A5011568520- Selenium in Biological Systems
- Trace Elements in Health
- Medical and Biological Ozone Research
- Advanced Photocatalysis Techniques
- Gut microbiota and health
- Antimicrobial Peptides and Activities
- Polysaccharides and Plant Cell Walls
- Gas Sensing Nanomaterials and Sensors
- Moringa oleifera research and applications
- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- Heme Oxygenase-1 and Carbon Monoxide
- Probiotics and Fermented Foods
- Ginseng Biological Effects and Applications
- Protein Hydrolysis and Bioactive Peptides
- High Altitude and Hypoxia
- Neuropeptides and Animal Physiology
- Biochemical effects in animals
- Helicobacter pylori-related gastroenterology studies
- Fungal Biology and Applications
- Advanced Nanomaterials in Catalysis
- Chemical Synthesis and Analysis
- Immune Response and Inflammation
- Pharmacological Effects of Natural Compounds
- Adipose Tissue and Metabolism
Northwestern Polytechnical University
2016-2025
Heilongjiang University
2025
First Affiliated Hospital of Xi'an Jiaotong University
2025
Beijing Tian Tan Hospital
2024
Capital Medical University
2024
Xiamen University
2022-2024
Hebei GEO University
2024
China XD Group (China)
2016-2021
Yichang Central People's Hospital
2021
University of California, Los Angeles
2016-2018
Selenium (Se) is an essential element for human and animal health. Biogenic selenium nanoparticles (SeNPs) by microorganism possess unique physical chemical properties biological activities compared with inorganic Se organic Se. The study was conducted to investigate the mainly of SeNPs Lactobacillus casei ATCC 393 (L. 393). results showed that L. transformed sodium selenite red size 50-80 nm, accumulated them intracellularly. 393-SeNPs promoted growth proliferation porcine intestinal...
Abstract Selenium (Se) is an essential micronutrient that promotes body health. Endemic Se deficiency a major nutritional challenge worldwide. The low toxicity, high bioavailability, and unique properties of biogenic nanoparticles (SeNPs) allow them to be used as therapeutic drug supplement. This study was conducted investigate the regulatory effects dietary SeNPs supplementation on oxidative stress-induced intestinal barrier dysfunction its association with mitochondrial function gut...
AIM:To investigate the protective effect of glutamine (Gln) on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment.METHODS: Sprague-Dawley were divided into control, (HH), + Gln (5.0 g/kg BW•d) (HG) groups.On first 3 d, all placed a normal environment.After third day, HH HG groups transferred chamber at simulated elevation 7000 m for 5 d.The group given by gavage daily 8 control treated with same volume saline.The morphology, serum levels...
Biogenic SeNPs synthesized by <italic>Lactobacillus casei</italic> ATCC 393 reversed diquat-induced oxidative damage to the epithelium activating Nrf2 signaling pathway.
Background: Selenium (Se) can exert antioxidative activity and prevent the body from experiencing oxidative injury. Biogenic Se nanoparticles (SeNPs) synthesized by probiotics possess relatively strong chemical stability, high bioavailability, low toxicity, this makes them potential supplements. Previously, we demonstrated that SeNPs Lactobacillus casei ATCC 393 alleviate hydrogen peroxide (H2O2)-induced human porcine intestinal epithelial cells' damage. However, antioxidant mechanism...
Purpose: The bidirectional communication between the gut and central nervous system mediated by microbiota is closely related to occurrence development of neurodegenerative diseases, including Alzheimer’s disease (AD). Selenium (Se) has been identified as playing a role against AD. Probiotics have beneficial effects on host brain function behavior modulating microbiota-gut-brain axis. Herein, we evaluated protective Lactobacillus casei ATCC 393 ( L. 393) selenium nanoparticles-enriched...
Lactococcus lactis (L. lactis) NZ9000, which has been genetically modified, is the most commonly used host strain for nisin regulated gene expression. Selenium (Se) an essential trace element in diet of humans and animals important maintenance health growth. Biosynthesized Se nanoparticles (SeNPs) that use microorganisms as a vehicle are uniquely advantages terms low costs, toxicity high bioavailability. This study was aimed at preparing novel functionalized SeNPs by L. NZ9000 through...
Inflammatory bowel disease (IBD) represents a broad group of intestinal disorders, including ulcerative colitis (UC) and Crohn's (CD). Probiotics are increasingly being recognized as means treatment for people suffering from IBD. Our previous studies demonstrated that Lactobacillus casei ATCC 393 (L. 393) effectively alleviated enterotoxigenic Escherichia coli K88-induced barrier dysfunction. This study was conducted to investigate the protective effects L. its metabolites on dextran sulfate...
Deoxynivalenol (DON), a secondary product of Fusarium metabolism, is common in wheat, corn, barley and other grain crops, posing variety adverse effects to environment, food safety, human animal health. The absorption DON mainly occurs the proximal part small intestine, which can induce intestinal mucosal epithelial injury, ultimately affect growth performance production animals. This study was conducted investigate protective selenium nanoparticles (SeNPs)-enriched Lactobacillus casei ATCC...
The immunomodulatory and antioxidant activities of crude polysaccharides extracted from Gynostemma pentaphyllum Makino (GPMPP) were investigated. GPMPP was composed rhamnose, arabinose, xylose, mannose, glucose galactose in the molar ratio 1.39:3.76:1.00:1.64:4.98:5.88. In vivo studies showed significantly increased spleen thymus indices, activated macrophage phagocytosis NK cells, exhibited activity on none or Con A/LPS-stimulated splenocytes a dose-dependent manner C57BL/6 mice. Moreover,...
Toll-like receptors (TLRs) recognize microbial pathogens and trigger immune response, but their regulation by neuropeptide-vasoactive intestinal peptide (VIP) in weaned piglets infected enterotoxigenic Escherichia coli (ETEC) K88 remains unexplored. Therefore, the study was conducted to investigate its role using a model of early ETEC K88. Male Duroc × Landrace Yorkshire (n = 24) were randomly divided into control, K88, VIP, K88+VIP groups. On first three days, groups orally administrated...
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) which related to immunological imbalance of the intestinal mucosa. Many clinical evidences indicate probiotics supplementation appears be effective and safe in patients with UC. Vasoactive peptide (VIP) endogenous neuropeptide multiple physiological pathological effects. In this study, we investigated protective effect combination Lactobacillus casei ATCC 393 (L. 393) VIP on dextran sodium sulfate (DSS)-induced UC mice potential...
Selenium nanoparticles (SeNPs) are proposed as a safer and more effective selenium delivery system than sodium selenite (Na2SeO3). Here, we investigated the effects of replacing dietary Na2SeO3 with SeNPs synthesized by Lactobacillus casei ATCC 393 on growth performance gut health early-weaned piglets. Seventy-two piglets (Duroc × Landrace Large Yorkshire) weaned at 21 d age were divided into control group (basal diet containing 0.3 mg Se/kg from Na2SeO3) SeNPs) during 14-d feeding period....