Dan Xu

ORCID: 0009-0009-0833-9619
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About
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Research Areas
  • Adipose Tissue and Metabolism
  • Genetic and phenotypic traits in livestock
  • Glaucoma and retinal disorders
  • Lipid metabolism and biosynthesis
  • Genetic Mapping and Diversity in Plants and Animals
  • Cancer-related molecular mechanisms research
  • Plant and Fungal Interactions Research
  • Ophthalmology and Eye Disorders
  • Cerebral Venous Sinus Thrombosis
  • Ergonomics and Musculoskeletal Disorders
  • Plant tissue culture and regeneration
  • RNA Research and Splicing
  • Peroxisome Proliferator-Activated Receptors
  • Plant Pathogenic Bacteria Studies
  • Myxozoan Parasites in Aquatic Species
  • Natural Language Processing Techniques
  • Plant Disease Resistance and Genetics
  • Reproductive Physiology in Livestock
  • Protist diversity and phylogeny
  • Molecular Biology Techniques and Applications
  • Linguistics and Cultural Studies
  • Quinazolinone synthesis and applications
  • Musculoskeletal pain and rehabilitation
  • RNA modifications and cancer
  • Healthcare and Venom Research

University of Minnesota
2025

Hormel (United States)
2025

Wenzhou Medical University
2004-2023

Institut National des Langues et Civilisations Orientales
2021

Centre de Recherches Linguistiques sur l'Asie Orientale
2021

Yangtze Normal University
2020

Duke-NUS Medical School
2015-2018

Nanjing Agricultural University
2006-2018

Affiliated Eye Hospital of Wenzhou Medical College
2012-2015

Wenzhou University
2015

Obesity has emerged as an alarming health crisis due to its association with metabolic risk factors such diabetes, dyslipidemia, and hypertension. Recent work demonstrated the multifaceted roles of lncRNAs in regulating mouse adipose development, but their implication human adipocytes remains largely unknown. Here we present a catalog 3149 active lncRNAs, which 909 are specifically detected brown tissue (BAT) by performing deep RNA-seq on adult subcutaneous, omental white fetal BATs. A total...

10.1038/s41467-018-03754-3 article EN cc-by Nature Communications 2018-03-29

Fasciclin‐like arabinogalactan proteins (FLAs), a subclass of (AGPs), are usually involved in cell development plants. To investigate the expression profiling as well role FLA genes fiber development, 19 GhFLA (cDNAs) were isolated from cotton ( Gossypium hirsutum ). Among them, 15 predicted to be glycosylphosphatidylinositol anchored plasma membranes. The FLAs could divided into four groups. Real‐time quantitative reverse transcriptase polymerase chain reaction results indicated that...

10.1111/j.1399-3054.2008.01139.x article EN Physiologia Plantarum 2008-05-26

Recent years have seen an upsurge of interest in brown adipose tissue (BAT) to combat the epidemic obesity and diabetes. How its development activation are regulated at posttranscriptional level, however, has yet be fully understood. RNA binding proteins (RBPs) lie center regulation. To systemically study role RBPs BAT, we profiled >400 different depots identified Y-box protein 2 (Ybx2) as a novel regulator BAT activation. Knockdown Ybx2 blocks adipogenesis, whereas overexpression...

10.2337/db17-0655 article EN Diabetes 2017-09-29

The epidemic of obesity and diabetes has markedly spurred the research interest in adipocyte biology. Brown adipocytes are specialized for energy expenditure therapeutic treatment metabolic diseases, but how brown distinguished from white at level translational regulation remains poorly understood. To systemically determine control gene expression adipose tissue, we performed ribosome profiling RNA-seq parallel to depict translatome transcriptome changes during primary adipogenesis, between...

10.1038/s41598-017-06077-3 article EN cc-by Scientific Reports 2017-07-12

Microsatellite FSHBMS polymorphism at the 5' flanking region of FSHB gene was genotyped and associations with reproductive traits in several pig populations tract components Large White × Meishan F2 offspring were studied. The results showed that allele 98 carriers had a non-significantly higher total number born alive multiple parities; 118/118 animals significantly piglets weaning than 98/98 98/118 (P < 0.05) litter weight individual 0.05). shortest gestation length 0.05); uterine horns...

10.17221/371-cjas article EN cc-by-nc Czech Journal of Animal Science 2008-04-30

A sensitive and rapid ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed to determine nintedanib in mice plasma using diazepam as the internal standard (IS).

10.1039/c5ay01207d article EN Analytical Methods 2015-01-01

Experimental animalsIn this study, 44 Meishan pigs (a native Chinese breed), 36 Large white pigs, 66 Line DIV 127 white× resource family F 2 offspring were bred and raised at the genetic nucleus station owned by Huazhong Agricultural University.Twenty-one Tongcheng 30 Erhualian derived from (Tongcheng, Hubei Province) Houqiao (Xishan, Jiangshu research farms in China, respectively.The purebred Qingping animals used study born farm of province China.At farrowing, total number (TNB) piglets...

10.5713/ajas.2006.632 article EN cc-by Asian-Australasian Journal of Animal Sciences 2006-03-29

Although long noncoding RNAs (lncRNAs) experience weaker evolutionary constraints and exhibit lower sequence conservation than coding genes, they can still conserve their features in various aspects. Here, we used multiple approaches to systemically evaluate the between human mouse lncRNAs from dimensions including sequences, promoter, global synteny, local which led identification of 1,731 conserved with 427 high-confidence ones meeting criteria. Conserved lncRNAs, compared non-conserved...

10.26508/lsa.202302002 article EN cc-by Life Science Alliance 2023-04-05

By screening a subtracted cDNA library constructed with mRNA obtained from the longissimus dorsi muscles of F1 hybrids Landrace×Yorkshire and their Yorkshire female parents, we isolated two partial sequences coding for H3-K4-specific methyltransferase (KIAA1717) skeletal muscle myosin regulatory light chain (HUMMLC2B) genes.In present work investigated SNPs, one (C1354T) at 3' untranslated region (UTR) KIAA1717 (A345G) SINE (PRE-1) element HUMMLC2B, in resource population derived crossing...

10.5713/ajas.2005.1519 article EN cc-by Asian-Australasian Journal of Animal Sciences 2005-12-02

Objective: To evaluate the accommodative response of patients with intermittent exotropia (IXT) objectively, and study changes when maintaining binocular fusion. Methods: The prospective cohort was used in this study. Twenty-four diagnosed basic who visited eye hospital Wenzhou Medical University during October 2016 through January 2017 together 24 normal volunteers were included, 48 participants aged from 10 to 27 years old. divided into case group control group. There 11 males 13 females...

10.3760/cma.j.issn.0412-4081.2018.01.010 article EN PubMed 2018-01-11

Purpose This study investigated the effect of simplified and traditional chinese character on accommodative lag, accommodation microfluctuation, near work-induced transient myopia (NITM) during task as well subsequent decay time. We aimed to analyze if Chinese had trend inducing progress. Methods Young adults were classified into emmetropes myopes . Two size (12pt,8pt) two type (simplified character) used give four different reading targets computer screen. It was presented in random order...

10.1111/j.1755-3768.2012.f062.x article EN Acta Ophthalmologica 2012-08-06

Objective To investigate the effect of simplified and traditional Chinese characters on near work-induced transient myopia (NITM) its subsequent decay in myopes emmetropes.Methods In an experimental study,young adult subjects (18-28 years) were classified into two groups based their refractive errors: emmetropes (n=18) (n=18).Two sizes (12 pt,8 pt) types (simplified characters) used to provide four different reading targets computer screen.Targets presented random order at 40 cm (2.5...

10.3760/cma.j.issn.1674-845x.2012.10.002 article EN Chinese Journal of Optometry & Ophthalmology 2012-10-25

Objective To analyze the accommodative parameters between anisometropes and emmetrope to see if accommodation are risk factor for myope progression.Methods Fourty subjects,20 anisometrope 20 emmetrope,the AMP lag NRA/PRA were measured after distance refractive correction.Results There no significant differences in NRA three groups.The PRA of was(-5.462±1.2651)D,the anisometrpe was(-3.350±1.7404)D.The was significantly lower than that emmetrope(P = 0.026).The ofemmetrope...

10.3760/cma.j.issn.1006-4443.2009.08.009 article EN Chinese Journal of Practical Ophthalmology 2009-08-10
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