Ding Lei

ORCID: 0009-0009-9215-9548
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About
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Research Areas
  • Epilepsy research and treatment
  • Pharmacological Effects of Natural Compounds
  • Natural Compounds in Disease Treatment
  • Pharmacological Effects and Toxicity Studies
  • Infectious Encephalopathies and Encephalitis
  • Cancer, Hypoxia, and Metabolism
  • Medical Research and Treatments
  • Glioma Diagnosis and Treatment
  • Coronary Interventions and Diagnostics
  • Botulinum Toxin and Related Neurological Disorders
  • Drug Transport and Resistance Mechanisms
  • Herpesvirus Infections and Treatments
  • Endometriosis Research and Treatment
  • Medical Imaging and Analysis
  • Cardiac Arrhythmias and Treatments
  • Autoimmune Bullous Skin Diseases
  • RNA regulation and disease
  • Healthcare and Venom Research
  • Apelin-related biomedical research
  • Neurological Disease Mechanisms and Treatments
  • Ion channel regulation and function
  • Pharmaceutical Economics and Policy
  • Biological Stains and Phytochemicals
  • Neuroscience and Neuropharmacology Research
  • Antiplatelet Therapy and Cardiovascular Diseases

First Affiliated Hospital of Henan University of Traditional Chinese Medicine
2025

Qingdao University
2021

Qingdao Municipal Hospital
2021

Sichuan University
2011-2018

West China Hospital of Sichuan University
2011-2018

Peking University
2014

Peking University Third Hospital
2014

Xian Central Hospital
2013

Yinchuan First People's Hospital
2008

Pemphigus is a group of rare life-threatening mucocutaneous autoimmune diseases, presenting mainly as two subtypes: pemphigus vulgaris (PV) and foliaceus (PF). Inherited predispositions to have long been speculated but they remain poorly understood.To identify common specific nongenetic genetic factors associated with its subtypes in the Chinese population.A genome-wide association study (GWAS) was performed 496 unrelated patients (including 365 PV 104 PF) 1105 controls without pemphigus.A...

10.1111/bjd.17191 article EN British Journal of Dermatology 2018-09-19

Introduction Inflammatory bowel disease (IBD) includes Crohn’s (CD) and ulcerative colitis (UC). Epidemiological studies have found that patients with IBD are more likely to suffer from cardiovascular diseases (CVDs) than the general population. However, so far, no exact causal association has been demonstrated between CVDs, research is needed clarify this relationship. Material methods The two-sample Mendelian randomization (MR) method was used explore effect of on CVDs. exposure factor...

10.5114/aoms/204370 article EN cc-by-nc-sa Archives of Medical Science 2025-05-27

Polymorphism and the ossification of ligaments deletion IVS20 or AA genotype A533C had an approximately 3 times greater chance not having than disease progression after surgery.We concluded that 4 SNPs analyzed appeared to have different effects on etiology pathology OPLL.To our knowledge, this study is first investigate relationship between these surgery.Our findings suggest presence specific genotypes IVS20-11delT may predict outcome surgical intervention.

10.4238/2013.october.18.3 article EN Genetics and Molecular Research 2013-01-01

Pregabalin (PGB) is a novel antiepileptic drug and also used as first-line medication for the treatment of neuropathic pain. However, mechanisms its analgesic effects remain largely unknown.To elucidate underlying antiallodynic action PGB in rats with pain.In rat model pain induced by spared nerve injury, mechanical allodynia, behavioural sign pain, was assessed measuring 50% paw withdrawal threshold von Frey filaments. Activities dorsal horn wide dynamic range (WDR) neurons were examined...

10.1155/2014/623830 article EN cc-by Pain Research and Management 2014-01-01
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