A5101782195- Peptidase Inhibition and Analysis
- Colorectal Cancer Screening and Detection
- Lung Cancer Research Studies
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Neuroendocrine Tumor Research Advances
- MicroRNA in disease regulation
- Hepatitis B Virus Studies
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical studies and practices
- Chromatography in Natural Products
- Liver Disease Diagnosis and Treatment
- Cancer Mechanisms and Therapy
- Cervical Cancer and HPV Research
- Cancer Research and Treatments
- Flavonoids in Medical Research
- Antibiotic Use and Resistance
- RNA modifications and cancer
- Synthesis and bioactivity of alkaloids
- Intracerebral and Subarachnoid Hemorrhage Research
- Ubiquitin and proteasome pathways
- Virus-based gene therapy research
- Berberine and alkaloids research
- Acute Ischemic Stroke Management
- Hepatitis C virus research
XinHua Hospital
2014-2025
Shanghai Jiao Tong University
2016-2025
West China Medical Center of Sichuan University
2023-2024
Importance Timely analysis of cancer incidence trends is crucial for prevention and control, which a public health priority in China. Objective To estimate 32 cancers China from 1983 to 2017 project changes 2032, assessing distinct due risk factors an aging population. Design, Setting, Participants This population-based cohort study used data the Cancer Incidence Five Continents database (1983-2017). New cases were collected. Data analyzed October 15, 2023, May 23, 2024. Main Outcomes...
China accounted for 45.3% of new cases primary liver cancer (PLC) worldwide in 2020. While variations PLC incidence between different regions and decreasing overall have been reported, patterns not thoroughly explored by region. We examined the nearly status temporal trends geographical project future trends. The age-standardized rate (ASR) was estimated 1978 to 2012 gender China. Age-period-cohort model adopted evaluate age birth cohort effects on trend five registries (Hong Kong, Shanghai,...
The aims of this study were to observe the apoptosis effects tetrandrine on human gallbladder carcinoma cell line (SGC-996), and explore its related mechanism.First, anti-proliferative activities SGC-996 cells determined by using MTT assays. Then, cycle changes detected flow cytometry analysis. was annexin V/propidium iodide double-staining assay. Detection mitochondrial membrane potential used validate ability inducing apoptosis. Finally, expressions apoptosis-related proteins (caspase-3,...
Abstract The long‐term incidence trends of 32 cancers in China remained unclear. Cancer statistics for young population were often presented aggregate, masking important heterogeneity. We aimed to assess the from 1983 2032, stratified by sex and age groups. Data on cancer 2017 extracted Incidence Five Continents Volumes VI–XII. age‐period‐cohort model was utilized birth cohort effects temporal China, while Bayesian project future 2018 2032. An increase is observed some such as thyroid kidney...
Abstract The majority of gallbladder cancer cases are discovered at later stages, which frequently leads to poor prognoses. Small-cell neuroendocrine carcinoma (GB-SCNEC) is a relatively rare histological type cancer, and its survival rate exceptionally low because greater malignant potential. In addition, the genomic landscape GB-SCNEC rarely considered in treatment decisions. We performed whole-genome sequencing on an advanced case GB-SCNEC. By analyzing data primary tissue (76.29X...
Objective To study the effects of sodium hydrogen exchange protein 1 (Na+/H+ ; NHE1)-specific inhibitor Cariporide on metastasis GBC-SD cells in vitro and to preliminarily explore potential anti-metastatic mechanism Cariporide.Methods The regulatory effect intracellular pH extracellular were analyzed by BCECF phenol red.The adhesion,migration,and invasion determined using cell-matrix adhesion assay,wound healing assay,and cell assay.Real-time PCR (RT-PCR) Western blot assay also used detect...