A5101770680- Selenium in Biological Systems
- Liver Disease Diagnosis and Treatment
- Medical and Biological Ozone Research
- Cancer-related molecular mechanisms research
- Inflammasome and immune disorders
- Liver Diseases and Immunity
- Trace Elements in Health
- TGF-β signaling in diseases
- Hedgehog Signaling Pathway Studies
- Ferroptosis and cancer prognosis
- Reproductive Biology and Fertility
- Plant Molecular Biology Research
- Healthcare and Venom Research
- Plant tissue culture and regeneration
- Moringa oleifera research and applications
- Plant Gene Expression Analysis
- Reproductive Physiology in Livestock
- Sirtuins and Resveratrol in Medicine
- Dietary Effects on Health
- Phytochemistry and biological activities of Ficus species
- Advanced Biosensing Techniques and Applications
- Cardiac electrophysiology and arrhythmias
- Cancer, Stress, Anesthesia, and Immune Response
- Ocean Acidification Effects and Responses
- Venomous Animal Envenomation and Studies
Heilongjiang Bayi Agricultural University
2020-2025
Guizhou Electric Power Design and Research Institute
2024
PowerChina (China)
2024
Xinjiang Agricultural University
2022
Northwestern Polytechnical University
2018-2021
Jilin University
2019-2020
Daqing Normal University
2020
Chinese PLA General Hospital
2019-2020
Capital University
2019-2020
Capital Medical University
2019-2020
Selenium (Se) is an essential element for human and animal health. Biogenic selenium nanoparticles (SeNPs) by microorganism possess unique physical chemical properties biological activities compared with inorganic Se organic Se. The study was conducted to investigate the mainly of SeNPs Lactobacillus casei ATCC 393 (L. 393). results showed that L. transformed sodium selenite red size 50-80 nm, accumulated them intracellularly. 393-SeNPs promoted growth proliferation porcine intestinal...
Background: Selenium (Se) can exert antioxidative activity and prevent the body from experiencing oxidative injury. Biogenic Se nanoparticles (SeNPs) synthesized by probiotics possess relatively strong chemical stability, high bioavailability, low toxicity, this makes them potential supplements. Previously, we demonstrated that SeNPs Lactobacillus casei ATCC 393 alleviate hydrogen peroxide (H2O2)-induced human porcine intestinal epithelial cells' damage. However, antioxidant mechanism...
Lactococcus lactis (L. lactis) NZ9000, which has been genetically modified, is the most commonly used host strain for nisin regulated gene expression. Selenium (Se) an essential trace element in diet of humans and animals important maintenance health growth. Biosynthesized Se nanoparticles (SeNPs) that use microorganisms as a vehicle are uniquely advantages terms low costs, toxicity high bioavailability. This study was aimed at preparing novel functionalized SeNPs by L. NZ9000 through...
Postpartum cows experience lipolysis in adipose tissue due to negative energy balance (NEB), and accumulation of free fatty acids (FFA) leads metabolic stress tissue. Ferroptosis is a type cell death triggered by excessive buildup iron-dependent lipid peroxides, which involved the occurrence development various diseases nonruminants. However, it still unclear whether ferroptosis occurs ketotic regulatory mechanisms behind ferroptosis. Despite multiple studies demonstrating significant...
Abstract Objectives Chondrocyte proliferation and differentiation are crucial for endochondral ossification, but their regulatory mechanism remains unclear. The present study aimed to determine the physiological function of TGFβ1 signalling in antler chondrocytes explore its relationship with Notch, Shh Foxa. Materials methods Immunofluorescence, Western blot, MTS assay, flow cytometry, RNA interference real‐time PCR were used analyse mechanisms chondrocyte differentiation. Results TGFβ1,...
Ketosis is a major metabolic disorder of high-yielding dairy cows during the transition period. Although adaptations adipose tissue are critical for successful transition, beyond lipolysis, alterations within ketosis not well known. The objective this study was to investigate proteome healthy or ketotic postpartum gain insights into biological that may contribute disease outcomes. Adipose biopsy collected on 5 and at 17 (±4) d defined according clinical symptoms serum β-hydroxybutyrate...
Parkinson's disease (PD) is a progressive neurodegenerative disorder that closely associated with oxidative stress.
A voltage-gated, small, persistent Na + current ( I ) has been shown in mammalian cardiomyocytes. Hypoxia potentiates the that may cause arrhythmias. In present study, we investigated effects of n-3 polyunsaturated fatty acids (PUFAs) on HEK-293t cells transfected with an inactivation-deficient mutant (L409C/A410W) α-subunit (hH1 α human cardiac channels (hNav1.5) plus β 1 -subunits. Extracellular application 5 μM eicosapentaenoic acid (EPA; C20:5n-3) significantly inhibited . The late...
Dairy cows with metabolic disorder in peripartal period display high inflammatory levels. Adipose tissue is a major endocrine organ, which closely related to systemic inflammation. Retinoic acid (RA), an active metabolite of vitamin A, has shown potential therapeutic immunomodulatory properties. The objective the study was examine effect all-trans-RA (ATRA), biologically most on lipopolysaccharide (LPS)-induced bovine adipocytes responses and elucidate underlying mechanisms. Primary cultured...
Abstract Cold stimulation reduces the quality of animal products and increases mortality, causing huge losses to livestock industry in cold regions. Long non-coding RNAs (lncRNAs) take part many biological processes through transcriptional regulation, intracellular material transport, chromosome remodeling. Although stress-related lncRNAs have been reported plants, no research is available on characteristic functional analysis after stress rats. Here, we built a model firstly. Six SPF male...
Abstract Procyanidin B2 (PB2), a naturally occurring flavonoid abundant in wide range of fruits, has been shown to exert antioxidant, anti‐inflammatory and anticancer properties. However, the role PB2 prevention cold stimulation (CS)‐induced liver injury. The present study was undertaken determine effects on injury induced by its potential molecular mechanisms. results showed that treatment with significantly reduced CS‐induced alleviating histopathological changes serum levels alanine...
The beneficial effects of microecological agents have been widely proven. Se, which is a nutritionally essential trace element for humans and animals, incorporated into selenoproteins that wide range pleiotropic effects, ranging from antioxidant to anti-inflammatory effects.
Abstract The desert hedgehog (Dhh) is crucial for spermatogenesis and Leydig cell differentiation, but little known regarding its physiological function in cartilage. In this study, Dhh mRNA was abundant antler chondrocytes, where it advanced proliferation concomitant with accelerated transition from the G1 to S phase induced elevation of hypertrophic chondrocyte markers, Col X Runx2. Silencing Ptch1 resulted appreciable Smo accumulation enhanced rDhh stimulation Smo, whose impediment by...
Bottom protection (BP) is a commonly used engineering measure in river training. A 3D hydrodynamic numerical model established to study the influence of overall arrangements BP structures on hydraulic characteristics sharp bends. Under action group, maximum longitudinal flow velocity closer water surface vertically and concave bank laterally compared with no BP. The high shear stress zones riverbed at exit straight section bend do not occur. so-called primary circulation after apex gradually...
Abstract Background : Epimedii Folium(EF) is commonly used for treating bone fractures and joint diseases, but the potential hepatotoxicity of EF limits its clinical application. Our previous study confirms that could lead to idiosyncratic drug-induced liver injury (IDILI) hepatocyte apoptosis, mechanism remains unknown. Studies have shown NLRP3 inflammasome plays an important role in development various inflammatory diseases such as IDILI. Specific stimulus-induced activation may has been a...