Chun Li

ORCID: 0009-0009-2779-9362
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About
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Research Areas
  • Cardiac Ischemia and Reperfusion
  • Animal Disease Management and Epidemiology
  • S100 Proteins and Annexins
  • Mycobacterium research and diagnosis
  • Clinical Nutrition and Gastroenterology
  • RNA Research and Splicing
  • Neonatal and fetal brain pathology
  • SARS-CoV-2 and COVID-19 Research
  • Cancer-related molecular mechanisms research
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies
  • Influenza Virus Research Studies
  • Viral gastroenteritis research and epidemiology
  • Global Cancer Incidence and Screening
  • RNA modifications and cancer
  • Colorectal Cancer Screening and Detection
  • DNA Repair Mechanisms
  • Circular RNAs in diseases
  • Cardiovascular Function and Risk Factors
  • Prion Diseases and Protein Misfolding
  • Cancer Immunotherapy and Biomarkers
  • Liver physiology and pathology
  • Fatty Acid Research and Health
  • Organ Transplantation Techniques and Outcomes
  • Cancer Risks and Factors

Louisiana State University
2024

Capital Normal University
2024

Louisiana State University Health Sciences Center Shreveport
2024

National Center for Chronic and Noncommunicable Disease Control and Prevention
2023

Chinese Center For Disease Control and Prevention
2023

Southern Medical University
2014-2021

Nanfang Hospital
2021

The First Affiliated Hospital, Sun Yat-sen University
2020

Zhongshan Hospital
2020

Fudan University
2020

Owing to incurable castration-resistant prostate cancer (CRPC) ultimately developing after treating with androgen deprivation therapy (ADT), it is vital devise new therapeutic strategies treat CRPC. Treatments that target programmed cell death protein 1 (PD-1) and ligand-1 (PD-L1) have been approved for human cancers clinical benefit. However, many patients, especially cancer, fail respond anti-PD-1/PD-L1 treatment, so an urgent need seek a support strategy improving the traditional...

10.1016/j.apsb.2021.07.016 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2021-07-21

SummaryBackgroundThe outbreak of COVID-19 has led to international concern. We aimed establish an effective screening strategy in Shanghai, China, aid early identification patients with COVID-19.MethodsWe did a multicentre, observational cohort study fever clinics 25 hospitals 16 districts Shanghai. All visiting the within period were included. A for was presented and then suspected cases monitored analysed until they confirmed as or excluded. Logistic regression used determine risk factors...

10.1016/s2589-7500(20)30109-6 article EN cc-by The Lancet Digital Health 2020-05-15

ABSTRACT Periodontitis, a common chronic inflammatory disease of the periodontium, is caused by dental plaque formation induced microorganisms. Recent studies have demonstrated that lncRNAs play critical role in regulation gene expression and pathogenesis diseases. To demonstrate periodontitis associated with lncRNAs, microarray analysis was used to detect differently expressed adjacent normal tissues. The results some were further confirmed using real‐time PCR. A total 8925 differentially...

10.1002/jcb.25015 article EN Journal of Cellular Biochemistry 2014-11-17

<abstract abstract-type="Summary"> <sec> <b>What is already known about this topic?</b> In 2015, only 18.9% of adult women underwent breast cancer screening in China. </sec><sec> added by report?</b> Breast coverage for aged 20 years and above China reached 22.3% during 2018–2019. Women with lower socioeconomic status had coverage. There were significant variations across the provincial-level administrative divisions. are implications public health practice?</b> The promotion requires...

10.46234/ccdcw2023.062 article EN China CDC Weekly 2023-01-01

Cardiopulmonary arrest (CA) is a major cause of death/disability in the U.S. with poor prognosis and survival rates. Current therapeutic challenges are physiologically complex because they involve hypoperfusion (decreased cerebral blood flow), neuroinflammation, mitochondrial dysfunction. We previously discovered novel serum/glucocorticoid-regulated kinase 1 (SGK1) highly expressed brain neurons that susceptible to ischemia (hippocampus cortex). inhibited SGK1 utilized pharmacological...

10.1177/0271678x231224508 article EN Journal of Cerebral Blood Flow & Metabolism 2024-01-18

DNA polymerase ζ (Pol ζ) plays an essential role in replicating damaged templates but contributes to mutagenesis due its low fidelity. Therefore, ensuring tight control of Pol ζ's activity is critical for continuous and accurate replication, yet the specific mechanisms remain unclear. This study reveals a regulation mechanism human cells. Under normal conditions, autoinhibition keeps catalytic subunit, REV3L, inactive. Upon encountering replication stress, however, ATR-mediated...

10.1038/s41467-024-52112-z article EN cc-by-nc-nd Nature Communications 2024-08-30

10.1360/ssv-2021-0098 article EN Scientia Sinica Vitae 2021-08-24
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