A5109103787- Oral Health Pathology and Treatment
- Prostate Cancer Treatment and Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Prostate Cancer Diagnosis and Treatment
- Urinary Bladder and Prostate Research
- Genetic Neurodegenerative Diseases
- Advanced Algorithms and Applications
- Ginseng Biological Effects and Applications
- Civil and Geotechnical Engineering Research
- Ocular and Laser Science Research
- Advanced Image Processing Techniques
- Molecular Biology Techniques and Applications
- vaccines and immunoinformatics approaches
- Laser Material Processing Techniques
- Effects of Radiation Exposure
- RNA modifications and cancer
- Image Processing Techniques and Applications
- CAR-T cell therapy research
- Plant biochemistry and biosynthesis
- E-commerce and Technology Innovations
- Environmental Engineering and Cultural Studies
- RNA regulation and disease
- Salivary Gland Disorders and Functions
Shanghai Jiao Tong University
2005-2025
Shanghai First People's Hospital
2023-2025
Central South University
2024
Fujian Agriculture and Forestry University
2018-2024
University of South China
2023
Heilongjiang Bayi Agricultural University
2023
Shanghai Ninth People's Hospital
1996-2022
The accurate diagnosis of prostate cancer (PCa) remains challenging, particularly because standard biopsy techniques do not routinely include anterior zone, leading to potential missed diagnoses in this region. This study evaluates the accuracy and safety biplanar stereotactic for diagnosing clinically significant PCa (csPCa). After propensity score matching analysis, data from 256 patients were retrospectively analyzed, including 128 group (transrectal targeted with transperineal systematic...
Abstract Myofibroblast buildup and prostatic fibrosis play a crucial role in the development of benign hyperplasia (BPH). Treatments specifically targeting myofibroblasts could be promising approach for treating BPH. Tadalafil, phosphodiesterase type 5 (PDE5) inhibitor, holds potential to intervene this biological process. This study employs stromal fibroblasts induce myofibroblast differentiation through TGFβ1 stimulation. As result, tadalafil significantly inhibited fibroblast...
In response to blue light, cryptochromes photoexcite and interact with signal partners transduce almost synchronously in plants. The detailed mechanism of CRY-mediated light signaling remains unclear: the photobiochemical reactions cryptochrome are transient synchronous, thus making monitoring analysis each step difficult plant cells. this study, we reconstituted Arabidopsis CRY2 pathway mammalian cells investigated biological role heterologous system, eliminating interferences other...
Radiation-induced skin injury (RISI) is a frequent complication of radiotherapy that can severely hinder treatment and endanger patients’ lives. Current treatments offer limited efficacy in reducing symptoms. This study explores the protective effect aspirin (ASP) on RISI its underlying mechanisms. As vivo models, 8 – 12-week-old C57BL/6 mice were irradiated with single dose 20 Gy X-rays to right thigh, sham-irradiated serving as controls. ASP was administered orally for...
In this paper, the song-ordering system designed based on speech recognition uses STM32 single-chip microcomputer as main control unit to realize corresponding functions. The includes design of hardware and realization software rest have LD3320 module, OLED display voice broadcast module song playback module. working process is mainly completed by sending protocol, that is, receives command, serial port sends protocol trigger microcontroller part. meets following functions: it has function...
Immunotherapy resistance is a significant obstacle in the treatment of prostate cancer (PCa), primarily due to immune evasion mechanisms. This study aims explore cancer-intrinsic evasion-related genes (CIERGs) PCa and develop predictive signature for biochemical recurrence (BCR). Bulk RNA-seq data single-cell RNA-sequencing (scRNA-seq) were obtained from TCGA Gene Expression Omnibus database. The scRNA-seq analysis revealed higher scores tumor cells compared normal cells. Differentially...
Heat shock transcription factors (Hsf) are pivotal as essential factors. They function direct transcriptional activators of genes regulated by thermal stress and closely associated with various abiotic stresses. Asparagus (Asparagus officinalis) is a vegetable considerable economic nutritional significance, abundant in vitamins, minerals, dietary fiber. Nevertheless, asparagus sensitive to environmental stresses, specific stresses harm its yield quality. In this context, Hsf members have...
Genistein, an isoflavone present in soy at high concentrations and being considered the primary antitumor constituent soy, has been known to be a natural anticancer agent vitro studies experimental animal models. The study was aimed investigate putative chemopreventive effect of genistein on oral carcinogenesis hamster cheek pouch post-initiation stage, as well its angiogenesis during this process. DMBA solution (0.5% mineral oil) applied topically left male Syrian golden hamsters three...
PD1/PDL1 pathway plays a critical role in cancer immune responses. The checkpoint inhibitors of have been well explored and developed for immunotherapies solid tumors. Recently, various monoclonal antibodies targeting the emerged achieved remarkable success clinical trials. However, challenges with these appeared during therapies, including predictors response, patient selection, innate resistance. Thus, competitive antagonist native PD1/PDL1, smaller size lower side-effect, is required...
Image resizing plays a very important role in image processing, offering good scalability and extensibility. Currently, there are some issues with existing scaling interpolation algorithms, such as complex hardware implementation, high resource consumption, long operation times, poor realtime performance. To address these challenges, this paper introduces design method based on the bicubic algorithm optimizes floating-point aspect of processing. Utilizing FPGA platform, step-by-step approach...
To solve the transmission problem of laser marking instruction and coordinate data in system, a field editable logic device FPGA is proposed to realize Ethernet custom protocol stack. In this paper, system based on designed. The stack defined by reconstructing frames, dual-channel analysis storage instructions are completed. At same time, control module receives multi-channel synchronization signal galvanometer moving platform, realizes nanosecond signal, completes digital adjustable CO <inf...
复发性阿弗他溃疡（recurrent aphthous ulcer，RAU）是最常见的口腔黏膜溃疡类疾病，可显著降低患者的口腔健康水平及生活质量。由于RAU的病因及发病机制尚不明确，目前还没有根治的方法，因此RAU的治疗以对症治疗为主，并将减轻疼痛、促进溃疡愈合、延长复发间歇期作为治疗目的。本文将简述RAU的流行病学及病因学研究进展，复习该疾病的临床表现、分类、诊断及鉴别诊断，并介绍最新的病情评价指标，重点更新RAU疾病管理的研究进展，以期提高口腔医师对RAU的诊疗水平。.