A5101679535- Genomic variations and chromosomal abnormalities
- Chromosomal and Genetic Variations
- T-cell and B-cell Immunology
- Antifungal resistance and susceptibility
- Genomics and Phylogenetic Studies
- Mycorrhizal Fungi and Plant Interactions
- Respiratory and Cough-Related Research
- Forest Ecology and Biodiversity Studies
- Forest Insect Ecology and Management
- Genomics and Chromatin Dynamics
- vaccines and immunoinformatics approaches
- Immunotherapy and Immune Responses
- Asthma and respiratory diseases
Peking University People's Hospital
2022-2023
Peking University
2022-2023
Shenzhen Institutes of Advanced Technology
2015
Chinese Academy of Sciences
2015
Since its initial release in 2001, the human reference genome has undergone continuous improvement quality, and recently released telomere-to-telomere (T2T) version - T2T-CHM13 reaches highest level of continuity accuracy after 20 years effort by working on a simplified, nearly homozygous hydatidiform mole cell line. Here, to provide an authentic complete diploid for Han Chinese, largest population world, we assembled male Chinese individual, T2T-YAO, which includes T2T assemblies all 22 + X...
While the duration and size of human clinical trials may be difficult to reduce, there are several parameters in pre-clinical vaccine development that possible further optimise. By increasing accuracy models used for testing, it should increase probability any particular candidate will successful trials. In addition, an improved model allow collection increasingly more-informative data tests, thus aiding rational design formulation candidates entered into evaluation. An acceleration...
Abstract Since its initial release in 2001, the human reference genome has been continuously improved both continuity and accuracy, recently-released telomere-to-telomere version—T2T-CHM13—reaches top quality after 20 years of effort. However, T2T-CHM13 does not represent an authentic diploid genome, but rather one derived from a simplified, nearly homozygous hydatidiform mole cell line. To address this limitation provide alternative pertinent to Chinese population, largest ethnic group...
Allergic bronchopulmonary aspergillosis (ABPA) primarily complicates the course of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). Mortality data ABPA difference in all-cause mortality between with without COPD are not available.We investigated COPD.A retrospective review was performed among patients diagnosis at Peking University People's Hospital January 2010 March 2022. Logrank test to investigate for Cox regression analysis independent risk factors...