A5005111872- Analytical Chemistry and Chromatography
- Advanced Photocatalysis Techniques
- Mass Spectrometry Techniques and Applications
- TiO2 Photocatalysis and Solar Cells
- Conducting polymers and applications
- Higher Education and Teaching Methods
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Organic Electronics and Photovoltaics
- Wastewater Treatment and Nitrogen Removal
- Metabolomics and Mass Spectrometry Studies
- Advanced biosensing and bioanalysis techniques
- Advanced Decision-Making Techniques
- Pharmaceutical and Antibiotic Environmental Impacts
- Pesticide and Herbicide Environmental Studies
- Quantum Dots Synthesis And Properties
- Education and Work Dynamics
- Synthetic Organic Chemistry Methods
- Natural product bioactivities and synthesis
- Cyclopropane Reaction Mechanisms
- Catalytic C–H Functionalization Methods
- Microbial bioremediation and biosurfactants
- Constructed Wetlands for Wastewater Treatment
- Organic Light-Emitting Diodes Research
- Biosensors and Analytical Detection
Beijing Radiation Center
2015-2024
Beijing Normal University
2020-2024
Xi’an International University
2019-2023
Uppsala University
2023
Universiti of Malaysia Sabah
2019-2022
Yunnan Agricultural University
2022
Universiti Sains Islam Malaysia
2022
Zhengzhou University
2018-2020
Jianghan University
2015-2019
AstraZeneca (United States)
2014-2017
The present study investigated the feasibility of using a photo-Fenton oxidation process for degradation ciprofloxacin hydrochloride. pH value solutions, dosages hydrogen peroxide and ferrous ion, reaction temperature, presence chloride which affect hydrochloride wastewater, were studied based on changes concentration UV-absorbance wastewater. Results indicated that could be degraded effectively by in wide range 3.0 to 5.0; optimum ion selected as 5.0 0.05 mmol L−1, respectively; increase...
BackgroundHepatocellular carcinoma (HCC) is prevalent worldwide and early diagnosis of HCC critical for effective treatment optimal prognosis.MethodsSerum was screened first by immunoproteomic analysis HCC-related tumor associated antigens (TAAs). Selected TAAs were clinically evaluated retrospectively in patients with HCC, liver cirrhosis, chronic hepatitis healthy controls. Levels autoantibody to the selected measured protein microarrays containing candidate TAAs. Analyses done using...
The stereoselective sequential spirocyclopropanation/Cloke–Wilson rearrangement reactions have been developed to synthesize γ-butyrolactones using alkylidene Meldrum's acids and benzyl halides. DBU-promoted spirocyclopropanation was carried out efficiently at room temperature generate trans-isomeric spirocyclopropyl acid, the following stereospecific thermal decarboxylative Cloke–Wilson afforded trans-γ-butyrolactones. A variety of aromatic aliphatic acid derived olefins halides were...
The in vivo oxidation of sulfur and nitrogen atoms many drugs into sulfoxide N-oxide functionalities is a common biotransformation process. Unfortunately, the unambiguous identification these metabolites can be challenging. In present study, ion–molecule reactions tris(dimethylamino)borane followed by collisionally activated dissociation (CAD) an ion trap mass spectrometer are demonstrated to allow protonated polyfunctional drug metabolites. Only ions with or functionality formed diagnostic...
Base-mediated stereospecific tandem reactions using para-quinone methides and carbene-like benzyl chlorides are developed. DBU-mediated 1,6-addition/cyclization/isomerization produce triarylsubstituted alkenes in 43–89% yields Z/E ratios of 5:1 to 35:1 favor the Z-isomers. Single-step 1,6-conjugate additions realized with mediation cesium carbonate, different triaryl chloroethanes obtained 41–54% excellent diastereoselectivities more than 20:1. In addition, 1,6-addition/cyclization achieved...
Abstract The use of next generation sequencing is increasing in the field forensic genomics. This study assesses performance Illumina's MiSeq FGx System recovery genomic information from degraded and low‐template DNA. analysis involved a sensitivity where range 1 ng to 5 pg 2800M DNA was utilized. artificially systematically by incubating 2800 M at 98°C for 10, 20, 30, 40, 50, 60, 70, 120 180 min (resulting degradation index values ranging 0.837 232.247). results revealed detected allele...
The organobase-mediated diastereoselective spirocyclopropanation of barbiturate-based olefins with 2,4-disubstituted benzyl chlorides has been developed. reactions were carried out efficiently to afford the desired spirobarbiturate-cyclopropanes in up 95% yield more than 20:1 dr favor anti-isomers. In order extend synthetic utility spiro-products, a Lewis acid induced cyclopropane-ring-expansion isomerization was also demonstrated.
Symmetry-breaking charge separation in molecular materials has attracted increasing attention for optoelectronics based on single-material active layers. To this end, Fe(III) complexes with particularly electron-donating N-heterocyclic carbene ligands offer interesting properties a 2LMCT excited state capable of oxidizing or reducing the complex its ground state. In Communication, we show that corresponding symmetry-breaking occurs amorphous films pristine [Fe(III)L2]PF6 (L =...
A tandem mass spectrometric method is presented for the rapid identification of drug metabolites that contain sulfone functional group. This based on a gas-phase ion/molecule reaction protonated analytes with trimethyl borate (TMB) yields diagnostic product ion, adduct-Me2O, at high efficiency. variety compounds different groups, such as sulfoxides, hydroxylamines, N-oxides, anilines, phenol, an aliphatic amine, and alcohol, were examined to probe selectivity this reaction. Except sulfones,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNagilactones from Podocarpus nagi and Their Effects on the Feeding Growth of Tobacco BudwormMinli Zhang, Bai-ping Ying, Isao KuboCite this: J. Nat. Prod. 1992, 55, 8, 1057–1062Publication Date (Print):August 1, 1992Publication History Published online1 July 2004Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/np50086a004https://doi.org/10.1021/np50086a004research-articleACS PublicationsRequest reuse permissionsArticle...
The BP model in artificial neural network is used this paper. Various factors that affect the tender offer identified and these as input nodes of to conduct iterated operation applied Through taking advantage self-learning function network, paper constantly modifies weight matrix achieve objective error predicting offer. As a software support tool, MATLAB toolbox helps reduce workload writing code greatly make application more widely.
Gas-phase reactivity of protonated model compounds with different functional groups toward trimethoxymethylsilane (TMMS) was studied to explore the utility this reagent in mass spectrometric identification specific functionalities for potentially rapid characterization drug metabolites. Only analytes a carboxylic acid, sulfone, or sulfonamide functionality formed diagnostic adducts that had lost methanol molecule upon reactions TMMS. Collisionally activated dissociation (CAD) these...
Charge recombination in high-efficiency non-fullerene cells (PCE = 9.25%) is much more serious than that of fullerene based 6.95%).
A mass spectrometric method utilizing gas-phase ion/molecule reactions of 2-methoxypropene (MOP) has been developed for the identification sulfoxide functionality in protonated analytes a LQIT spectrometer.
Rationale N ‐Monosubstituted hydroxylamines correspond to an important class of metabolites for many bioactive molecules. In this study, a tandem mass spectrometric method based on ion/molecule reactions was developed the identification compounds with ‐monosubstituted hydroxylamino functionality. Methods The diagnostic reaction occurs between protonated analytes 2‐methoxypropene (MOP) inside linear quadrupole ion trap spectrometer. Results Most and disubstituted oxime functional groups react...