- Transcranial Magnetic Stimulation Studies
- Pain Mechanisms and Treatments
- Pain Management and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Musculoskeletal pain and rehabilitation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Long-Term Effects of COVID-19
- Neurological disorders and treatments
- Pain Management and Placebo Effect
- Health, Nursing, Elderly Care
- Stroke Rehabilitation and Recovery
- Infant Development and Preterm Care
- Anesthesia and Pain Management
- Optical Imaging and Spectroscopy Techniques
- Pediatric Pain Management Techniques
- Heart Rate Variability and Autonomic Control
- Vagus Nerve Stimulation Research
- Functional Brain Connectivity Studies
- Muscle activation and electromyography studies
- Balance, Gait, and Falls Prevention
- Physical Education and Gymnastics
- Healthcare during COVID-19 Pandemic
- Pelvic floor disorders treatments
- Anatomy and Medical Technology
- Health Education and Validation
Universidade de São Paulo
2019-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2020-2021
Hospital Universitário da Universidade de São Paulo
2020-2021
Instituto do Câncer do Estado de São Paulo
2019
Universidade Federal da Paraíba
2012-2018
<h3>Objective</h3> To compare the analgesic effects of stimulation anterior cingulate cortex (ACC) or posterior superior insula (PSI) against sham deep (d) repetitive (r) transcranial magnetic (TMS) in patients with central neuropathic pain (CNP) after stroke spinal cord injury a randomized, double-blinded, sham-controlled, 3-arm parallel study. <h3>Methods</h3> Participants were randomly allocated into active PSI-rTMS, ACC-rTMS, sham-PSI-rTMS, sham-ACC-rTMS arms. Stimulations performed for...
Abstract Background We assessed whether COVID‐19 is associated with de novo pain and chronic (CP). Methods This controlled cross‐sectional study was based on phone interviews of patients discharged from hospital after compared to the control group composed individuals hospitalized during same period due non‐COVID‐19 causes. Patients were classified as having previous CP ICD‐11/IASP criteria, (i.e. any new type pain, irrespective status before stay), persistent or recurring lasting more than...
Pain is a common nonmotor symptom in patients with Parkinson disease (PD) but the correct diagnosis of respective cause remains difficult because suitable tools are lacking, so far. We developed framework to differentiate PD- from non-PD-related pain and classify PD-related into 3 groups based on validated mechanistic descriptors (nociceptive, neuropathic, or nociplastic), which encompass all previously described PD types. Severity syndromes was scored by ratings intensity, frequency,...
Abstract The personalization of neuropathic pain treatment could be improved by identifying specific sensory phenotypes (ie, combinations symptoms and signs) predictive the response to different classes drugs. A simple reliable phenotyping method is required for such a strategy. We investigated utility an algorithm stratifying patients into clusters corresponding assessed with Neuropathic Pain Symptom Inventory (NPSI). Consistent previous results, we first confirmed, in cohort 628 patients,...
Despite affecting 2-4% of the population worldwide, fibromyalgia often remains refractory to treatment. Here we report first international randomised double-blind, sham-controlled trial developed assess efficacy repetitive transcranial magnetic stimulation (rTMS) as an add-on therapy for fibromyalgia. Women aged ≥18 yr with best available treatment were enrolled in Brazil, France, and Japan, 10 Hz motor cortex (M1) rTMS, 3000 pulses day-1, or sham stimulation. This included induction...
Abstract Background Dystonia is associated with disabling nonmotor symptoms like chronic pain (CP), which prevalent in dystonia and significantly impacts the quality of life (QoL). There no validated tool for assessing CP dystonia, substantially hampers management. Objective The aim was to develop a classification scoring system dystonia. Methods A multidisciplinary group established Dystonia‐Pain Classification System (Dystonia‐PCS). as related or unrelated followed by assessment severity...
INTRODUÇÃO: A população idosa apresenta-se em um acelerado processo de crescimento associado ao aumento da expectativa vida. As alterações no envelhecimento podem comprometer o padrão marcha e equilíbrio dos idosos, predispondo-os a quedas. Como estratégia prevenção, indica-se atividade física regular direcionada para ganho força, equilíbrio, propriocepção melhoria marcha. OBJETIVO: Verificar os efeitos programa exercícios físicos na mobilidade funcional idosos. MATERIAIS E MÉTODOS:...
The question of whether the human fetus experiences pain has received substantial attention in recent times. With advent high-definition 4-dimensional ultrasound (4D-US), it is possible to record fetal body and facial expressions.To determine fetuses demonstrate discriminative acute behavioral responses nociceptive input.This cross-sectional study included 5 with diaphragmatic hernia indication intrauterine surgery (fetoscopic endoluminal tracheal occlusion) 8 healthy fetuses, who were...
In this randomized, double-blind, parallel placebo-controlled clinical trial, we evaluated the efficacy of methadone as an add-on therapy for people with chronic neuropathic pain (NP). Eighty-six patients were randomly assigned to receive or placebo 8 weeks. The primary outcome was proportion participants achieving at least 30% relief from baseline using a 100-mm Visual Analogue Scale. Secondary outcomes included global impression change, NP symptoms, sleep quality, quality life,...
Background: Novel coronavirus disease (COVID-19) is not restricted to the respiratory system, but also affects peripheral (PNS) and central (CNS) nervous systems which appear influence morbidity mortality. It urgent approach all aspects of in order attenuate impact pandemic. Noninvasive neuromodulation (NiN) might be useful management disorders related infection, considering its efficacy modulation inflammation, neuroimmunity, musculoskeletal symptoms, neuropsychiatric associated with...
It is not known whether cortical plastic changes reported in low-back pain (LBP) are present all etiologies of LBP. Here we report on the assessment patients with three LBP conditions: non-specific-LBP (ns-LBP), failed back surgery syndrome (FBSS), and sciatica (Sc).Patients underwent a standardized clinical pain, conditioned modulation (CPM), measures motor evoked potential (MEPs)-based corticospinal excitability (CE) by transcranial magnetic stimulation, including short interval...
INTRODUCTION: Despite being considered least important for clinical practice in the pyramid of evidence recommendations, sometimes scientists' expert opinions could help to better understand summarization updated publications. OBJECTIVE: To provide a major summarized update about brain imaging and stimulation nervous system health disease. METHODS: Comprehensive review developed by experts each subarea knowledge neuroimaging non-invasive system. A team researchers clinic was invited present...
BACKGROUND: The posterior-superior insula (PSI) has emerged as a potential target for non-invasive brain stimulation (NIBS) in the treatment of peripheral neuropathic pain. However, current methods identifying PSI require expensive and time-consuming imaging neuronavigation. Here, we propose Fast-PSI method, novel approach based on craniometry intracranial Euclidean distances proportions comparisons between scalp landmarks, to swiftly accurately locate projection scalp. METHODS: Eleven...