Luana C. Mangeth

ORCID: 0009-0007-5076-1376
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About
Contact & Profiles
Research Areas
  • Mosquito-borne diseases and control
  • Nerve injury and regeneration
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Extracellular vesicles in disease

Universidade Federal do Rio de Janeiro
2024

Neutrophils interact with Leishmania when the sandfly vector inoculates these parasites in host saliva and promastigotes-derived extracellular vesicles (EVs). It has been shown that this co-injection induces inflammation exacerbates leishmaniasis lesions. EVs are a heterogeneous group of released by cells play crucial role intercellular communication. among first to release neutrophil traps (NETs) ensnare kill promastigotes. Here, we show amazonensis induce NET formation identify molecular...

10.1093/jleuko/qiae196 article EN Journal of Leukocyte Biology 2024-09-06
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