A5085897990- Oral microbiology and periodontitis research
- Periodontal Regeneration and Treatments
- Dental materials and restorations
- Dental Implant Techniques and Outcomes
- Oral Health Pathology and Treatment
- Endodontics and Root Canal Treatments
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Dental Radiography and Imaging
- Dental Health and Care Utilization
- HIV/AIDS oral health manifestations
- Dental Research and COVID-19
- Dental Erosion and Treatment
- Oral and gingival health research
- Streptococcal Infections and Treatments
- dental development and anomalies
- Oral and Maxillofacial Pathology
- Cleft Lip and Palate Research
- Dental Trauma and Treatments
- Selenium in Biological Systems
- Salivary Gland Disorders and Functions
- Systemic Sclerosis and Related Diseases
- Parkinson's Disease Mechanisms and Treatments
- Dental Anxiety and Anesthesia Techniques
- Infant Nutrition and Health
Iuliu Hațieganu University of Medicine and Pharmacy
2016-2025
University of Missouri–Kansas City
2025
University of Missouri Health System
2025
Spitalul Clinic Județean de Urgență Cluj-Napoca
2020-2024
Max Delbrück Center
2021-2024
Clinical Emergency Hospital Bucharest
2020-2023
University of Miami
2022
Lake Forest College
2018-2020
Northwestern Polytechnical University
2018-2019
The novelty of this study consists in the formulation and characterization three experimental dental composites (PM, P14M, P2S) for cervical lesion restoration compared to commercial Enamel plus HRi® - En (Micerium S.p.A, Avengo, Ge, Italy), G-ænial Anterior® (GC Europe N.V., Leuven, Belgium), Charisma® Ch (Heraeus Kulzer, Berkshire, UK). physio-chemical properties were studied, like degree conversion residual monomers cured samples using FTIR-ATR (attenuated total reflectance) HPLC-UV...
Selenium (Se) is an essential element for human and animal health. Biogenic selenium nanoparticles (SeNPs) by microorganism possess unique physical chemical properties biological activities compared with inorganic Se organic Se. The study was conducted to investigate the mainly of SeNPs Lactobacillus casei ATCC 393 (L. 393). results showed that L. transformed sodium selenite red size 50-80 nm, accumulated them intracellularly. 393-SeNPs promoted growth proliferation porcine intestinal...
Muscarinic acetylcholine receptors are prototypical G protein-coupled (GPCRs), members of a large family 7 transmembrane mediating wide variety extracellular signals. We show here, in cultured cells and murine model, that the carboxyl terminal fragment muscarinic M2 receptor, comprising regions 6 (M2tail), is expressed by virtue an internal ribosome entry site localized third intracellular loop. Single-cell imaging import isolated yeast mitochondria reveals M2tail, whose expression...
Lactococcus lactis (L. lactis) NZ9000, which has been genetically modified, is the most commonly used host strain for nisin regulated gene expression. Selenium (Se) an essential trace element in diet of humans and animals important maintenance health growth. Biosynthesized Se nanoparticles (SeNPs) that use microorganisms as a vehicle are uniquely advantages terms low costs, toxicity high bioavailability. This study was aimed at preparing novel functionalized SeNPs by L. NZ9000 through...
Background The aim of this study was to evaluate whether the combination enamel matrix derivative ( EMD ) with subepithelial connective tissue graft SCTG plus coronally advanced flap CAF would improve treatment outcomes Miller class I and II gingival recessions when compared same technique alone. Methods designed as a randomized, parallel, controlled, double‐blinded clinical trial. Forty‐two patients were randomly assigned in test group control ). Patients had at least one recession ≥ 2 mm....
(1) Background: This study investigated the influence of Bis-GMA, TEGDMA, UDMA, and two different polyethylene glycol (PEG)-containing, UDMO-based co-monomers on Young’s modulus flexural strength, degree methacrylate C=C double bond conversion residual monomer elution experimental dental resins. (2) Methods: Urethane methacrylate-based was synthesised via a radical chain growth polymerization mechanism using PEG in order to improve mechanical properties. Dental resins were formulated or UDMO...
(1) Background: This cross-sectional investigation appreciated the role of serum C-reactive protein (CRP), several hematologic-cell markers, and salivary inflammation-related molecules [calprotectin (S100A8/A9), interleukin-1β (IL-1β), kallikrein] to predict periodontitis in patients with atherosclerotic cardiovascular disease (ACVD), arrhythmia, or both. Also, we relationship between inflammatory burden periodontal destruction type cardiac pathology. (2) Methods: Demographic, behavioral...
Introduction: Green tea, GT, catechins, epigallocatechin-3-gallate (EGCG) and its polyphenol extract called Polyphenon E have been studied as potential anticancer agents. This systematic review evaluates the effect of GT exposure on cancer outcomes while focusing influence green tea dosage body mass index (BMI) modifiers. METHODS: A studies among PubMed, Scopus, Embase until June 2024, evaluating or patients was performed. Of 150 publications, five were included, comprising four RCTs one...
Objectives. Periodontal health can influence systemic and reproductive outcomes. In women undergoing pre-fertilization treatment, understanding the state of oral health, specifically bleeding on probing (BOP) index, factors such as hygiene practices, is essential. The objective present study to evaluate association between practices BOP index in a group preparing for fertilization treatments. Methods. includes 28 treatment whom gingival inflammation was recorded through periodontal...
Background/Objectives: Periodontitis, a prevalent chronic inflammatory disease affecting tooth-supporting structures, has been increasingly linked to systemic conditions such as diabetes mellitus (DM) and cardiovascular diseases (CVDs). This study aimed evaluate the periodontal status levels of dipeptidyl peptidase-4 (DPP-4) galectin-3 (Gal-3) in gingival crevicular fluid (GCF) patients with periodontitis, heart failure (HF), diabetes, exploring their potential biomarkers for association....
The identification of the associative relationships between ischemic stroke (IS) and risk factors such as advanced age periodontitis is essential to design real screening protocols address them using primary secondary preventive policies. This study primarily aimed evaluate diagnostic performance 2018 European Federation Periodontology/American Academy Periodontology (EFP/AAP) case definition in detecting against 2012 Centers for Disease Control Prevention/American (CDC/AAP) a group IS...
Abstract Resin composite‐based dental materials can leach certain components into the oral environment, causing potentially harmful gingival biological effect. Gingival tissue is a rich source of mesenchymal stem cells (MSCs) that easily accessible, and be used as complementary approach for investigation material biocompatibility. Using MSCs (gMSCs), present study aimed to investigate cytotoxicity two classes restorative (ormocers resin composites) restore class II cavities close margin, in...
Background and objectives: this study aims to evaluate the clinical microbiological effects of a single subgingival administration locally delivered antibiotic gel containing piperacillin plus tazobactam compare it with slow-release doxycycline (14%) placebo gel, following instrumentation (SI) in patients severe periodontitis. Materials methods: sixty-four diagnosed stage III–IV periodontitis were enrolled, randomly assigned into three groups, treated additionally (group A); B); C). The...
Injectable platelet-rich fibrin (iPRF) is a frequently used platelet concentrate for various medical purposes both in veterinary and human medicine due to the regenerative potential of hard soft tissues, also because its antimicrobial effectiveness. This vitro study was carried out assess cumulative antibiofilm effect iPRF functionalized with multifunctional glycoprotein, lactoferrin (Lf). Thus, ability potentiate cell proliferation tested on keratinocytes evaluated by CCK8 test. The...
The aim of this study was to analyze whether the mesenchymal stromal cells (MSCs) isolated from palatal tissue grafts harvested in order cover gingival recessions have basic characteristics stem cells. were processed using a special culture medium that stimulated development only undifferentiated cellular lines. Cells at passage 4 evaluated by flow cytometry examine expression specific surface markers and tested for multilineage differentiation capacity. These collected also investigated...
Abstract Objectives To evaluate the clinical, microbiological and enzymatic activity of a hydrophobic chlorhexidine‐based gingiva‐adhering gel containing herbal ingredients, compared with commercially available 1% chlorhexidine water‐soluble gel, during non‐surgical therapy moderate chronic periodontitis. Methods A total 34 subjects participated in this 6‐month blinded randomized parallel controlled trial ( ISRCTN 35210084). After scaling root planing SRP ), test group received by rubbing on...
Abstract The aim of the present study was to isolate human mesenchymal stem cells (MSCs) from palatal connective and periodontal granulation tissues comparatively evaluate their properties. MSCs were isolated using explant culture method. Adherence plastic, specific antigen makeup, multipotent differentiation potential, functionality, ultrastructural characteristics investigated. frequency colony-forming unit fibroblasts for palatal-derived (pMSCs) significantly higher than that...