Chang Dong Han

ORCID: 0009-0007-9758-1970
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Orthopedic Infections and Treatments
  • Osteoarthritis Treatment and Mechanisms
  • Hip and Femur Fractures
  • Bone fractures and treatments
  • Bone Tissue Engineering Materials
  • Healthcare and Venom Research
  • Microbial Community Ecology and Physiology
  • Knee injuries and reconstruction techniques
  • Hip disorders and treatments
  • Bone and Joint Diseases
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Orthopedic Surgery and Rehabilitation
  • Sarcoma Diagnosis and Treatment
  • Membrane Separation and Gas Transport
  • Antibiotic Resistance in Bacteria
  • Gout, Hyperuricemia, Uric Acid
  • Phytoplasmas and Hemiptera pathogens
  • Ethics in Clinical Research
  • Diabetic Foot Ulcer Assessment and Management
  • Elbow and Forearm Trauma Treatment
  • Bone Tumor Diagnosis and Treatments
  • Bone and Dental Protein Studies
  • Blood transfusion and management

Xi'an Jiaotong University
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Hohai University
2024

Pennsylvania State University
2024

Institute of Entomology
2024

Changjiang Water Resources Commission
2024

Jiangsu University
2021-2022

Dalian Maritime University
2022

Research Center for Eco-Environmental Sciences
2020-2021

Chinese Academy of Sciences
2002-2021

The discovery of complete ammonia oxidation (comammox) has altered our understanding nitrification, which is the rate-limiting process in global nitrogen cycle. However, ecological role comammox or its contribution to nitrification both natural and artificial ecosystems still infancy. Here, we investigated community distribution function bacteria riparian analyzed interactions between other cycling microorganisms. bacterial abundance rate were higher summer than winter nonrhizosphere soils...

10.1021/acs.est.0c00915 article EN Environmental Science & Technology 2021-03-18

Abstract Background This study was designed to investigate the correlations of knee osteoarthritis (OA) with metabolic syndrome (MetS) and MetS parameters in Korean subjects. Methods included data from 270 subjects OA 1964 control a mean age 54.56 (SD 11.53) years taken National Health Nutritional Examination Survey (KNHANES) 2008. Multivariate logistic regression analysis conducted examine possible associations for parameters. Results shown be associated an increased risk female unadjusted...

10.1186/1471-2458-13-603 article EN cc-by BMC Public Health 2013-06-22

S-Adenosyl-l-methionine:phosphoethanolamine N-methyltransferase (PEAMT; EC 2.1.1.103) catalyzes the key step in choline (Cho) biosynthesis, N-methylation of phosphoethanolamine. Cho is a vital precursor membrane phospholipid phosphatidylcholine, which accounts for 40 to 60% lipids nonplastid plant membranes. Certain plants use produce osmoprotectant glycine betaine, confers resistance salinity, drought, and other stresses. An Arabidopsis mutant, t365, PEAMT gene silenced, was identified...

10.1105/tpc.001701 article EN The Plant Cell 2002-08-23

To compare the clinical outcome and complications following total knee arthroplasty (TKA) in diabetic non-diabetic patients, to identify diabetes-related risk factors for negative outcomes.222 primary TKAs patients with diabetes were evaluated using Knee Society scores Hospital Special Surgery score. Postoperative reviewed retrospectively. The mean follow-up was 53.2 months. effect of comparison a matched control group analyzed statistically.Significant improvements noted all after TKA (p <...

10.3349/ymj.2008.49.1.129 article EN cc-by-nc Yonsei Medical Journal 2008-01-01

Cyclooxygenase-2 (COX-2) inhibitors suppress bone repair and formation by suppressing angiogenesis as well potentially interfering with osteoblast osteoclast functions. In spite of these reports, there is a controversy over the exact effects COX-2 on processes itself. This work was designed to investigate effect inhibitor osteogenesis human marrow-derived mesenchymal stem cells (MSC). MSCs in were treated (celecoxib naproxen) absence or presence interleukin-1β (IL-1β), which used induce...

10.1089/scd.2009.0393 article EN Stem Cells and Development 2010-01-22

Background The aim of this study was to compare the clinical and radiologic outcomes robot-assisted unicompartmental knee arthroplasty (UKA) those conventional UKA in Asian patients. Methods Fifty-five patients underwent 57 were assessed study. Preoperative postoperative range motion (ROM), American Knee Society (AKS) score, Western Ontario McMaster University Osteoarthritis Index scale score (WOMAC), patellofemoral (PF) values compared between two groups. mechanical femorotibial angle...

10.1371/journal.pone.0225941 article EN cc-by PLoS ONE 2019-12-03

Antibiotic-loaded bone cement (ALBC) has been used in serious cases of musculoskeletal tuberculosis, but the type and amount antibiotic that should be ALBC have not determined.We therefore determined (1) elution characteristics (2) antimycobacterial activity isoniazid- rifampicin-loaded cement.A total 240 samples each three discs from 40 g mixed with one eight dosages: 1 g, 2 4 isoniazid, rifampicin, a combination + or isoniazid rifampicin. The polymerization was delayed to mean 122.5 ± 31.1...

10.1007/s11999-013-2899-5 article EN Clinical Orthopaedics and Related Research 2013-03-16

Aluminium (Al3+) inhibits root growth of sensitive plant species and is a key factor that limits durum wheat (Triticum turgidum) production on acid soils. The aim this study was to enhance the Al3+ tolerance an elite cultivar by introgression chromosomal fragment from hexaploid aestivum) possesses gene. A 4D(4B) substitution line 'Langdon' backcrossed 'Jandaroi', current semi-dwarf Australian durum. In second backcross, using 'Jandaroi' as recurrent parent, seedling identified where TaALMT1...

10.1093/aob/mcu070 article EN Annals of Botany 2014-04-15

This comprehensive study examined the effects of two infrared drying modes: intermediate-wave (IWD) and catalytic (CID), on kinetics various quality parameters pineapple rings at 60–80 °C. Hot-air (HAD) was control operation. CID showed highest rates coefficients moisture diffusivity (3.05 × 10−8 m2/s to 5.12 m2/s), resulting in times (1.88–3.15 h) that were about half HAD (3.57–7.25 10–34% less than IWD (2.08–4.75 h). Compared IWD, exhibited minor color changes a stronger flavor profile...

10.1080/07373937.2022.2078834 article EN Drying Technology 2022-05-28

The selective adsorption of target acid gas molecules from binary mixtures by porous aromatic frameworks (PAFs) with two identical functional groups per ring (PAF-R2) was computationally investigated using grand canonical Monte Carlo simulations. PAF-R2 considered for three small molecular concentrations and abundant nitrogen (CO2/N2, SO2/N2, H2S/N2). results indicate that additional enhance loadings selectivity, compared pristine PAF single-functionalized PAFs. Low pressures yield linearly...

10.1021/acs.langmuir.3c03169 article EN Langmuir 2024-03-08

Three new species of the leafhopper genus Arboridia Zachvatkin 1946, (Arboridia) furcata Han, sp. nov. , rubrovittata and robustipenis are described illustrated from fruit trees in Southwest China. A key checklist to known China provided.

10.3897/zookeys.1196.118829 article EN cc-by ZooKeys 2024-03-28

Antibiotic-loaded bone cement is accepted as an effective treatment modality for musculoskeletal tuberculosis. However, comparative information regarding combinations and concentrations of second-line antimycobacterial drugs, such streptomycin amoxicillin clavulanic acid, are lacking.(1) In antibiotic-loaded cement, there elution Augmentin® (amoxicillin acid) individually in combination? (2) What the antibacterial activity duration streptomycin- acid -loaded cement?Six different types discs...

10.1007/s11999-017-5470-y article EN Clinical Orthopaedics and Related Research 2017-08-09

Abstract: Cellular toxicity, cell adhesion and proliferation, alkaline phosphatase (ALP) activity were investigated for an artificial bone substitute composed of heated carbonate apatite (CAp) Type I atelocollagen (AtCol) extracted from bovine tail skins (88/12 in %wt/wt). To enhance the intramolecular crosslinking between collagen molecules, CAp‐AtCol substitutes irradiated by ultraviolet rays (wave length 254 nm) at 4°C 4 h or vacuum dried 150°C 2 h. Cytotoxicity tests a direct contact...

10.1046/j.1525-1594.2001.025001014.x article EN Artificial Organs 2001-01-01

Abstract: Bone inducing agent (BIA) isolated from Saos‐2 human osteosarcoma cells was added to an artificial bone substitute composed of 980°C‐heated carbonate apatite (CAp) and Type I atelocollagen (AtCol) extracted bovine tail skins (88/12 in wt/wt %), a CAp‐AtCol‐BIA prepared as osteoinductive substitute. Rat calvaria osteoblasts treated by the BIA demonstrated significantly increased alkaline phosphatase (ALP) activity after 3 days (p &lt; 0.05). In vitro cell attachment proliferation...

10.1046/j.1525-1594.2001.025006459.x article EN Artificial Organs 2001-06-01

The defects of the articular cartilage structure are not replaced unless subchondral plate has been breached. However, following creation a defect in plate, area is filled with fibrous tissue which gradually transforms to hyaline cartilage. porous nontoxic materials both biologic and synthetic origin have reportedly used as matrices for repairing bone Following implantation, carbon fibre, chemically inert well-tolerated by body, induces proliferation ordered tissue. We implanted fiber pads...

10.3349/ymj.1991.32.2.108 article EN Yonsei Medical Journal 1991-01-01

The changes in the surface of articular cartilage femoral condyle from rabbits were evaluated after degenerative made by technique advocated Hulth. medial collateral and both cruciate ligaments excised, a menisectomy was done. Then right knee joint injected with 1 ml Na-hyaluronate gel every two weeks. animals sacrificed at two, four, six, eight, or sixteen weeks postoperatively. After sacrifice, excised prepared for light microscopic scanning electron study. At eight to weeks, there...

10.3349/ymj.1991.32.2.139 article EN Yonsei Medical Journal 1991-01-01
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