seroprevalence of hydatid infection Kashmir Valley find out association risk factors acquisition this infection. Methodology Fourteen hundred twenty-nine samples were collected different districts...
Abstract During March to June 2021 India has experienced a deadly second wave of COVID-19 with an increased number post-vaccination breakthrough infections reported across the country. To understand possible reason these breakthroughs we collected 677 clinical samples (throat swab/ nasal swabs) individuals who had received two doses (n=592) and one dose (n=85) vaccines (Covishield Covaxin,) tested positive for COVID-19, from 17 states/Union Territories These cases were telephonically...
Background: Rickettsial diseases were reported from Kashmir, India, in the early 20th century. Since then, limited research was carried that has resulted a significant gap understanding these diseases. This study conducted to find out prevalence and diversity of rickettsial this region. Methods: Blood sample 476 patients collected. Enzyme-linked immunosorbent assay done for detection IgM IgG, immunofluorescence endpoint titer determination. Nested polymerase chain reaction performed spotted...
Considerable information is available about the acute respiratory symptoms of influenza A and B. However, rarely, these viruses can adversely affect cardiovascular system. Few cases pericardial effusion cardiac tamponade due to Influenza virus have been reported. To best our knowledge, we present first case a 23-year-old unvaccinated woman having concurrent B infection manifesting as tamponade. The patient was treated with oseltamivir 75 mg, resulting in significant clinical improvement....
Abstract Serological diagnosis of cystic echinococcosis (CE) is usually made by detecting specific antibodies in serum samples. However, collection blood samples difficult and may be hazardous unsafe. Thus, it important to assess alternative simple methods sampling body fluids that give similar results. Saliva urine have been suggested as possible alternatives detect for the various diseases. To best our knowledge, there has no previously published study regarding detection CE-specific...
Spinal epidural abscess, although an uncommon disease, often correlates with a high morbidity owing to significant delay in diagnosis.In prospective 5-year study, the clinical and magnetic resonance (MR) findings, treatment protocols, microbiology, neurological outcomes were analyzed for 27 patients spinal abscess.Patients typically middle-aged underlying diabetes presented lumbar abscesses. Those undergoing surgical intervention >36 h after onset of symptoms had poor outcomes.Early...
Abstract Objective: The burden of healthcare-associated infections (HAIs) is higher in low- and middle-income countries, but HAIs are often missed because surveillance not conducted. Here, we describe the identification response to a cluster Burkholderia cepacia complex (BCC) bloodstream (BSIs) associated with high mortality surgical ICU (SICU) that joined an HAI network. Setting: A 780-bed, tertiary-level, public teaching hospital northern India. Methods: After detecting BCC SICU, cases...
Soil-transmitted helminths (STHs) remain a major threat to the health of children throughout world, mostly in developing nations. The aim present study was determine any relationship between STHs and hemoglobin status school Kashmir Valley (India). Stool blood samples were collected from 382 male female age group 5-15 yr all 6 districts Valley. Finger-prick used collect hemoglobin, which then measured on-site by Sahli's acid hematin method; stool processed using both simple smear zinc...
Acute undifferentiated febrile illness (AUFI) is one of the most daunting challenges a physician faces in such settings. Among AUFI, rickettsial infections are common and related (such as anaplasmosis, ehrlichiosis, Q fever) which caused by an unusual type bacteria that can live only inside cells another organism. The present study was therefore planned with objective to estimate prevalence infection among patients fever determine any association socio-demographic characteristics...
Candidaemia is a potentially life-threatening emergency in the intensive care units (ICUs). Surveillance using common protocols large network of hospitals would give meaningful estimates burden candidaemia and central line associated low resource settings. We undertook this study to understand epidemiology multiple ICUs India, leveraging previously established healthcare-associated infections (HAI) surveillance network. Our aim was also assess impact that pandemic COVID-19 had on rates...
Candida dubliniensis is a pathogenic species which shares many phenotypic features with albicans. These similarities have caused significant problems in the identification of C. an average clinical mycology laboratory. Several phenotypic-based tests been developed to distinguish albicans from but none has demonstrated being sufficient alone for accurate differentiation two species.To facilitate these species, we evaluated utility novel medium 'Hypertonic Xylose Agar Medium' (HXAM).A total...