A5082979652- Influenza Virus Research Studies
- Monoclonal and Polyclonal Antibodies Research
- Respiratory viral infections research
- Mass Spectrometry Techniques and Applications
- RNA and protein synthesis mechanisms
- Cancer-related gene regulation
- Chronic Lymphocytic Leukemia Research
- Appendicitis Diagnosis and Management
- Cancer Diagnosis and Treatment
- Isotope Analysis in Ecology
- Systemic Lupus Erythematosus Research
- Viral Infections and Immunology Research
- Minimally Invasive Surgical Techniques
- Uterine Myomas and Treatments
- Geology and Paleoclimatology Research
- Immune Cell Function and Interaction
- Toxin Mechanisms and Immunotoxins
- PI3K/AKT/mTOR signaling in cancer
- Immunodeficiency and Autoimmune Disorders
- Biosimilars and Bioanalytical Methods
VIR Biotechnology (United States)
2023-2025
Vir Biotechnology (Switzerland)
2025
Ames Research Center
2019
United States Food and Drug Administration
2014
Center for Drug Evaluation and Research
2012
Chinese University of Hong Kong
2001-2004
Prince of Wales Hospital
2004
Rapidly evolving influenza A viruses (IAVs) and B (IBVs) are major causes of recurrent lower respiratory tract infections. Current vaccines elicit antibodies predominantly to the highly variable head region haemagglutinin their effectiveness is limited by viral drift1 suboptimal immune responses2. Here we describe a neuraminidase-targeting monoclonal antibody, FNI9, that potently inhibits enzymatic activity all group 1 2 IAVs, as well Victoria/2/87-like, Yamagata/16/88-like ancestral IBVs....
Respiratory viruses represent a major global health burden. Although these have different life cycles, they may depend on common host genetic factors, which could be targeted by broad-spectrum host-directed therapies. We used genome-wide CRISPR screens and advanced data analytics to map network of genes that support infection nine human respiratory [influenza A virus, parainfluenza rhinovirus, syncytial coronavirus (HCoV)-229E, HCoV-NL63, HCoV-OC43, Middle East syndrome–related coronavirus,...
To compare postoperative wound pain associated with the radially expanding access device and conventional disposable cutting-tip trocar.Our randomized, double-masked, self-controlled study involved 34 women scheduled for laparoscopic adnexal surgery. In each, a 10-mm was inserted laterally on one side of lower abdomen size-matched trocar placed other side, using random assignment. Postoperative each studied patient satisfaction toward wounds were assessed visual analog scale. Any bleeding...
In the aftermath of COVID-19 pandemic, opportunities to modulate biological pathways common lifecycles viruses need be carefully considered.