A5111704919- RNA modifications and cancer
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- Ferroptosis and cancer prognosis
- Acute Kidney Injury Research
- Cancer Immunotherapy and Biomarkers
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- PI3K/AKT/mTOR signaling in cancer
- Epigenetics and DNA Methylation
- Cancer Genomics and Diagnostics
- Pregnancy and Medication Impact
- Cancer Cells and Metastasis
- Metabolism, Diabetes, and Cancer
- Cell Adhesion Molecules Research
- HER2/EGFR in Cancer Research
- S100 Proteins and Annexins
- Immunotherapy and Immune Responses
- Bioinformatics and Genomic Networks
- Radiopharmaceutical Chemistry and Applications
- Trace Elements in Health
- Cancer-related Molecular Pathways
- Acute Myeloid Leukemia Research
- Advanced Breast Cancer Therapies
- Hematopoietic Stem Cell Transplantation
- Immune cells in cancer
First Affiliated Hospital of GuangXi Medical University
2022-2025
Central South University
2024-2025
Guangxi Medical University
2022-2025
National Pingtung University of Science and Technology
2025
Jiangsu Provincial Center for Disease Control and Prevention
2022-2024
Zhejiang A & F University
2024
Zhejiang Sci-Tech University
2024
Zhejiang University
2024
Shangrao Normal University
2022-2024
Zhuzhou Central Hospital
2020-2024
This study employed sero-epidemiological methods to estimate the incidence of pertussis within a healthy population located in eastern China. The aim was gain deeper insights into epidemiological characteristics and burden country. Blood samples were collected from individuals Jiangsu Province between June 2019 December 2022. levels IgG antibodies against toxin (anti-PT) filamentous hemagglutinin (anti-FHA) serum quantitatively measured using enzyme-linked immunosorbent assay (ELISA)....
Background: S-ketamine (the S-isomer of ketamine) is twice as potent the racemic mixture this agent and carries fewer side effects when administered to humans. Information regarding use for prevention emergence delirium (ED) limited. Thus, we evaluated effect at end anesthesia on ED in preschool children undergoing tonsillectomy and/or adenoidectomy. Methods: We investigated 108 aged 3–7 years, who were scheduled elective adenoidectomy under general anesthesia. They randomly assigned receive...
We perform Bayesian joint inversion on controlled-source audio-frequency magnetotelluric (CSAMT) and direct current (DC) resistivity data using geostatistical modeling to incorporate prior constraints physical properties. This study focuses the Jinba gold deposit in Xinjiang, China, demonstrating effectiveness of integrating CSAMT DC enhanced subsurface imaging. By leveraging knowledge employing Markov chain Monte Carlo (MCMC) sampling, we quantify uncertainty results compare improvements...
This study investigated common diagnoses from surgical biopsies of domestic rabbits (Oryctolagus cuniculi) in Taiwan and examined the role leporipoxvirus tumor pathogenesis. Biopsy specimens 70 collected between 2014 2023 were retrospectively analyzed, yielding 85 diagnoses. Polymerase chain reaction (PCR) was performed to detect formalin-fixed, paraffin-embedded tissues diagnosed with fibroma, fibrosarcoma, or myxosarcoma. The most commonly affected systems integumentary (n = 41)...
The impact of obesity on the severity acute pancreatitis and subsequent gastrointestinal injury remains an important consideration. This study aimed to determine clinical relationship between in earlystage pancreatitis.This was a prospective that enrolled 194 patients.The median body mass index 26.5 (7.0) kg/m2. Considering etiology pancreatitis, 90 patients had gallstones, 48 hypertriglyceridemia, 36 were alcohol users, 20 others. A total 116 mild rest severe pancreatitis. bedside score 1...
We report radio-frequency (RF) MOSFETs with a two-dimensional-electron-gas-like (2DEG-like) channel formed at the <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula> -Ga <sub xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> surface through low-energy implantation of Si and rapid thermal activation process. The shallowly...
Introduction The dramatic decrease in the number of reported cases pertussis during COVID-19 pandemic has been underestimated. objective was to compare estimated incidence rate populations pre- and post-COVID-19 by analyzing anti-pertussis toxin (anti-PT) IgG anti-filamentous hemagglutininant (anti-FHA) antibodies healthy Chinese population from 2018 2021. Methods All serum samples ( N = 1,000) were collected (aged ≥ 15 years) who attended an annual monitoring project antibody levels Jiangsu...
Acute myeloid leukemia, constituting a majority of leukemias, grapples with 24% 5-year survival rate. Recent strides in research have unveiled fresh targets for drug therapies. LIM-only, pivotal transcription factor within LIM proteins, oversees cell development and is implicated tumor formation. Among these critical CSRP1, Cysteine-rich protein, emerges as significant player various diseases. Despite its recognition potential prognostic therapeutic target cancers, the specific link between...
Current knowledge about clinical and genetic risk factors for aspirin-induced gastric mucosal injury is not sufficient to prevent these lesions.We recruited aspirin takers as the exposed group healthy volunteers control group. The was categorized into two subgroups such subgroup A diagnosed by gastroscopy, including erosion, ulcer or bleeding of esophagus, stomach, duodenum; B no mucosa detected gastroscopy. Clinical information collected, 53 single nucleotide polymorphisms were...
Background: Thalidomide is effective in inducing and maintaining clinical remission children adolescents with refractory Crohn’s disease (CD). However, little known about the efficacy safety of thalidomide for adult patients CD. Methods: We conducted a prospective open-label cohort study between January 2013 April 2015. A total 47 active CD who were dependent/resistant or intolerant to corticosteroids and/or immunomodulators biologics received 50–100 mg daily. Primary outcome was evaluated...
Objectives: Many studies on the relationship between gastroesophageal reflux disease (GERD) and laryngopharyngeal (LPR) were based symptoms, but there are few research it using monitoring. This study was designed to investigate GERD LPR pH Methods: All patients scheduled for esophageal manometry monitoring sequentially. They stratified into 4 groups as no disease, isolated GERD, (iLPR), combined with (GERD&LPR) according Results: The incidence of in 46.3%, while probability combining...
Objective: To investigate the factors influencing pharmacokinetics of mycophenolate mofetil (MMF) in pediatric patients after liver transplantation, and to establish a population model, which can provide reference for clinical dosage adjustment. Methods: A prospective study single center was performed on who were administrated with dispersible tablets (MMFdt) at least 4 days transplantation continuously. Blood samples collected ethylene diamine tetraacetic acid anticoagulant tubes before...
Ascl2 has been shown to be involved in tumorigenesis colorectal cancer (CRC), although its epigenetic regulatory mechanism is largely unknown. Here, we found that methylation of the promoter (bp -1670 ∼ -1139) was significantly increased compared other regions locus CRC cells and associated with elevated mRNA expression. Furthermore, predictive patient survival after analyzing DNA data, RNA-Seq clinical data 410 samples from MethHC database, MEXPRESS Cbioportal website. Using established TET...
Like other cancers, considerable effort has been made in acute myeloid leukemia (AML) to identify prognostic genes and long noncoding RNAs (lncRNAs) with their potential clinical applications. However, date, no integrated model developed that combines both gene expression lncRNAs as a singular approach AML.Comprehensive bioinformatic approaches (Weighted co-expression network analysis, Univariate Cox regression analyses, Pearson correlation, LASSO-Cox regression, Wilcoxon test) were used...
Objective This study investigates the effectiveness of tibia periosteum distraction (TPD) applied to tibial periosteum, an innovative approach grounded in Ilizarov’s tension-stress theory, for treatment ischemic diabetic foot and vasculitic conditions. Methods A retrospective analysis was conducted on 33 patients (36 limbs) who underwent TPD between June 2019 May 2022. The comprised 21 males (23 12 females (13 limbs), aged 41 80 years (mean age: 63.4 years). Diabetic accounted 27 cases,...
A diagnostic dilemma can be encountered when primary triple-negative breast carcinoma (TNBC) without an in-situ component or metastatic TNBCs lose the currently used organ-specific marker such as GATA3, raising concerns about from other sites. In current study, we compared newly identified TRPS1 with markers GATA3 and SOX10 in whole-tissue sections 315 cases of various subtypes TNBC. was highly expressed 100% invasive lobular carcinomas, 99% no special type (IBC-NST) 95% metaplastic...
The role of MMP-2 in patients with ICH is controversial and the impact plasma level on clinical outcome still unclear. In this study, peripheral venous blood was acquired from 93 88 healthy controls within 24 h hospitalization at enrollment. We retrospectively investigated levels controls. edema volume, NIHSS score, GCS mRS were used to assess quantify neurological deficit following ICH. Logistic regression analysis configured determine independent relation outcomes. addition, MMP-14...
Understanding the spatiotemporal patterns of animal movement is a central theme in growing field ecology. The Bridled Tern (Onychoprion anaethetus) widely distributed across tropical and subtropical latitudes; however, knowledge its annual based only on relatively scarce recoveries ringed birds. Studying pelagic seabirds important to identify impact changes marine habitats them. We examined fine-scaled species from two colonies southern China by using GPS-GSM transmitters 2018–2022....
Cone snails, which are predatory marine gastropods, produce a cocktail of venoms used for predation, defense and competition.The major venom component, conotoxin, has received significant attention because it is useful in neuroscience research, drug development molecular diversity studies.In this study, we report the genomic characterization nine conotoxin gene superfamilies from 18 Conus species investigate relationships among structure, evolution diversity.The I1, I2, M, O2, O3, P, S, T...
Fundoplication as well silicone antireflux prosthesis are procedures of known efficacy. Both accompanied in 10–15% the cases by cuff and complications. We investigated whether fundoplication create an unphysiological barrier, which may explain described postoperative symptoms. The results pH-metry show that a significant reduction 24 h reflux be achieved both operations. In this regard, particular importance attributed to almost complete suppression postprandial gastroesophageal from 7.7 ±...
With the rapid development of anesthesiology, anesthesiologists have accumulated rich clinical experience in rescuing critically ill patients.Anesthesia intensive care unit (AICU) is a specific hospital area that managed and organized by anesthesiology critical service.AICU offers multidisciplinary for patients perioperative period through team specialists, predominantly anesthesiologists.By end 2022, surge Coronavirus Disease 2019 (COVID-19) cases has overwhelmed healthcare services our...
The purpose of this study was to investigate possible influencing factors based on the distribution pertussis toxin (PT) and filamentous hemagglutinin (FHA) antibody levels in 0-14-year-old children Jiangsu Province, China, analyze changes IgG after vaccination over time via a restricted cubic spline (RCS)-fitted binary logistic regression model. We collected surveillance data through National Notifiable Disease Reporting System (NNDRS). Serum samples were collected, PT IgG/FHA determined an...
MicroRNA156 (miR156), targeting a subset of <italic>SQUAMOSA PROMOTOR BINDING PROTEIN-LIKE</italic> (<italic>SPL</italic>) genes, is one the most evolutionarily conserved microRNAs (miRNAs) in plants. miR156 recognized molecular marker plant age. In addition to being an age indicator, has demonstrated strong multifunctionality regulation broad range biological processes horticultural plants, including vegetative growth, floral induction, fruit ripening, stress responses, and secondary...