- Transcranial Magnetic Stimulation Studies
- Stroke Rehabilitation and Recovery
- Muscle activation and electromyography studies
- Pain Management and Treatment
- Neurological disorders and treatments
- Vestibular and auditory disorders
- Neuroscience and Neural Engineering
- Botulinum Toxin and Related Neurological Disorders
- Musculoskeletal pain and rehabilitation
- EEG and Brain-Computer Interfaces
- Cerebral Palsy and Movement Disorders
- Migraine and Headache Studies
- Myofascial pain diagnosis and treatment
- Pain Mechanisms and Treatments
- Motor Control and Adaptation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Hemispheric Asymmetry in Neuroscience
- Neural and Behavioral Psychology Studies
- Long-Term Effects of COVID-19
- Spinal Cord Injury Research
- Obsessive-Compulsive Spectrum Disorders
- Optical Imaging and Spectroscopy Techniques
- Laser Applications in Dentistry and Medicine
- Health Education and Validation
- Parkinson's Disease Mechanisms and Treatments
Universidade Federal de Pernambuco
2016-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2025
National Education and Research Network
2020
Centre for Interdisciplinary Research in Rehabilitation
2019
Jewish Rehabilitation Hospital
2019
Foundation for Physical Medicine and Rehabilitation
2018
Universidade Federal da Paraíba
2016
University of Göttingen
2009-2016
TU Dortmund University
2016
Leibniz Research Centre for Working Environment and Human Factors
2016
Transcranial DC stimulation (tDCS) is a plasticity-inducing noninvasive brain tool with various potential therapeutic applications in neurological and psychiatric diseases. Currently, the duration of aftereffects restricted. For future clinical applications, protocols are required that produce lasting for days or weeks. Options to prolong effects tDCS further prolongation repetition tDCS. Nothing known thus far about optimal this behalf, although repetitive already performed applications....
The neuromodulator dopamine (DA) has multiple modes of action on neuroplasticity induction and modulation, depending subreceptor specificity, concentration level, the kind stimulation-induced plasticity. To determine dosage-dependent effects D 2 -like receptor activation nonfocal focal in human motor cortex, different doses ropinirole (0.125, 0.25, 0.5, 1.0 mg), a /D 3 agonist, or placebo medication were combined with anodal cathodal transcranial direct current stimulation (tDCS) protocols,...
The neuromodulator dopamine affects learning and memory formation their likely physiological correlates, long-term depression potentiation, in animals humans. It is known from animal experiments that exerts a dosage-dependent, inverted U-shaped effect on these functions. However, this has not been explored humans so far. In order to reveal non-linear dose-dependent of cortical plasticity humans, we the impact 25, 100 200 mg L-dopa transcranial direct current (tDCS)-induced twelve healthy...
Background: Upper limb (UL) impairment is the most common disabling deficit following a stroke. Previous studies have suggested that transcranial direct current stimulation (tDCS) enhances effect of conventional therapies. Objective: This pilot d
Purpose: This pilot double-blind sham-controlled randomized trial aimed to determine if the addition of anodal tDCS on affected hemisphere or cathodal unaffected modified constraint-induced movement therapy (mCIMT) would be superior constraints alone in improving upper limb function chronic stroke patients. Methods: Twenty-one patients with were randomly assigned receive 12 sessions either (i) anodal, (ii) (iii) sham combined mCIMT. Fugl–Meyer assessment (FMA), motor activity log scale...
Dopamine improves learning and memory formation. The neurophysiological basis for these effects might be a focusing effect of dopamine on neuroplasticity: Accordingly, in humans l -dopa prolongs focal facilitatory plasticity, but turns nonfocal plasticity into inhibition. Here we explore the impact D 1 receptors plasticity. Nonfocal was induced by transcranial direct current stimulation (tDCS), paired associative (PAS). Subjects received sulpiride, 2 antagonist, to increase relative...
Objective: The aim of this study is to investigate the effects transcranial direct current stimulation (tDCS) combined with cueing gait training (CGT) on functional mobility in patients Parkinson´s disease (PD). Methods: A pilot double-blind controlled, randomized clinical trial was conducted 22 PD assigned experimental (anodal tDCS plus CGT) and control group (sham CGT). primary outcome (functional mobility) assessed by 10-m walk test, cadence, stride length, Timed Up Go test. Motor...
We investigated the effects of brain-computer interface (BCI) combined with mental practice (MP) and occupational therapy (OT) on performance in activities daily living (ADL) stroke survivors.Participants were randomized into two groups: experimental (n = 23, BCI controlling a hand exoskeleton MP OT) control 21, OT). Subjects assessed functional independence measure (FIM), motor activity log (MAL), amount use (MAL-AOM), quality movement (MAL-QOM). The box blocks test (BBT) Jebsen (JHFT) used...
Mental practice can induce significant neural plasticity and result in motor performance improvement if associated with imagery tasks. Given the effects of transcranial direct current stimulation (tDCS) on neuroplasticity, study tested whether tDCS, using different electrode montages, increase neuroplastic mental learning. Eighteen healthy right-handed adults underwent a randomised sham-controlled crossover experiment to receive training combined either sham or active anodal tDCS right...
Noninvasive brain stimulation has recently been used to augment motor training-induced plasticity. However, the exact time during which noninvasive can be combined with therapy maximize neuroplasticity and behavioral changes is unknown. We conducted a randomized sham-controlled crossover trial examine when (before, during, or after training) transcranial direct current (tDCS) should applied best reinforce plasticity in 12 healthy right-handed participants (mean age: 21.8±1.6) who underwent...
Abstract Background Approximately 80% of individuals with chronic stroke present long lasting upper extremity (UE) impairments. We designed the perSonalized UPper Extremity Rehabilitation (SUPER) intervention, which combines robotics, virtual reality activities, and neuromuscular electrical stimulation (NMES). The objectives our study were to determine feasibility preliminary efficacy SUPER intervention in moderate/severe stroke. Methods Stroke participants (n = 28) received a 4-week (3 ×...
Background A better understanding of migraine pathophysiology through standardized methods could facilitate the development more effective therapeutic approaches for sufferers. However, neurophysiological studies with sufferers present larger variability, as most contain only a single measurement. Objective This observational study aimed to compare cortical and visual excitability sufferers, individuals other types headaches, healthy participants in response pattern-reversal stimulation....
Despite affecting 2-4% of the population worldwide, fibromyalgia often remains refractory to treatment. Here we report first international randomised double-blind, sham-controlled trial developed assess efficacy repetitive transcranial magnetic stimulation (rTMS) as an add-on therapy for fibromyalgia. Women aged ≥18 yr with best available treatment were enrolled in Brazil, France, and Japan, 10 Hz motor cortex (M1) rTMS, 3000 pulses day-1, or sham stimulation. This included induction...
Chronic exposure to nicotine is related low activity in the prefrontal cortex and insular hyperactivity smokers. Therefore, addiction has been target of experimental studies aerobic exercise (AE) transcranial direct current stimulation (tDCS). Thus, objective this study was verify effect AE anodal tDCS at F4 cathodal T3 on craving, motivation change smoking behaviour (MCSB) brain reactivity (BR) The sample consisted 41 chronic smokers distributed into four groups: (G1), (G2), combined with...