A5004707324- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Trypanosoma species research and implications
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Viral Infections and Immunology Research
- Healthcare during COVID-19 Pandemic
- Women's cancer prevention and management
- Healthcare Regulation
- Chemotherapy-induced cardiotoxicity and mitigation
- Cervical Cancer and HPV Research
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Iron Metabolism and Disorders
- Cardiac pacing and defibrillation studies
- Science and Education Research
- Peripheral Artery Disease Management
- Coenzyme Q10 studies and effects
- Sports Performance and Training
- Physical Education and Gymnastics
- Youth, Drugs, and Violence
Universidade de São Paulo
2011-2024
Universidade Federal do Triângulo Mineiro
2018-2024
Clinics Hospital of Ribeirão Preto
2014-2018
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018
Universidade de Uberaba
2015-2017
Universidade Brasil
2015-2016
Universidade de Ribeirão Preto
2013-2015
Chronic heart failure (HF) is a syndrome characterized by reduced cardiac output in relation to the metabolic needs of organism, as well and neurohormonal axis abnormalities. Symptoms such fatigue dyspnoea are notorious stress tests widely used assess functional capacity, prognosis effectiveness therapeutic interventions this syndrome.To evaluate reproducibility six-minute walk test (6MW) patients with HF correlate magnitude variables reached at peak exercise 6MWT cardiopulmonary (CPET).We...
Background Chronic Chagas cardiomyopathy in humans is characterized by segmental left ventricular wall motion abnormalities ( WMA ), mainly the early stages of disease. This study aimed at investigating detection and its correlation with underlying histopathological changes a chronic model hamsters. Methods Results Female Syrian hamsters (n=34) infected 3.5×10 4 or 10 5 blood trypomastigote Trypanosoma cruzi (Y strain) forms an uninfected control group (n=7) were investigated. After 6 months...
Altered myocardial perfusion is a common finding in chronic Chagas cardiomyopathy (CCC), but its underlying histologic changes have not been elucidated. We investigated the occurrence of defects (MPDs) and correlated regional to histology an experimental model CCC hamsters. <b>Methods:</b> Female Syrian hamsters (<i>n</i> = 34) were infected with 3.5 × 10<sup>4</sup> 10<sup>5</sup> trypomastigote forms <i>Trypanosoma cruzi,</i> Y strain, 6–10 mo afterward underwent vivo imaging including...
Chronic Chagas cardiomyopathy (CCC) is caused by an inflammatory process induced Trypanosoma cruzi, which leads to myocarditis with reactive and reparative fibrosis. CCC progresses myocardial perfusion abnormalities histopathological events that affect cardiorespiratory fitness (CRF).
Fundamento: Técnicas de imageamento in vivo permitem avaliar sequencialmente a morfologia e função dos órgãos em diversos modelos experimentais.Desenvolvemos um dispositivo adaptação uma gama-câmara clínica para obter imagens tomográficas por emissão fótons singulares (SPECT) alta resolução, baseado colimador pinhole.Objetivo: Determinar acurácia desse sistema na quantificação da área infarto miocárdico ratos.Métodos: Treze ratos Wistar machos (250 g) foram submetidos do miocárdio oclusão...
Heart failure induced by myocardial infarct (MI) attenuates the heart rate variability (HRV) and baroreflex sensitivity, which are important risk factors for life-threatening cardiovascular events. Therapies with mesenchymal stem cells (MSCs) have shown promising results after MI. However, effects of MSCs on hemodynamic (heart arterial pressure) sensitivity in chronic (CHF) following MI not been evaluated thus far. Male Wistar rats received or saline solution intravenously 1 week ligation...
Determination of left ventricular ejection fraction (LVEF) using in vivo imaging is the cardiac functional parameter most frequently employed preclinical research. However, there considerable conflict regarding effects anesthetic agents on LVEF. This study aimed at assessing various LVEF hamsters transthoracic echocardiography. Twelve female were submitted to echocardiography separated by 1-week intervals under following conditions: 1) conscious animals, 2) animals anesthetized with...
Este é um estudo quantitativo realizado de 2015 a 2018, com o objetivo investigar as relações entre sintomas depressivos, intensidade da dor e impacto fibromialgia na qualidade vida em mulheres. Foram avaliadas 90 mulheres fibromialgia, utilizando Escala analógica visual, Depressão Beck Fibromyalgia Impact Questionnaire. A média escala visual foi 6,75 do Questionnaire 61,43. Quanto aos 26,7% apresentaram moderados, 22,2% leves 11,1% graves. Houve correlação inversa fraca idade moderada vida....
Background: Radionuclide ventriculography (RV) is a validated method to evaluate the left ventricular systolic function (LVSF) in small rodents. However, no prior study has compared results of RV with those obtained by other imaging methods this context. Objectives: To compare LVSF and echocardiography (ECHO) an experimental model cardiotoxicity due doxorubicin (DXR) rats. Methods: Adult male Wistar rats serving as controls (n = 7) or receiving DXR 22) accumulated doses 8, 12, 16 mg/kg were...
The objective of this report is to document the effects an aerobic training program on myocardial perfusion, and endothelial function abnormalities, relief angina in a patient with microvascular ischemia. A 53-year-old female exhibited precordial pain effort angiographically normal coronaries. Her symptoms had been present for 4 yrs despite pharmacologic treatment control risk factors, perfusion scintigraphy revealing extensive reversible defect. She was submitted mos, obtaining significant...
The study of myocardial contractility, based on the new anatomical concepts that govern cardiac mechanics, represents a promising strategy analysis adaptations related to physical training in context post-infarction. We investigated influence aerobic capacity and evaluation parameters left ventricular contraction mechanics patients with infarction. Thirty-one (55.1 ± 8.9 years) who had infarction anterior wall were prospectively three groups: interval group (ITG) (n = 10), moderate (MTG) n...
This study aimed to analyze the agreement between measurements of unloaded oxygen uptake and peak based on equations proposed by Wasserman real directly obtained with ergospirometry system. We performed an incremental cardiopulmonary exercise test (CPET), which was applied two groups sedentary male subjects: one apparently healthy group (HG, n=12) other had stable coronary artery disease (n=16). The mean age in HG 47±4 years that (CG) 57±8 years. Both CPET a cycle ergometer ramp-type...
Introduction: Human papillomavirus (HPV), belonging to the Papovavirida family, is most prevalent sexually transmitted disease (STD) agent worldwide. In Brazil, it estimated that there are 3-6 million people infected with HPV. Aim: The aim of this study was evaluate knowledge young male students about penis cancer related HPV infection. Methods: This exploratory and quantitative conducted analyze answers 242 attending a private college located in Uberaba city, Minas Gerais state, during...
Patients with primary microvascular angina (PMA) commonly exhibit abnormal left ventricular function (LVF) during exercise, potentially owing to myocardial ischemia. Herein, we investigated in PMA patients the effect of reduction perfusion disorders, by using aerobic physical training, upon LVF response exercise.Overall, 15 (mean age, 53.7±8.9 years) and healthy controls 51.0±9.4 were studied. All subjects subjected baseline resting exercise ventriculography, scintigraphy (MPS),...
Abstract Background Exploring experimental models of heart failure with preserved ejection fraction (HFpEF) may help to understand the mechanisms leading this challenging condition. Purpose In a translational model, we aimed assess relative contribution hypertension and obesity in inducing structural, functional hemodynamic changes associated HFpEF phenotype. Methods We investigated 3 groups male 40 weeks old rats: control Wistar Kyoto (WKY, n=10), Spontaneous Hypertensive Rats (SHR, n=10)...
Objective: to evaluate the predictors of quality life in workers with Repetitive Strain Injuries/Work-Related Musculoskeletal Disorders. Método: a descriptive, cross-sectional study an exploratory and quantitative methodology 2019. Sociodemographic aspects, intensity musculoskeletal symptoms, emotional comorbidities, were evaluated. Linear regression analysis was performed identify domains. Results: total 68 participated, average age 50.1±7.25 years. The lowest mean score for Physical Domain...
Abstract Background: Chronic Chagas cardiomyopathy (CCC) is caused by an inflammatory process induced Trypanosoma cruzi, which leads to myocarditis with reactive and reparative fibrosis. CCC progresses myocardial perfusion abnormalities histopathological events that affect cardiorespiratory fitness (CRF). Objectives: We evaluated the effects of aerobic physical training (APT) on morphological functional impairments related inflammation fibrosis in Syrian hamsters CCC. As a secondary...
ABSTRACT BACKGROUND: Detraining can partially or completely reduce training-induced metabolic adaptations. However, the duration for which rehabilitation effects persist after detraining, especially in patients with heart disease, remains unclear. OBJECTIVES: To evaluate principle of reversibility/detraining disease via 6-minute walk test (6MWT) a period rest. DESIGN AND SETTING: A retrospective cohort study developed at Rehabilitation Center Universidade Federal do Triângulo Mineiro...