Breastfeeding rates remain low in China and some mothers stop breastfeeding shortly after returning to work. Our study aimed investigate the association between practices of working their employment status (formal versus informal) occupational fields (agriculture related, industry business white collar). We also identified key work-related factors that influence Chinese mothers.This is a mixed-method research consisted two components. conducted cross-sectional 10,408 with children under 12...

Background: Myopia is one of the most common causes vision impairment in children and adults has become a public health priority with its growing prevalence worldwide. This study aims to identify evaluate global trends myopia research past century visualize frontiers using bibliometric analysis. Methods The literature search was conducted on Web Science for studies published between 1900 2020. Retrieved publications were analyzed in-depth by annual publication number, prolific countries...

Screen time is becoming increasingly common in daily life. Early and excessive screen use has raised growing concerns for children's neuropsychological development. The purpose of this study was to evaluate the association between exposure early life presence autistic-like behaviors among preschool children. 29,461 child-caregiver dyads at kindergartens Longhua New District Shenzhen, China, were enrolled cross-sectional study. Information concerning socio-demographic characteristics,...

Understanding of the mechanism underlying pathogenesis or protection for influenza-Streptococcus pneumoniae coinfected pneumonia provides potential strategy in decreasing high morbidity and mortality this infectious disease. Interleukin-6 (IL-6) is an important cytokine to limit infection-related inflammation; however, its role remains unclear. Here we show that patients with displayed dramatically elevated IL-6 levels; similarly, clinically relevant mice had increased production lung...

Temporomandibular joint (TMJ) osteoarthritis with pain is a highly prevalent disorder affecting patients' quality of life. A comprehensive understanding cell type diversity and its dynamics in painful TMJ (TMJOA) lacking. Here, we utilized an inflammatory TMJOA mouse model via intra-articular injection CFA. mice exhibited cartilage remodeling, bone loss, synovitis, increased (OA) score, orofacial pain, recapitulating hallmark symptoms patients. Single-cell transcriptomic profiling the was...

Ferroptosis, a newly discovered form of regulated cell death, has garnered significant attention in the field tumor therapy. However, presence overexpressed glutathione (GSH) and insufficient levels H2O2 microenvironment (TME) hinders occurrence ferroptosis. In response to these challenges, here we have constructed self-assembled nanocomplexes (FeE NPs) utilizing epigallocatechin-3-gallate (EGCG) from green tea polyphenols metal ions (Fe3+) as components. After grafting PEG, (FeE@PEG exhibit...

Influenza is a major public health threat, and vaccination the most effective prevention method. However, coverage remains suboptimal. Low literacy regarding influenza may contribute to vaccine hesitancy. This study aims evaluate effect of education interventions on rates literacy. cluster randomised controlled trial will enrol 3036 students in grades 4-5 from 20 primary schools Dongguan City, China. Schools be an intervention group receiving or control routine education. The outcome rate....

BACKGROUND Primary sclerosing cholangitis (PSC) is a long-term liver condition defined by the inflammation and scarring of bile ducts, resulting in complications such as cirrhosis, portal hypertension, cholangiocarcinoma. Although PSC predominantly affects adults, incidence pediatric patients rising. For individuals advanced stages disease, transplantation (LT) sole curative treatment option. However, recurrence transplanted liver, known recurrent (rPSC), remains significant concern. AIM To...

<title>Abstract</title> Temporomandibular joint (TMJ) arthritis is a craniofacial disorder characterized by dysfunction and orofacial pain. Lymphatic regulation function in the TMJ remain unknown. Using genetic reporter mice, human tissues, tissue clearing, 3D volume imaging, functional studies, we identified synovial lymphatic system TMJ. In mouse model of arthritis, inflammation induces extensive remodeling leads to dysfunctions, including decreases efflux lymph node fluid drainage....

The prevalence of allergic disorders is increasing around the world. This study used standardized written questionnaire from International Study Asthma and Allergies in Childhood (ISAAC, phase III) to collect two cross-sectional appraisals schoolchildren 5 years apart–one performed 2002 another on 2007, focus secular trends allergies central Taiwan. was administered over 46 schools across Changhwa County 2002, again 2007. present a follow-up uses data collected previously reported conducted...

This study aimed to provide updated information on biopsied oral and maxillofacial (OMF) pediatric lesions in Southern Taiwan. The data were compared with our previous (1985–1996) also studies from Northern Taiwan other countries. Biopsied cases a population (0–15 years old), between 1997 2011, retrieved the Oral Pathology Department of institution. Age, sex, location, histological diagnoses recorded. divided into three age levels: 0–5 years, 6–10 11–15 years. OMF classified four categories:...

Research into early screen exposure has raised growing concerns about its impact upon children’s neuropsychological well-being. However, possible pathways remain unclear. This study therefore aimed not only to evaluate the association between during ages of 0–3 years and preschoolers’ autistic-like behaviors, but also mediating roles frequency caregiver-child interaction, sleep duration level participation in outdoor activities. Based on 2017 survey Longhua Child Cohort Study, data 29,595...

China has a high burden of cervical cancer (CC) and wide disparities in CC exist among different socio-economic regions. In order to reduce these disparities, China's government launched the National Cervical Cancer Screening Program Rural Areas (NCCSPRA) 2009. Understanding factors associated with underutilization screening target populations is important improve participation rate, rate key achieving goals program. However, data on knowledge program areas lacking China. This study will...

Associations between dietary patterns (DPs) and sarcopenia remain controversial, fewer studies have mentioned the relationship energy composition sarcopenia. The present cross-sectional study was conducted in three regions of China, to detect associations DPs sarcopenia, identify influencing nutrients. Exploratory factor analysis for DP identification. Logistic regressions were performed explore Dietary nutrients calculated compared among different DPs. Three identified from 861...

Temporomandibular joint (TMJ) pain and osteoarthritis (OA) are common debilitating disorders that impair patients' quality of life. The mechanisms driving diseases-related poorly understood, current treatments fail to provide effective long-term therapeutic effects. Additionally, assessment in research, particularly orofacial pain, poses several challenges complicate studies both clinical basic science settings. Therefore, we have established an inflammatory TMJ mouse model via...

A study of the whole spectrum biopsied head and neck (HN) diseases in Taiwan has not yet been performed. Therefore, current aimed to provide updated information about HN lesions a cohort referral Taiwanese patients for histopathological examination. (2000–2011) with records age, sex, histological diagnoses were retrieved from Oral Pathology Department institution. These classified into four main categories: tumor/tumor-like reactive lesions, cystic/pseudocystic inflammatory/infective...

This study aimed to investigate the association between prenatal education and autistic-like behaviors of preschoolers as well mediating role breastfeeding in their associations. A cross-sectional via a structured questionnaire was conducted with 67,578 preschool children parents from Longhua District Shenzhen, China. Hierarchical logistic regression models were performed explore associations maternal participation preschoolers, effect After controlling for potential confounders, analysis...

Postoperative performance, including best corrected distance visual acuity (BCDVA) and optical metrics (from the OQAS iTrace devices), was compared among 4 different intraocular lenses (IOLs).

Cascade analysis is an effective method to analyze the processing data of event, such as a provided service or series examinations. This study aimed develop primary cervical cancer screening cascade in China promote quality process.We designed according program flow chart. It had three stages, each with two steps and one result. Data from 117,522 women aged 35 64 years Rural Cervical Cancer Surveillance Project January 1, 2014, December 31, were collected main results cascade. The proportion...