To improve the clinical and microbiological outcomes of non-surgical mechanical periodontal therapy, adjunctive use antimicrobials has been utilized in treating moderate-to-severe periodontitis. In our study, retrospective design included previously collected health-related patient data, obtained from printed digital charts patients who received systemic or local antibiotic adjuncts to SI (subgingival instrumentation). A total 34 (diagnosed with generalized Stage III/IV periodontitis) met...

Novel nanotechnology based on herbal products aspires to be a high-performing therapeutic platform. This study reports the development of an original engineering carrier system that jointly combines pharmacological action Chelidonium majus and AuNPs, with unique properties ensure limitations imposed by low stability, toxicity, absorption, targeted prolonged release can overcome. The metabolite profile Romanian wild-grown contains total seventy-four phytochemicals belonging eight secondary...

Background and objectives: this study aims to evaluate the clinical microbiological effects of a single subgingival administration locally delivered antibiotic gel containing piperacillin plus tazobactam compare it with slow-release doxycycline (14%) placebo gel, following instrumentation (SI) in patients severe periodontitis. Materials methods: sixty-four diagnosed stage III–IV periodontitis were enrolled, randomly assigned into three groups, treated additionally (group A); B); C). The...

Research in the field of periodontal disease continues to focus on disease-associated microorganisms, as microbial plaque and host immune responses are considered be important causative factors, that highly responsible for progression this disease. The purpose article is compare reduction number specific periodontopathogens two test groups according different therapeutic approaches show possible differences. This based a prospective clinical study involving eighteen subjects with forty-four...

Background and Objectives: The aim of this study was to identify specific rhino- oropharyngeal microbiological pathogens as well associated comorbidities that favor SARS-CoV-2 infection corelate them. Materials Methods: This prospective clinical enrolled 61 patients (28 COVID-19-positive 33 controls) who were tested for other co-existence oral pathogenic microbiota. Results: A total 247 bacterial isolates identified in the cultures both groups. Viral hepatitis type more prevalent group (p =...

Objectives: This randomized, placebo-controlled, double-masked clinical trial aimed to evaluate the and microbiological efficacy of professional mechanical plaque removal (PMPR) with or without adjunctive application piperacillin plus tazobactam gel in treatment peri-implant mucositis (PiM) for up 6 months. Materials Methods: The study included 31 patients (bleeding on probing (BoP) > 1 at least one site baseline, absence bone loss compared a previous radiograph). After randomized...

In severe stages of periodontitis, conventional periodontal therapy and maintenance care are usually insufficient due to the viral bacterial etiology; thus, a mechanical approach alone may not be sufficient eliminate substantial portion subgingival pathogens, especially in deep sites. Background Objectives: This single-blind, randomized clinical trial aimed compare microbiological efficacy low-cost protocol using povidone–iodine sodium hypochlorite formulations as adjuncts non-surgical for...

Background and Objectives: This randomized, double-arm, multicentric clinical trial aims to compare the outcomes following treatment of suprabony periodontal defects using open flap debridement (OFD) with or without application hyaluronic acid (HA). Materials Methods: Sixty systemically healthy patients at least two teeth presenting were randomly assigned a 1:1 allocation ratio computer-generated tables into test (OFD + HA) control group (OFD). The main outcome variable was attachment level...

Gingivitis is a very common oral disease highly prevalent in adults that, if left untreated, can progress to periodontitis. It involves complex and slow interaction between the host response microbiome represented by dental plaque. The inflammation of gingiva associated with activation pathological angiogenesis existence high number newly formed blood vessels quantified as microvessel density (MVD). present study includes 51 gingival biopsies from patients different indexes (GI): GI = 0, n...

Aim of research was to evaluate and compare the clinical microbiological effects two different regimens amoxicillin (AMX) metronidazole (MTZ) combined with non-surgical periodontal therapy in patients chronic periodontitis (CP), identify antibiotic-resistant bacteria changes oxidative stress (OS). Forty-six generalized CP were randomly assigned group A [scaling root planing within 24 h (SRP) + placebo for 7 days), B [SRP AMX MTZ, both 500 mg three times daily (TID), 3 C TID, days)....

The objectives of this research were to compare, retrospectively, the clinical and radiographic modifications periodontal parameters peri-implant conditions analyze relationship between changes in over a mean follow-up period 7.6 years treated population with progressive/uncontrolled periodontitis at least one unaffected/minimally affected implant.Nineteen partially edentulous patients having 77 implants inserted, age 54.84 ± 7.60 years, matched for age, gender, compliance, smoking status,...

Background and Objectives: Even if they are cells of controversial origin (mesenchymal, perivascular, or fibroblastic), follicular dendritic (FDC) present in all organs. The aim this study was to establish the FDC expression pattern its interrelation with HPV 18 laryngeal squamous cell carcinoma (LSCC). Materials Methods: Fifty-six cases LSCC were evaluated by simple double immunostaining. following score used: 0 (negative few positive cells), 1 (10-30% 2 (30-50% 3 (over 50% cells). Results:...

: Less often employed as a rinsing solution for controlling oral biofilms, NaOCL was used in rinses at various concentrations steps 1 and 4 of periodontal therapy. The aim this study to quantitatively evaluate the biofilm-disruptive properties 0.2% NaOCl standardized using dedicated plaque-disclosing agents 3D scanning methods patients undergoing regular Guided Biofilm Therapy

Natal teeth, a rare dental anomaly present in about 1 every 2,000 to 3,500 live births, are teeth that either at birth (natal) or emerge within the first 30 days of life (neonatal). These usually appear front lower jaw and can lead issues such as breastfeeding challenges, tongue irritation, risk aspiration. While most occurrences isolated, some may be linked syndromes. Management options vary include monitoring, smoothing, extraction, depending on case. All instances require evaluation by...

HPV is an important oropharyngeal cancer cause, but it may have a role in other head and neck cancers? HPVpositive squamous cell carcinoma (HNSCC) epithelial-mesenchymal transition unclear. We included 38 cases: 20 laryngeal, 3 corresponding lymph nodes; 5 oropharyngeal, hypopharyngeal, 2 rhynopahryngeal, pharyngolaryngeal 1 naso-sinusal case. Immunoreactivity was positive nuclear expression cells, accordingly: score (10-30%), (30-50%) (]50%). HPV18 immunoexpression appeared 18 cases...

Maintaining the child's oral cavity in optimal health by preserving morpho-functional integrity of primary teeth, given influence they have on growth and development stomatognathic system is duty responsibility pedodontist. In addition to prevention, increased attention should be granted space control case early loss teeth support area, recommending use maintainers until eruption permanent successors, intercept appearance future anomalies.

Introduction In this research we tried to identify HPV infection as an important head and neck cancer cause, even though it is already oropharyngeal by evaluating E-cadherin expression. positive squamous cell carcinoma (HNSCC) epithelial-mesenchymal transition role still unclear.

Hemangiomas are a benign vascular proliferation, 50% of which located in the head and neck areas such as: lips, tongue, palate oral mucosa. Usually present at birth, hemangiomas rarely affect adults. In this paper we rare case giant tongue hemangioma affecting 73 year old male. Different treatment modalities radiotherapy, cryotherapy, laser therapy, medical treatment, injection sclerosing agents even embolization lingual artery were discussed. Due to its size, speaking, eating breathing...

Dental decay affects 4-86% of preschoolers (temporary dentition), and regarding mixed permanent dentition, the percentage affected children is between 27-86%. Caries lesions temporary teeth main dental problem that preschooler encounters, a to some extent with repercussions on development stomatognathic system. The use silver diamine fluoride (SDF), in treatment Early Chilhood (ECC) has been drawing increasing attention cause its antimicrobial effect species Streptococcus Mutans, Actinomyces...

Background: Visualization and calculation of the airway dimensions are important because an increase resistance may affect development dentofacial structures by altering breathing pattern growing patients.The aim this study is to shed light on resources provided cone -beam computed tomography in diagnosis possible physical barriers that reduce upper permeability presenting one case report.Material method: A patient clinically diagnosed with oral respiratory syndrome initially underwent a...