A5073491598- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- Reproductive biology and impacts on aquatic species
- Cancer-related molecular mechanisms research
- Ubiquitin and proteasome pathways
- Reproductive Physiology in Livestock
- Immunotherapy and Immune Responses
- Historical Gender and Feminism Studies
- Epigenetics and DNA Methylation
- Kruppel-like factors research
- Pregnancy and preeclampsia studies
- Hormonal and reproductive studies
- Cytokine Signaling Pathways and Interactions
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Northwest A&F University
2020-2024
Ministry of Agriculture and Rural Affairs
2020-2024
Semen cryopreservation has become an essential tool for conservation efforts of the giant panda (Ailuropoda melanoleuca); however, it is severely detrimental to sperm quality. Evidence shown that antioxidants have potential reverse cryopreservation-induced damage in sperm. The purpose this study was screen effective could retain quality during and determine optimal dose. Seven antioxidant groups, including resveratrol (RSV = 50 μM, RSV 100 150 μM), lycium barbarum polysaccharide (LBP 2...
Interferon tau (IFNT), a pregnancy recognition signal in ruminants, promotes the establishment of embryo implantation by inducing expression interferon-stimulated genes (ISGs) via Janus kinase/signal transducer and activator transcription (JAK/STAT) signaling pathway. However, precise regulatory mechanism IFNT goat remains largely unknown. In this study, we performed RNA sequencing endometrial epithelial cells (gEECs) with or without 20 ng/mL treatment. Differential comparison showed that...
Decidualization is a critical process for successful embryo implantation and subsequent placenta formation. The characterization physiological function of lncRNA during decidualization remain largely unknown. In the present study, we conducted RNA-sequencing analysis to compare gene expression between decidua days 6 8, normal pregnant endometrium (day 4). A total 2332 high-confidence putative transcripts were expressed. Functional clustering cis trans targets showed that differentially...
Abstract The endometrium plays an important role in the defence against invading pathogens, although mechanisms are not clear. UFMylation is a recently discovered novel ubiquitination‐like modification system that pivotal inflammation and immune response. purpose of this study was to investigate effects on lipopolysaccharide (LPS)‐induced inflammatory responses immortalized goat endometrial epithelial cells (gEECs). Ubiquitin‐fold modifier conjugating enzyme 1 (UFM1) DDRGK domain containing...
Abstract The global challenge of male infertility is escalating, notably due to the decreased testosterone (T) synthesis in testicular Leydig cells under stress, underscoring critical need for a more profound understanding its regulatory mechanisms. CREBZF, novel basic region‐leucine zipper transcription factor, regulates mouse vitro; however, further validation through vivo experiments essential. Our study utilized Cyp17a1‐Cre knock out CREBZF androgen‐synthesis and explored physiological...
Abstract Background: Semen cryopreservation has become an essential tool for the reproduction and long-term preservation of giant pandas (Ailuropoda melanoleuca). However, is severely detrimental to sperm quality, including motility, plasma membrane, acrosome integrity, mitochondrial activity. It necessary screen a effective antioxidants improvement quality. Eight groups were added freezing medium. Results: The results showed that lycium barbarum polysaccharide (LBP), Laminaria japonica...