A5045356560- Transcranial Magnetic Stimulation Studies
- Pain Management and Treatment
- Pain Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Palliative Care and End-of-Life Issues
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Vestibular and auditory disorders
- Grief, Bereavement, and Mental Health
- Botulinum Toxin and Related Neurological Disorders
- Family Support in Illness
- Patient Dignity and Privacy
- Neurological disorders and treatments
- Spatial Neglect and Hemispheric Dysfunction
- Pain Management and Placebo Effect
- Trigeminal Neuralgia and Treatments
- Sexual function and dysfunction studies
- Attachment and Relationship Dynamics
- Muscle activation and electromyography studies
- Sport Psychology and Performance
- Stroke Rehabilitation and Recovery
- Hallucinations in medical conditions
- Mental Health Research Topics
- Motor Control and Adaptation
- Family and Patient Care in Intensive Care Units
- Nerve injury and regeneration
Hôpital Albert-Chenevier
2019-2024
Assistance Publique – Hôpitaux de Paris
2011-2024
Université Paris-Est Créteil
2016-2024
University of Monastir
2018
Hôpitaux Universitaires Henri-Mondor
2016-2018
Centre Hospitalier Universitaire Henri-Mondor
2015
Inserm
2009-2013
Hôpital Ambroise-Paré
2009-2012
We assessed for the first time long-term maintenance of repetitive transcranial magnetic stimulation (rTMS)-induced analgesia in patients with chronic widespread pain due to fibromyalgia. Forty consecutive were randomly assigned, a double-blind fashion, 2 groups: one receiving active rTMS (n=20) and other, sham (n=20), applied left primary motor cortex. The protocol consisted 14 sessions: an "induction phase" 5 daily sessions followed by "maintenance 3 week apart, fortnight month apart....
Repetitive transcranial magnetic stimulation (rTMS) has been proposed to treat neuropathic pain but the quality of evidence remains low. We aimed assess efficacy and safety neuronavigated rTMS primary motor cortex (M1) or dorsolateral prefrontal (DLPFC) in over 25 weeks. carried out a randomized double-blind, placebo-controlled trial at four outpatient clinics France. Patients aged 18-75 years with peripheral were randomly assigned 1:1 ratio M1 DLPFC-rTMS rerandomized 2:1 active sham-rTMS...
We assessed cortical excitability and intracortical modulation systematically, by transcranial magnetic stimulation (TMS) of the motor cortex, in patients with fibromyalgia. In total 46 female fibromyalgia 21 normal subjects, matched for age, were included this study. TMS was applied to hand area both hemispheres evoked potentials (MEPs) recorded first interosseous muscle contralateral hand. Single-pulse used measurements rest threshold (RMT) suprathreshold MEP. Paired-pulse assess short...
We investigated the role of endogenous opioid systems in analgesic effects induced by repetitive transcranial magnetic stimulation (rTMS). compared motor cortex (M1) or dorsolateral prefrontal (DLPFC) before and after naloxone placebo treatment, a randomized, double-blind crossover design, healthy volunteers. Three groups 12 volunteers were selected at random given active (frequency 10Hz, 80% threshold intensity, 1500 pulses per session) right M1, DLPFC, sham stimulation, during two...
No study has directly compared the effectiveness of repetitive transcranial magnetic stimulation (rTMS) and direct-current (tDCS) in neuropathic pain (NP). In this 2-centre randomised double-blind sham-controlled study, we efficacy 10-Hz rTMS anodal 2-mA tDCS motor cortex sham contralateral to painful area (3 daily sessions) patients with NP due lumbosacral radiculopathy. Average intensity (primary outcome) was evaluated after each session 5 days later. Secondary outcomes included symptoms...
We investigated the analgesic effects of unilateral repetitive transcranial magnetic stimulation (rTMS) motor cortex (M1) or dorsolateral prefrontal (DLPFC) in two models experimental pain healthy volunteers. Two studies were carried out parallel groups 26 paid The active sham rTMS (frequency, 10Hz; intensity, 80% resting threshold) applied to right M1 DLPFC compared a double-blind randomized cross-over design. In first series experiments, we analyzed on thermal (heat and cold) detection...
We investigated the role of glutamate N-methyl-d-aspartate (NMDA) receptors in analgesic effects induced by repetitive transcranial magnetic stimulation (rTMS). In a randomized, double-blind, crossover study, we compared ketamine and placebo on motor cortex (M1) or dorsolateral prefrontal cortex/premotor (DLPFC/PMC) stimulation. Three groups 12 healthy volunteers underwent active rTMS (10Hz, 80% resting threshold, 1,500 pulses per session) right M1, DLPFC/PMC, sham during 2 experimental...
Abstract Background Pain is a common symptom in palliative care cancer patients and often insufficiently relieved. In recent years, transcranial direct-current stimulation (tDCS) of the motor cortex has been shown to be effective treat chronic pain, essentially neuropathic pain. We propose test efficacy tDCS experiencing pain setting. Method/design This article describes protocol bicentre, randomized, parallel-arm, sham-controlled clinical trial evaluating treatment with refractory Seventy...
Abstract Objectives Psychological consequences of grief among relatives are insufficiently known. We reported incidence prolonged deceased patients with cancer. Methods Prospective cohort study 611 531 cancer hospitalized for more than 72 hours and who died in 26 palliative care units was conducted. The primary outcome 6 months after patient death, measured the Inventory Complicated Grief (ICG > 25, range 0–76, a higher score indicates severe symptoms) score. Secondary outcomes death were...
Abstract Background Grieving relatives can suffer from numerous consequences like anxiety, depression, post-traumatic stress disorder (PTSD) symptoms, and prolonged grief. This study aims to assess the psychological of grieving after patients’ death in French palliative care units their needs for support. Methods is a prospective observational multicenter mixed study. Relatives adult patients with neoplasia expected be hospitalized more than 72 h unit end-of-life issues will included within...
Abstract Background Prolonged grief is a chronic and debilitating condition that affects millions of persons worldwide. The aim this study was to use qualitative approach better understand how relatives with prolonged disorder perceive what does or not help them whether they were able make recommendations. Methods Participants all deceased patients admitted 26 palliative care units involved in the FamiLife study; included if diagnosed symptoms (i.e., Inventory Complicated Grief (ICG)...