Charles Quesada

ORCID: 0000-0001-5042-9639
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About
Contact & Profiles
Research Areas
  • Pain Mechanisms and Treatments
  • Transcranial Magnetic Stimulation Studies
  • Pain Management and Treatment
  • Musculoskeletal pain and rehabilitation
  • Functional Brain Connectivity Studies
  • Health, Medicine and Society
  • Advanced Neuroimaging Techniques and Applications
  • Neonatal Health and Biochemistry
  • Neurological disorders and treatments
  • Prenatal Substance Exposure Effects
  • Advanced MRI Techniques and Applications
  • Gestational Diabetes Research and Management
  • Pain Management and Placebo Effect
  • Neuroscience of respiration and sleep
  • Cardiac Arrhythmias and Treatments
  • Trigeminal Neuralgia and Treatments
  • Ion channel regulation and function
  • Healthcare Systems and Practices
  • Cardiovascular Issues in Pregnancy
  • Ion Channels and Receptors
  • Developmental and Educational Neuropsychology
  • Health and Lifestyle Studies
  • Literacy and Educational Practices
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Archaeological and Geological Studies

Université Claude Bernard Lyon 1
2018-2024

Université Jean Monnet
2018-2024

Inserm
2018-2024

Centre de Recherche en Neurosciences de Lyon
2018-2024

Centre National de la Recherche Scientifique
2024

Centre Hospitalier Universitaire de Saint-Étienne
2018-2022

Hospices Civils de Lyon
2021

Centre Hospitalier Le Vinatier
2019

Hôpital Nord
2018

Hospital Universitario De Cabueñes
2003

Repetitive transcranial magnetic stimulation (rTMS) has been proposed to treat neuropathic pain but the quality of evidence remains low. We aimed assess efficacy and safety neuronavigated rTMS primary motor cortex (M1) or dorsolateral prefrontal (DLPFC) in over 25 weeks. carried out a randomized double-blind, placebo-controlled trial at four outpatient clinics France. Patients aged 18-75 years with peripheral were randomly assigned 1:1 ratio M1 DLPFC-rTMS rerandomized 2:1 active sham-rTMS...

10.1093/brain/awab208 article EN Brain 2021-06-01

Abstract Repetitive transcranial magnetic stimulation (rTMS) is a procedure increasingly used to treat patients with central neuropathic pain, but its efficacy still under debate. Patients medically refractory chronic pain were included in 2 randomized phases (active/sham), separated by wash-out period of 8 weeks. Each phase consisted 4 consecutive rTMS sessions and final evaluation session, all from one another 3 High-frequency (20 Hz) was delivered over the primary motor cortex (M1)...

10.1097/j.pain.0000000000001760 article EN Pain 2019-11-20

Abstract Introduction: The ability of repetitive transcranial magnetic stimulation (rTMS) to deliver a field (MF) in deep brain targets is debated and poorly documented. Objective: To quantify the decay MF human brain. Methods: Magnetic was generated by single pulses TMS delivered at maximum intensity using flat or angulated coil. recorded 3D-magnetic probe. Decay measured air both coils head 10 postmortem heads with coil being positioned tangential scalp. interpreted as function distance...

10.1097/pr9.0000000000001134 article EN cc-by-nc-nd PAIN Reports 2024-02-16

This study was undertaken to test whether lesions causing central poststroke pain (CPSP) are associated with a specific connectivity profile, these connections metabolic changes, and this network aligns neuromodulation targets for pain. Two independent lesion datasets were utilized: (1) subcortical from published case reports (2) thalamic imaging using 18F- fluorodeoxyglucose positron emission tomography-computed tomography. Functional between each location the rest of brain assessed...

10.1002/ana.26468 article EN Annals of Neurology 2022-08-03

Abstract Empathetic verbal feedback from others has been shown to alleviate the intensity of experimental pain. To investigate brain changes associated with this effect, we conducted 3T-fMRI measurements in 30 healthy subjects who received painful thermal stimuli on their left hand while overhearing empathetic, neutral or unempathetic comments, supposedly made by experimenters, via headsets. Only empathetic comments significantly reduced pain ratings. A whole-brain BOLD analysis revealed...

10.1038/s41598-019-44879-9 article EN cc-by Scientific Reports 2019-06-10

Selection criteria for offering patients motor cortex stimulation (MCS) refractory neuropathic pain are a critical topic of research. A single session repetitive transcranial magnetic (rTMS) has been advocated selecting MCS candidates, but it low negative predictive value. Here the authors investigated whether multiple rTMS sessions would more accurately predict efficacy.

10.3171/2017.12.jns171333 article EN Journal of neurosurgery 2018-05-18

Current clinical trials indicate that repetitive transcranial magnetic stimulation (rTMS) is effective in reducing drug-resistant neuropathic pain (NP). However, there a lack of studies evaluating the long-term feasibility and efficacy rTMS large patient cohorts real-world conditions.

10.1002/ejp.4763 article EN cc-by European Journal of Pain 2024-12-10
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