- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Renal Transplantation Outcomes and Treatments
- Histone Deacetylase Inhibitors Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Organ Transplantation Techniques and Outcomes
- Acute Myeloid Leukemia Research
- Transplantation: Methods and Outcomes
Shanghai Children's Medical Center
2024
Shanghai Clinical Research Center
2024
Second Affiliated Hospital of Nanjing Medical University
2020
Hypothermia is commonly used to protect donor hearts during transplantation. However, patients transplanted with aged still have severe myocardial injury and decreased survival rates, but the underlying mechanism remains unknown. Because are not considered suitable for donation, number of awaiting heart transplants increasing. In this study, we examined whether hypothermic cardioprotection was attenuated in transplantation evaluated potential therapeutic targets. Using a rat model, found...
Abstract Background and Aims Patients with acute myeloid leukaemia (AML) suffer from severe myocardial injury during daunorubicin (DNR)-based chemotherapy are at high risk of cardiac mortality. The crosstalk between tumour cells cardiomyocytes might play an important role in chemotherapy-related cardiotoxicity, but this has yet to be demonstrated. This study aimed identify its underlying mechanism explore potential therapeutic targets. Methods Cardiac tissues were harvested AML patient after...
Abstract Background: The levels of serum D-dimer (D-D) in children with Mycoplasma pneumoniae pneumonia (MPP) were assessed to explore the clinical significance D-D refractory MPP (RMPP). Method: A total 430 patients enrolled between January 2015 and December divided into a general (GMPP) group (n=306) RMPP (n=124). Clinical data, level, white blood cell (WBC) count, proportion neutrophils (N%), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT),...
Abstract Background: The levels of serum D-dimer (D-D) in children with Mycoplasma pneumoniae pneumonia (MPP) were assessed to explore the clinical significance D-D refractory MPP (RMPP). Method: A total 430 patients enrolled between January 2015 and December divided into a general (GMPP) group (n=306) RMPP (n=124). Clinical data, level, white blood cell (WBC) count, proportion neutrophils (N%), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT),...
Abstract Background: The levels of serum D-dimer (D-D) in children with Mycoplasma pneumoniae pneumonia (MPP) were assessed to explore the clinical significance D-D refractory MPP (RMPP). Method: A total 430 patients enrolled between January 2015 and December divided into a general (GMPP) group (n=306) RMPP (n=124). Clinical data, level, white blood cell (WBC) count, proportion neutrophils (N%), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT),...