- Motor Control and Adaptation
- Balance, Gait, and Falls Prevention
- Action Observation and Synchronization
- Transcranial Magnetic Stimulation Studies
- Long-Term Effects of COVID-19
- Muscle activation and electromyography studies
- Cerebral Palsy and Movement Disorders
- Sport Psychology and Performance
- Stroke Rehabilitation and Recovery
- Genetic Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- Tactile and Sensory Interactions
- Heart Rate Variability and Autonomic Control
- EEG and Brain-Computer Interfaces
- Orthopedic Surgery and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Advanced Neuroimaging Techniques and Applications
- Parkinson's Disease Mechanisms and Treatments
- Functional Brain Connectivity Studies
- COVID-19 Clinical Research Studies
- Neural and Behavioral Psychology Studies
- Musculoskeletal pain and rehabilitation
- Foot and Ankle Surgery
- Visual perception and processing mechanisms
- Physical Education and Gymnastics
D’Or Institute for Research and Education
2014-2024
Universidad Europea del Atlántico
2024
Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2024
Stockholm South General Hospital
2024
Karolinska Institutet
2024
Hospital Civil de Guadalajara
2024
Karolinska University Hospital
2024
San Antonio College
2024
Instituto de Saúde
2024
Fundação de Amparo à Pesquisa do Estado do Amazonas
2024
Abstract Postural sway and heart rate were recorded in young men viewing emotionally engaging pictures. It was hypothesized that they would show a human analog of “freezing” behavior (i.e., immobility deceleration) when confronted with sustained block unpleasant (mutilation) images, relative to their response pleasant/arousing (sport action) or neutral (objects) Volunteers stood on stabilometric platform during picture viewing. Significantly reduced body the pictures, along increased mean...
Previous studies have indicated that amputation or deafferentation of a limb induces functional changes in sensory (S1) and motor (M1) cortices, related to phantom pain. However, the extent cortical reorganization after lower patients with nonpainful phenomena remains uncertain. In this study, we combined magnetic resonance (fMRI) diffusion tensor imaging (DTI) investigate existence callosal plasticity these subjects. Nine "painless" nine control subjects (sex- age-matched) underwent 3-T MRI...
Significance Individuals subjected to surgical transection of the corpus callosum (“split-brains”) fail transfer information between cerebral hemispheres, a condition known as “disconnection syndrome.” On other hand, subjects born without (callosal dysgenesis, CD) typically show preserved interhemispheric communication. To clarify this paradox, which has defied neuroscientists for decades, we investigated CD using functional and structural neuroimaging neuropsychological tests. Results...
Neurofeedback by functional magnetic resonance imaging (fMRI) is a technique of potential therapeutic relevance that allows individuals to be aware their own neurophysiological responses and voluntarily modulate the activity specific brain regions, such as premotor cortex (PMC), important for motor recovery after injury. We investigated (i) whether healthy human volunteers are able up-regulate left PMC during right hand finger tapping imagery (MI) task while receiving continuous...
COVID-19 has become a dramatic health problem during this century. In addition to high mortality rate, survivors are at increased risk for cardiovascular diseases 1-year after infection. Explanations these manifestations still unclear but can involve constellation of biological alterations. We hypothesized that compared with controls exhibit sympathetic overdrive, vascular dysfunction, cardiac morpho-functional changes, impaired exercise capacity, and oxidative stress.Nineteen severe 19...
The purpose of this study was to investigate the correlation between body adiposity and postural control in elderly women.
O objetivo do estudo foi comparar os níveis de condicionamento físico (resistência aeróbica, força e flexibilidade) em idosas ativas (N=55) da Casa Idoso na Cidade Belém-PA, Brasil.Também participaram desta pesquisa 10 sedentárias, voluntárias, que pertencem à comunidade ao redor casa idoso foram divididas quatro grupos: musculação (GMusc: n=20; idade=67.2±5.66 anos; IMC=26.77±4.53 kg/m2); dança (GDan: idade=68.5±3.47 IMC=26.53±2.91 kg/m2), meditação (GMed: n=15; idade=68.1±4.37...
Esta pesquisa objetivou comparar os níveis de autonomia funcional, atividade física, qualidade vida, depressão, IGF1 e resistência aeróbica entre idosas sedentárias ativas. Para este estudo ex post facto, a amostra foi dividida em quatro grupos: grupo dança (GD, n=10; idade=72,50±5,10 anos); musculação (GF, idade=69,80±3,94 meditação (GM, idade=68,80±4,39 anos) controle (GC, idade=73,40±7,49 anos). Os protocolos utilizados nas avaliações foram: bateria testes do Grupo Desenvolvimento...
The human primary motor cortex (M1) undergoes considerable reorganization in response to traumatic upper limb amputation. representations of the preserved arm muscles expand, invading portions M1 previously dedicated hand, suggesting that former hand neurons are reassigned control remaining proximal muscles. Hand allograft offers a unique opportunity study reversibility such long-term cortical changes. We used transcranial magnetic stimulation patient LB, who underwent bilateral...
Background The success of pancreatic islet transplantation still faces many challenges, mainly related to cell damage during isolation and early post-transplant. increased generation reactive oxygen species (ROS) the consumption antioxidant defenses appear be an important pathway damage. Methodology/Principal Findings In present study we evaluated whether supplementation glutathione-ethyl-ester (GEE) could improve viability transplant outcomes in a murine marginal mass model. We also...
Amputation in adults is associated with an extensive remapping of cortical topography primary and secondary sensorimotor areas. Here, we used tactile residual limb stimulation 3T functional magnetic resonance imaging humans to investigate connectivity changes the network patients long-term lower traumatic amputations phantom sensation, but without pain. We found a pronounced reduction inter-hemispheric between homologous regions amputees, including (S1) (S2) somatosensory areas, (M1) (M2)...
COVID-19 induces acute and persistent neurological symptoms in mild severe cases. Proposed concomitant mechanisms include direct viral infection strain, coagulopathy, hypoxia, neuroinflammation. However, underlying molecular alterations associated with multiple outcomes both cases are majorly unexplored. To illuminate possible leading to disease, we retrospectively investigated detail a cohort of 35 hospitalized patients presenting subject clinically indicated cerebrospinal fluid (CSF)...
Evolutionary theories posit that emotions prime organisms for action. This study examined whether corticospinal excitability (CSE) is modulated by the emotional valence of a to-be-grasped stimulus. CSE was estimated based on amplitude motor evoked potentials (MEPs) elicited using transcranial magnetic stimulation (TMS) and recorded first dorsal interosseous (FDI) muscle. Participants were instructed to grasp (ACTION condition) or just look at (NO-ACTION unpleasant, pleasant neutral stimuli....
<b>Background and Objective</b> Supplementary motor area (SMA) syndrome, an executive disorder with speech dysfunctions, is rather unpredictable typically a complete or almost functional recovery within weeks months. Compensatory mechanisms are associated contralateral cortical recruitment of the lateral premotor circuitry. We sought to investigate role healthy SMA for following surgery in medial frontal lobe. <b>Methods</b> A 48-year-old right-handed man presented focal seizures. The...
Abstract The basic underpinnings of homeostatic behavior include interacting with positive items and avoiding negative ones. As the planning aspects goal-directed actions can be inferred from their movement features, we investigated kinematics emotion-laden stimuli. Participants were instructed to grasp stimuli bring them toward bodies while wrist was measured. results showed that time peak velocity increased for bringing pleasant towards body compared unpleasant neutral ones, suggesting...
A ataxia espinocerebelar (SCA) é uma afecção hereditária que cursa com a degeneração progressiva do cerebelo e suas vias, causando alterações equilíbrio de outras funções. O efeito das abordagens da fisioterapia no tratamento SCA qualidade metodológica desses estudos foram analisados. Foi investigado ainda se os benefícios alcançados o são retidos. As intervenções encontradas incluem treino equilíbrio, marcha coordenação; fortalecimento; caneleiras nos membros durante exercícios aplicação...
Contemporary theories of motor control propose that planning involves the prediction consequences actions. These predictions include associated costs as well rewarding nature movements' outcomes. Within estimation these and rewards would lie valence, is, pleasantness or unpleasantness a given stimulus with which one is about to interact. The aim this study was test if preparation encompasses valence.The readiness potential, an electrophysiological marker preparation, recorded before grasping...
Abstract Cross‐modal plasticity in blind individuals has been reported over the past decades showing that nonvisual information is carried and processed by “visual” brain structures. However, despite multiple efforts, structural underpinnings of cross‐modal congenitally remain unclear. We mapped thalamocortical connectivity assessed integrity white matter 10 sighted controls. hypothesized an aberrant pattern taking place absence visual stimuli from birth as a potential mechanism plasticity....