- Pain Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Botulinum Toxin and Related Neurological Disorders
- Pain Management and Treatment
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Pain Management and Placebo Effect
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Genetic Neurodegenerative Diseases
- Pain Management and Opioid Use
- Pediatric Pain Management Techniques
- Nerve Injury and Rehabilitation
- Anesthesia and Pain Management
- Myofascial pain diagnosis and treatment
- Advanced Neuroimaging Techniques and Applications
- Cancer Treatment and Pharmacology
- Migraine and Headache Studies
- Stroke Rehabilitation and Recovery
- Trigeminal Neuralgia and Treatments
- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Vestibular and auditory disorders
- Heart Rate Variability and Autonomic Control
- Peripheral Nerve Disorders
Aalborg University
2022-2025
Universidade de São Paulo
2016-2025
Universidade Federal de São Paulo
2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2013-2024
Hospital Universitário da Universidade de São Paulo
2007-2024
Hospital São Paulo
2013-2024
Massachusetts General Hospital
2024
Universidade Federal de Pernambuco
2024
Instituto de Telecomunicações
2023
University of Aveiro
2023
We assessed for the first time long-term maintenance of repetitive transcranial magnetic stimulation (rTMS)-induced analgesia in patients with chronic widespread pain due to fibromyalgia. Forty consecutive were randomly assigned, a double-blind fashion, 2 groups: one receiving active rTMS (n=20) and other, sham (n=20), applied left primary motor cortex. The protocol consisted 14 sessions: an "induction phase" 5 daily sessions followed by "maintenance 3 week apart, fortnight month apart....
We assessed cortical excitability and intracortical modulation systematically, by transcranial magnetic stimulation (TMS) of the motor cortex, in patients with fibromyalgia. In total 46 female fibromyalgia 21 normal subjects, matched for age, were included this study. TMS was applied to hand area both hemispheres evoked potentials (MEPs) recorded first interosseous muscle contralateral hand. Single-pulse used measurements rest threshold (RMT) suprathreshold MEP. Paired-pulse assess short...
We investigated the role of endogenous opioid systems in analgesic effects induced by repetitive transcranial magnetic stimulation (rTMS). compared motor cortex (M1) or dorsolateral prefrontal (DLPFC) before and after naloxone placebo treatment, a randomized, double-blind crossover design, healthy volunteers. Three groups 12 volunteers were selected at random given active (frequency 10Hz, 80% threshold intensity, 1500 pulses per session) right M1, DLPFC, sham stimulation, during two...
Transcranial magnetic stimulation (TMS) is a noninvasive brain technique with potential to improve memory. Mild cognitive impairment (MCI), which still lacks specific therapy, clinical syndrome associated increased risk of dementia. This study aims assess the effects high-frequency repetitive TMS (HF rTMS) on everyday memory elderly MCI. We conducted double-blinded randomized sham-controlled trial using rTMS over left dorsolateral prefrontal cortex (DLPFC). Thirty-four outpatients meeting...
To prospectively evaluate the effect of subthalamic nucleus deep brain stimulation (STN-DBS) on different characteristics pain and other nonmotor symptoms (NMS) in patients with Parkinson disease (PD).Forty-four PD refractory motor were screened for STN-DBS. Patients evaluated before 1 year after surgery. The primary outcome was change prevalence Secondary measures changes function (Unified Parkinson's Disease Rating Scale), NMS using specific scales questionnaires, quality life.Forty-one...
'Conventional' protocols of high-frequency repetitive transcranial magnetic stimulation (rTMS) delivered to M1 can produce analgesia. Theta burst (TBS), a novel rTMS paradigm, is thought greater changes in excitability than 'conventional' protocols. After preliminary experiment showing no analgesic effect continuous or intermittent TBS trains (cTBS iTBS) as single procedures, we used prime subsequent session 10 Hz-rTMS.In 14 patients with chronic refractory neuropathic pain, navigated was...
<h3>Objective</h3> To compare the analgesic effects of stimulation anterior cingulate cortex (ACC) or posterior superior insula (PSI) against sham deep (d) repetitive (r) transcranial magnetic (TMS) in patients with central neuropathic pain (CNP) after stroke spinal cord injury a randomized, double-blinded, sham-controlled, 3-arm parallel study. <h3>Methods</h3> Participants were randomly allocated into active PSI-rTMS, ACC-rTMS, sham-PSI-rTMS, sham-ACC-rTMS arms. Stimulations performed for...
No study has directly compared the effectiveness of repetitive transcranial magnetic stimulation (rTMS) and direct-current (tDCS) in neuropathic pain (NP). In this 2-centre randomised double-blind sham-controlled study, we efficacy 10-Hz rTMS anodal 2-mA tDCS motor cortex sham contralateral to painful area (3 daily sessions) patients with NP due lumbosacral radiculopathy. Average intensity (primary outcome) was evaluated after each session 5 days later. Secondary outcomes included symptoms...
Abstract Background We assessed whether COVID‐19 is associated with de novo pain and chronic (CP). Methods This controlled cross‐sectional study was based on phone interviews of patients discharged from hospital after compared to the control group composed individuals hospitalized during same period due non‐COVID‐19 causes. Patients were classified as having previous CP ICD‐11/IASP criteria, (i.e. any new type pain, irrespective status before stay), persistent or recurring lasting more than...