- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
- Renal Diseases and Glomerulopathies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Dialysis and Renal Disease Management
- Hemodynamic Monitoring and Therapy
- Platelet Disorders and Treatments
- Acute Ischemic Stroke Management
- Intensive Care Unit Cognitive Disorders
- Pressure Ulcer Prevention and Management
- Anesthesia and Neurotoxicity Research
- Sleep and Wakefulness Research
- Wound Healing and Treatments
- Neonatal skin health care
Xi'an Jiaotong University
2025
Mudanjiang Medical University
2023
Southern Medical University Shenzhen Hospital
2023
Guangdong Academy of Medical Sciences
2020
Guangdong Provincial People's Hospital
2020
Zhengzhou University
2020
Continuous renal replacement therapy (CRRT) is widely used for treating critically-ill patients in the emergency department China. Anticoagulant needed to prevent clotting extracorporeal circulation during CRRT. Regional citrate anticoagulation (RCA) has been shown potentially be safer and more effective now recommended as preferred anticoagulant method However, there still a lack of unified standards RCA management world, are many problems using this clinical practice. The Emergency Medical...
Autophagy-lysosomal pathway dysfunction leads to postoperative cognitive (POCD). Dexmedetomidine (Dex) improves POCD, and we probed the effects of Dex on autophagy-lysosomal in a POCD model. A mouse model was established intraperitoneally injected with Dex. Cognitive function evaluated by Morris water maze/open field test/novel object recognition assay. Levels neurotransmitters/inflammatory cytokines hippocampus, NLRP3/ASC/Cleaved Caspase-1 proteins were determined ELISA/Western blot. NLRP3...
Abstract Background The definitions of contrast-associated acute kidney injury (CA-AKI) are diverse and have different predictive effects for prognosis, which adverse clinical practice. Few articles discussed the relationship between these long-term prognosis in patients with diabetes. Methods A total 1154 diabetic who were undergoing coronary angiography (CAG) included this study. Two CA-AKI used: was defined as an increase ≥ 0.3 mg/dl or > 50% serum creatinine (SCr) from baseline within...
Diabetic kidney disease (DKD) is one of the most common complications diabetes, and cause end-stage renal disease, for which no effective therapies are yet available. RNA-binding proteins (RBPs) play a pivotal role in epigenetic regulation; tristetraprolin (TTP) human antigen R (HuR) competitively bind cytokine mRNAs, exert contrasting effects on RNA stability, drive inflammation. However, RBPs’ roles diabetes-related glomerulopathy poorly understood. Herein, we investigated whether TTP HuR...