A5100389914- MicroRNA in disease regulation
- Cancer, Hypoxia, and Metabolism
- Endoplasmic Reticulum Stress and Disease
- Circular RNAs in diseases
- Ubiquitin and proteasome pathways
- Ginseng Biological Effects and Applications
- Plant Reproductive Biology
- Tryptophan and brain disorders
- Hormonal Regulation and Hypertension
- Cancer-related molecular mechanisms research
- Autophagy in Disease and Therapy
- Plant-Microbe Interactions and Immunity
- Acute Myeloid Leukemia Research
- Inflammasome and immune disorders
- Protein Interaction Studies and Fluorescence Analysis
- RNA Interference and Gene Delivery
- Medicinal plant effects and applications
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Kruppel-like factors research
- Neuroscience and Neuropharmacology Research
- Photosynthetic Processes and Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Flavonoids in Medical Research
- Retinoids in leukemia and cellular processes
Fuwai Yunnan Cardiovascular Hospital
2025
China Pharmaceutical University
2015-2024
Fuyang City People's Hospital
2024
Anhui Agricultural University
2023
Ministry of Agriculture and Rural Affairs
2023
The Synergetic Innovation Center for Advanced Materials
2020
Nanjing Agricultural University
2020
Second Military Medical University
2016
Changhai Hospital
2016
Nanjing University of Chinese Medicine
2015
Many neuroprotective approaches targeting neurons in animal models fail to provide benefits for the treatment of ischemic stroke clinic and glial cells have become targets some basic studies. Baicalin has effects but mechanisms related are not revealed. This study investigated whether how baicalin can combat excitotoxicity via protecting functions astrocytes early stage ischemia/reperfusion (I/R) insult by focusing on glutamine synthetase (GS). The role was explored primary exposed...
DNA and Cell Biology officially retracts the paper entitled, “Molecular Mechanisms of Disease Full Access miR-106a-5p Suppresses Proliferation, Migration, Invasion Osteosarcoma Cells by Targeting HMGA2,” Qian-Yun He, Guang-Chao Wang, Hao Zhang, Da-Ke Tong, Chen Ding, Kang Liu, Fang Ji, Xiongbai Zhu, Shengwu Yang. Biol, 35(9) 506-520; DOI: 10.1089/dna.2015.3121, due to suspicion scientific misconduct. The corresponding author, Dr. contacted journal via email, requested a correction be made...
Diverse functions of microRNAs have been investigated in tumorigenesis osteosarcoma (OS), involving the regulation proliferation, invasion, migration, apoptosis and drug resistance. MiR-367 was found to be an oncogene increased OS. However, function miR-367 resistance OS cells is still unknown. In this study, we that up-regulated tissues cell cultures. Meanwhile, treatment with adriamycin (ADR) induced upregulation miR-367. Notably, KLF4 demonstrated a direct target by gene reporter assay,...
Rare ginsenosides are found in ginseng and notoginseng, two medicinal plants widely used China for treatment of cardiovascular diseases type 2 diabetes. However, their pharmacological studies regarding myocardial fuel metabolism insulin signaling not clear.To explore the effect a rare ginsenoside-standardized extract (RGSE), derived from steamed on cardiac signaling.We palmitic acid (PA) to treat H9c2 cells vitro high fat diet (HFD) mice induce resistance vivo.In vitro, differentiated were...
Gilteritinib is a commonly used targeted drug for acute myeloid leukemia (AML), but the emergence of gilteritinib resistance greatly reduces therapeutic effect. RING finger protein 38 (RNF38), with Finger domain and E3 ubiquitin ligase activity, has been implicated in tumorigenesis resistance. However, role mechanism RNF38 AML remains unclear. Normal cells were treated to construct gilteritinib-resistant (MV4-11/Gilteritinib MOLM-13/Gilteritinib). CCK8 assay, TUNEL staining EdU assay assess...
VOLUME 296 (2021), ARTICLE NUMER 100382 Fig. 9A was inadvertently published without the bars in bar graph. The corrected graph is below. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders activation cancerJournal Biological ChemistryVol. 296PreviewTopoisomerase IIβ-binding protein 1 (TopBP1) involved cellular replication among other functions and known to activate during replicative stress. TopBP1 also expressed at high levels many cancers. However, impact...