A5066209833- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Pulmonary Hypertension Research and Treatments
- Dialysis and Renal Disease Management
- Frailty in Older Adults
- Coronary Artery Anomalies
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Disease Management Strategies
- Heart Failure Treatment and Management
- Retirement, Disability, and Employment
- Venous Thromboembolism Diagnosis and Management
- Chronic Kidney Disease and Diabetes
- Renin-Angiotensin System Studies
- Blood Pressure and Hypertension Studies
- Global Health and Epidemiology
- Childhood Cancer Survivors' Quality of Life
- Erythropoietin and Anemia Treatment
- Travel Writing and Literature
- Hemodynamic Monitoring and Therapy
- Infant Development and Preterm Care
Utrecht University
2024
University Medical Center Groningen
2007-2015
Friedrich-Alexander-Universität Erlangen-Nürnberg
2014
A main challenge for targeting chronic kidney disease (CKD) is the heterogeneity of its causes, co-morbidities and outcomes. Patients under nephrological care represent an important reference population, but knowledge about their characteristics limited. We enrolled 5217 carefully phenotyped patients with moderate CKD [estimated glomerular filtration rate (eGFR) 30–60 mL/min per 1.73 m2 or overt proteinuria at higher eGFR] routine nephrologists into German Chronic Kidney Disease (GCKD)...
Erythropoietin (EPO) mobilises endothelial progenitor cells and promotes neovascularisation in heart failure. The present authors studied the effects of EPO on pulmonary vascular cardiac remodelling a model for flow-associated arterial hypertension (PAH). PAH was induced adult male Wistar rats by injection monocrotaline combined with an abdominal aortocaval shunt 1 week later (PAH or experimental group). Immediately afterwards, were randomised into those who received treatment (PAH+EPO...
Primary chronic kidney disease is associated with high cardiovascular risk. However, the exact mechanisms behind this cardiorenal interaction remain unclear. We investigated between heart and kidneys in novel animal model for interaction. Normal Wistar rats Munich Fromter rats, spontaneously developing renal dysfunction, were subjected to experimental myocardial infarction induce cardiac dysfunction (CD) combined (CRD), respectively (N = 5-10). Twelve weeks later, cardiac- parameters...
Global Heart is the official and primary publication of World Federation, offering a platform for dissemination knowledge on research, developments, trends, solutions public health programmes in area cardiovascular disease. welcomes research results, points view educational material prevention, treatment control disease with special focus low middle-income countries which are facing brunt epidemiological transition.Global strongly encourages authors to adhere CONSORT, STROBE, STARD, PRISMA...
<title>Abstract</title> Background The demand for managing congenital heart disease (CHD) exceeds the available resources in low- and middle-income countries (LMICs). This has resulted a growing population of children with CHD, only few receiving surgical interventions, while many more are waiting intervention. Health-related quality life (HRQOL) its impact on pediatric CHD these settings have been largely overlooked, limited research conducted. Therefore, this study aimed to explore HRQOL...
<title>Abstract</title> Background The Pediatric Quality of Life Inventory™ (PedsQL™) Family Impact Module, a valuable assessment tool for health-related quality (HRQoL), is not accessible in Swahili. This study evaluated the construct validity PedsQL™ Module assessing HRQoL Swahili speakers Eastern Africa, Tanzania, particularly focusing on families chronic congenital heart disease (CHD) with both operated and unoperated children. Methods cross-sectional involved primary caregivers at...