Outcomes of 1019 brachial plexus lesions in patients who underwent surgery at Louisiana State University Health Sciences Center during a 30-year period are reviewed this paper to provide management guidelines.Causes included 509 stretches/contusions (50%), 161 tumors (16%), 160 thoracic outlet syndromes (TOSs, 16%), 118 gunshot wounds (12%), and 71 lacerations (7%). Many features clinical presentation, including prior treatment, patient's neurological status, results electrophysiological...

Object The authors of previous in vitro investigations have reported an increase adjacent-level intradiscal pressures (IDPs) and facet joint stresses following cervical spine fusion. This study was performed to compare IDPs force arthroplasty with the fusion model. Methods Eighteen human cadaveric spines were tested intact state for different modes motion (extension, flexion, bending, rotation) up 2 Nm. specimens then divided into three groups: those involving ProDisc-C artificial disc,...

OBJECTIVE: This study analyzes 318 operative knee-level common peroneal nerve lesions managed at the Louisiana State University Health Sciences Center between 1967 and 1999. METHODS: Each patient was retrospectively evaluated for injury mechanism, preoperative neurological status, electrophysiological studies, lesion type, technique, i.e., neurolysis, suture, or graft repair. All in continuity had intraoperative action potential recordings. RESULTS: There were 141 stretch/contusions without...

Object. In this article the authors present a retrospective analysis of 654 surgical outcomes in patients with ulnar nerve entrapments, injuries, and tumors during 30-year period. Methods. Data were gathered between 1968 1998 at Louisiana State University Health Sciences Center. Mechanisms injuries or lesions included 460 entrapments elbow level (70%), 76 lacerations (12%), 52 stretches/contusions (8%), 34 fractures/dislocations (5%), 12 gunshot wounds (2%), two injection-induced (0.3%), 13...

This is a retrospective analysis of 353 surgically treated sciatic nerve lesions in which injury mechanisms, location, time to surgical repair, techniques, and functional outcomes are reported. Results presented provide guidelines for management these injuries.One hundred seventy-five patients with buttock-level 178 thigh-level were at the Louisiana State University Health Sciences Center between 1968 1999. Buttock-level mechanisms included injection 64 patients, hip fracture/dislocation 26,...

Abstract Maintaining DNA integrity is vital for all cells and organisms. Defective repair may contribute to neurological disorders, including Alzheimer’s disease (AD). We found reduced levels of BRCA1, but not other factors, in the brains AD patients human amyloid precursor protein (hAPP) transgenic mice. Amyloid-β oligomers BRCA1 primary neuronal cultures. In wild-type mice, knocking down dentate gyrus caused increased double-strand breaks, shrinkage, synaptic plasticity impairments,...

The facet joint has been identified as a significant source of morbidity in lower back pain. In general, treatments have focused on reducing the pain associated with osteoarthritis, and no targeted development replacement tissue for arthritic articular cartilage. Therefore, objective this study was to develop nonimmunogenic decellularized cartilage while maintaining functional properties similar native tissue.In vitro testing performed bovine explants. effects 2% sodium dodecyl sulfate...

Cyclophosphamide is increasingly used to treat various types of cancers and autoimmune conditions. Higher doses this drug may produce significant cardiac toxicity, including fatal hemorrhagic myocarditis. In review, we present a case cyclophosphamide-induced cardiomyopathy requiring mechanical circulatory support. We also describe the pathophysiology, clinical manifestations, risk factors for important entity propose early detection management strategies.

Exotic topology on the surface Analyzing spatial symmetries of three-dimensional (3D) crystal structures has led to discovery exotic types quasiparticles and topologically nontrivial materials. Wieder et al. focus symmetry groups 2D surfaces 3D materials—the so-called wallpaper groups—and find that some them allow for an additional topological class. This class hosts a single fourfold-degenerate Dirac fermion material and, basis authors' calculations, is expected occur in compound Sr 2 Pb 3...

Object. The authors present a retrospective analysis of 119 surgically treated femoral nerve lesions at intrapelvic and thigh levels seen the Louisiana State University Health Sciences Center. Methods. Femoral between 1967 2000, (89 traumatic injuries 30 tumors cystic lesions) were evaluated for injury mechanisms, resulting lesions, surgical management, postoperative functional outcomes by using chart reviews. most common mechanism was iatrogenic (52 cases), which occurred after hernia hip...

A retrospective analysis of clinical results in a relatively large series peroneal nerve lesion is presented. Historically, such lesions have been difficult to manage successfully.Between 1967 and 1991, 302 patients with either injury or tumor the at knee were evaluated Louisiana State University Medical Center. Mechanisms included stretch without fracture, "sharp" "blunt" laceration, gunshot wound, compression, entrapment, iatrogenic injury. Surgery was performed on 183 276 (66%). If...

Patients prefer minimally invasive techniques because such reduce recovery times and provide cosmetic benefits. Reviewing the history of surgery helps us understand advances in spine surgery. Minimally has adopted from several fields to better treat spinal disorders. been influenced by lasers, endoscopy, image guidance systems. Discogenic disorders have treated using chemonucleolysis, automated percutaneous discectomy, intradiscal thermoablation. Endoscopic used Thoracoscopes laparoscopes...

The concept of minimally invasive spinal surgery embodies the goal achieving clinical outcomes comparable to those conventional open surgery, while minimizing risk iatrogenic injury that may be incurred during exposure process. development microscopy, laser technology, endoscopy, and video image guidance systems provided foundation on which is based. Minimally treatments have been undertaken in all areas axis since 20th century. Lumbar disc disease has treated using chemonucleolysis,...

Patient reported mood charts are frequently used in management of bipolar disorder. Although have recently been programmed electronic devices such as mobile phones, little is known about the impact method data capture on psychometric properties and validity these data.

The goal of this paper was to review surgical management and outcomes in patients treated for radial nerve (RN) lesions at Louisiana State University Health Sciences over a period 30 years.Two hundred sixty with RN injuries were evaluated. most common mechanisms involving the included fracture humerus, laceration, blunt contusions, gunshot wounds. One eighty (69%) underwent surgery. Lesions not continuity required primary or secondary end-to-end suture repairs graft repairs. With use direct...

Object Range of motion (ROM) changes were evaluated at the surgically treated and adjacent segments in cadaveric specimens with two different cervical artificial discs compared those measured intact spine fusion models. Methods Eighteen human spines tested state for modes (extension, flexion, lateral bending, axial rotation) up to 2 Nm. Three groups (fitted either ProDisc-C or Prestige II disc submitted anterior discectomy [ACDF]) after implantation C6–7 level. The ROM values segments, these...

Twelve rabbits were used to study functional nerve regeneration through macropore, semipermeable, and nonpermeable collagen conduits. Each animal underwent a 10-mm bilateral resection of posterior tibial nerve. Lesions repaired with macropore tube in one leg, semipermeable or contralaterally. Functional was evaluated at 6 12 weeks post-repair periods. recovery assessed by electrophysiologic analysis conduction velocity, amplitude action potential, area muscle quantitative qualitative...

A biomechanical study.To evaluate the properties of a novel dynamic interspinous device named LockeThere has been no study on this device.Five human cadaveric lumbar spine specimens (L2-S1) were tested in following sequence: (1) intact state; (2) after removal ligaments L3-L4; (3) application Locker at space; (4) destabilization L3-L4 motion segments; and (5) reapplication to destabilized segments. Range (ROM) intradiscal pressure measured by video-based capture system needle...