- Genetic and phenotypic traits in livestock
- Lipoproteins and Cardiovascular Health
- Soil erosion and sediment transport
- Irrigation Practices and Water Management
- Animal Behavior and Welfare Studies
- Reproductive Physiology in Livestock
- Genetic diversity and population structure
- Tree Root and Stability Studies
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Animal Disease Management and Epidemiology
- Animal Genetics and Reproduction
- Cancer, Lipids, and Metabolism
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Identification and Quantification in Food
- Vector-Borne Animal Diseases
- Microbial infections and disease research
- Effects of Environmental Stressors on Livestock
- Wastewater Treatment and Reuse
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Veterinary medicine and infectious diseases
- Poxvirus research and outbreaks
- Veterinary Equine Medical Research
- Lipid metabolism and disorders
- Oral microbiology and periodontitis research
Universidad de Zaragoza
2016-2025
Centro de Investigación en Red en Enfermedades Cardiovasculares
2017-2025
Hospital Universitario Son Espases
2011-2024
Centro de Investigación Biomédica en Red
2022-2024
Hospital Universitario Miguel Servet
1994-2024
Instituto de Investigación Sanitaria Aragón
2014-2024
Clinica de Pneumologie Iaşi
2024
Research Institute Hospital 12 de Octubre
2024
Universidad de Burgos
2022
Health Research Institute of the Balearic Islands
2022
The p.Leu167del mutation in the APOE gene has been associated with hyperlipidemia.Our objective was to determine frequency of subjects autosomal dominant hypercholesterolemia (ADH) whom LDLR, APOB, and PCSK9 mutations had excluded identify mechanisms by which this mutant apo E causes hypercholesterolemia.The analyzed a case-control study.The study conducted at University Hospital Lipid Clinic.Two groups (ADH, 288 patients; control, 220 normolipidemic subjects) were included.We performed...
Limited molecular data exist on the prevalence and subtype distribution of Blastocystis spp., most prevalent parasite in human animal feces worldwide. A total 44 different subtypes (STs) are currently recognized based sequence small subunit ribosomal RNA (SSU-rRNA) gene. This is a study spp. hospitalized patients with gastrointestinal symptoms northern Spain. We analyzed 173 Blastocystis-positive by using nested PCR for detection, identification, phylogenetic analyses, genetic diversity...
Blastocystis sp. is known to be the most prevalent parasite in fecal samples of humans worldwide. In present report, a case–control study (1:9.89 (≈10)) was performed, by analyzing data from 3682 patients who attended public hospital northern area Spain showing gastrointestinal symptoms. Diagnosis performed human means optical microscopy. The prevalence with symptoms 9.18% (338/3682). Most sp.-infected tested negative for protozoa and helminths, were underweight foreign-born (26.4%), mainly...
Lawsonia intracellularis is a Gram-negative, intracellular bacterium that can infect several animal species. In pigs, the bacteria cause porcine proliferative enteropathy, or ileitis. The wide spread of pathogen produces large impact on pig production worldwide. Saliva source biomarkers help to monitor changes in immune system after vaccination. purpose this study was haptoglobin (Hp), immunoglobulin G (IgG), and adenosine deaminase (ADA) saliva vaccination against intracellularis. addition,...
Background The apolipoprotein E (APOE) gene is polymorphic, encoding one of 3 common alleles (ε2, ε3, ε4) produced from combinations 2 non-synonymous SNPs (rs429358 and rs7412). APOE plays an important role controlling plasma lipids but its association with adipocyte functionality body fatness remains to be determined. Methods We analyzed fasting genotyped the two main APOE-SNPs rs7412), both located in fourth exon APOE, 4660 Caucasian middle-aged men free cardiovascular disease. Results...
Methods to reduce castration-related pain in piglets are still issues of concern and interest for authorities producers. Our objectives were estimate the effectiveness two protocols local anesthesia (lidocaine combination lidocaine+bupivacaine) as well use meloxicam a postoperative analgesic alleviating pain, measured by acute physiological responses. Eight groups (15 piglets/group) included study: (1) castration without or analgesia, (TRAD WITHOUT), (2) but with WITH), (3) handling (SHAM...
The majority of hypertriglyceridemias are diagnosed as familial combined hyperlipidemia (FCHL) and primary isolated hypertriglyceridemias. contribution common genetic variants in the difference between FCHL have not been thoroughly examined.This study involved 580 patients with 403 controls. Of 37 single nucleotide polymorphisms examined, 12 located 10 genes showed allelic genotype frequency differences minor alleles APOE, APOA5, GALNTN2, GCKR were positively correlated plasma triglycerides,...
Sow nutrition plays a crucial role impact on fetal and neonates' development, lactation lifetime production of piglets. In this field study, our aim was to evaluate the two feed supplements, namely vitamin C (VC group) combination ferrous sulfate (VC+Fe group), administered during last trimester pregnancy, sow's blood hemoglobin (Hb) concentration individual birth weight The sows came from hyper-prolific genetic lines (Topigs Norsvin Ninety pregnant were randomly divided into three groups:...
Dominant black pigment synthesis in sheep is caused by alterations of the melanocortin‐1 receptor (MC1‐R) coding sequence. Using five bovine microsatellite markers we have mapped MC1‐R gene to chromosome 14, corresponding location other mammalian species. The existence two independent mutations, both causing an amino acid substitution, distantly related breeds sheep, support hypothesis that observed a mutual effect mutations. As similar mutations are found separately at locations dominant...
Coxiella burnetii is an intracellular bacterium causing human Q fever and reproductive disorders in domestic ruminants. We analyzed the occurrence of C. co-infections with six other major pathogens abortion sheep (1242 cases) goat (371 flocks from Spain Portugal. After real-time PCR detection, were established by principal component cluster analysis that grouped cases based on joint presence/absence several microorganisms. Chlamydia abortus most common abortifacient agents approximately 75%...
In order to detect introgression of other Alectoris genus species into wild populations Spanish rufa, we studied a sample 93 red-legged partridges (supposed be A. rufa) captured in the island Majorca. A set 31 chukar (Alectoris chukar) from Cyprus and 33 (A. one farm were also provide suitable for comparison. Factorial correspondence analysis on microsatellite genotypes supported clear distinction birds Cyprus, whereas Majorca overlapped wide area. The existence mitochondrial DNA 16...
Detecting and quantifying the possible association between tegmen tympani (TT) status superior semicircular canal (SSC) pattern.Observational study.Study conducted in three tertiary Spanish hospitals.Nonselected consecutive patients of all ages (607 temporal bones).Thin-section multidetector row computed axial tomography (CAT scan) bones.Thickness SSC bone coverture adjacent to middle fossa, TT as a dichotomous variable: dehiscence (TTD) or integrity (TTI).The observed patterns were (3.79%),...
Natural soil salinization and sodication processes that restrict or prevent crop growth are commonplace in arid regions. In saline‐sodic soils of parts the Canarian archipelago, where annual rainfall is <150 mm, a traditional agriculture system has been developed using basaltic tephra mulch. This enabled dry farming to take place even under most adverse natural conditions. The present work compares salinity‐sodicity cultivated layer were covered with 10 15 cm mulch as recently 20 yr ago...