A5081139712- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Diet and metabolism studies
- Obstructive Sleep Apnea Research
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Gut microbiota and health
- Cardiovascular and Diving-Related Complications
- Sodium Intake and Health
- Diet, Metabolism, and Disease
- Neuroscience of respiration and sleep
- Body Composition Measurement Techniques
- Nutritional Studies and Diet
- Cardiovascular Disease and Adiposity
- Healthcare Systems and Public Health
Queen Giovanna Hospital
2019-2024
Medical University of Sofia
2024
Abstract Background: Trimethylamine N-oxide (TMAO) is synthesized by the intestinal microbiota and an independent predictor of cardiovascular disease (CVD). However, its underlying mechanisms remain unclear. We investigated TMAO levels across different CVD-risk patient groups, evaluated associations between vascular alterations (e.g., arterial stiffness, intima-media thickness [IMT], presence grade carotid artery plaques [CAPs]). Methods: examined 95 patients (58.5 ± 7.3 years): 40 with...
Background: Acute decompensated heart failure (ADHF) is a condition with high frequency of hospitalizations and mortality, obstructive sleep apnea (OSA) common comorbidity. Continuous positive airway pressure (CPAP) therapy at home can be good adjunctive non-drug for these patients. Methods: We conducted single-center, prospective cohort study from 150 consecutive patients hospitalized exacerbation in the cardiology department. Of these, 57 had apnea. After discharge, CPAP was offered....
Trimethylamine-N-oxide (TMAO) is a metabolite produced by intestinal microbiota. It well recognized as an independent risk marker for cardiovascular and renal diseases mortality.
Abstract Funding Acknowledgements Type of funding sources: None. BACKGROUND Arterial hypertension (HTN) is the most prevalent risk factor for Atrial fibrillation (AF) through structural and functional changes left atrium. Paroxysmal AF mainly asymptomatic silent forms in patients with HTN are associated thromboembolic complications. However, prompt identification at may be strategic preventing purposes. PURPOSE To assess sensitive predictive parameters onset using two-dimensional (2D)...
Abstract Background Exacerbated heart failure is a condition with high frequency of hospitalizations and mortality, especially in overweight patients. Screening treatment for sleep apnea can be helpful these Purpose To determine the phenotypic characteristics patients exacerbated failure. assess systolic diastolic function obstructive central apnea. follow one year to hospitalization mortality. Methods We conducted single-centre, prospective cohort study form 120 consecutive hospitalized...
Objective: Arterial hypertension is the most common contributor of cardiac remodeling, but this changes are observed in more advanced stages and uncontrolled hypertension. However little known about left heart geometry function well – controlled The aim study to investigate subclinical abnormalities middle aged patients with Design method: We studied 45 consecutive mild moderate duration up 5 years 15 healthy controls. All parameters for arterial stiffness 24 - hour central systolic pressure...
Background: Telemedicine is an alternative to the standard consultation with a specialist during COVID-19 pandemic. Though their benefits are not well studied, phone consultations potential effective resource for providing medical and psycho-social help patients chronic diseases social isolation. Aim: To assess demographic clinical characteristics of patients, who looked cardiology on phone, most common reasons these consultations. Material Methods: We analyzed data 196 consecutive...
Increased arterial stiffness is an early predictor of cardiovascular changes. However the association between with LV myocardial changes poorly understoodThe aim this study was to examine relationship and function in well - controlled hypertensive patients.Methods: A total 100 consecutive patients hypertension adapted by age, gender BMI, were separated two groups: 27 normal ventriculo coupling (VAC) 63 disturbed VAC, measured elastance/ventricular elastance ratio(AE/Ees). All underwent...
Abstract Objective: Arterial stiffness is an independent risk factor in arterial hypertension, but little known about the association between left atrial remodeling and middle – aged hypertensive patients. AIM: To investigate early changes (LA) mechanical function parameters of a population asymptomatic individuals. Design method: A total 95 patients (57 ± 14 years) with were separated two groups: 22 normal EA/Ees ratio (Arterial elastance (AE) ventricular (Ees))and 73 decrease ratio, marker...