A5026599908- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Retinal Development and Disorders
- Neuroscience and Neural Engineering
- Blind Source Separation Techniques
- Photoreceptor and optogenetics research
- Vestibular and auditory disorders
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
- Neuroscience and Music Perception
- Advanced Adaptive Filtering Techniques
- Meningioma and schwannoma management
- Cardiac Arrhythmias and Treatments
- Spinal Cord Injury Research
- Muscle activation and electromyography studies
- Cardiac electrophysiology and arrhythmias
- Visual perception and processing mechanisms
- Speech and Audio Processing
- Biomedical and Engineering Education
- Advanced Memory and Neural Computing
- Cerebral Venous Sinus Thrombosis
- Engineering Education and Pedagogy
- Semiconductor Quantum Structures and Devices
University of Miami
2015-2024
Jackson Memorial Hospital
2023
Northwestern University
2023
Universidad de Los Andes
1988-2014
Centre de Recherche en Neurosciences de Lyon
1992-1997
Inserm
1992-1997
Institut National de Recherche en Santé Publique
1990
Presents a method to analyze and filter digital signals of finite duration by means time-frequency representation. This is done defining purely invertible discrete transform, representing signal either in the time or domain, as simply possible with conventional Fourier transform between frequency domains. The wavelet concept has been used build this transform. To get correct invertibility procedure, authors have proposed orthogonal periodic basic wavelets. properties such are described,...
We recorded pattern electroretinograms (PERGs) simultaneously from each eye in mice using binocular stimulation and a common noncorneal electrode.The PERG was derived 71 ketamine/xylazine anesthetized (C57BL/6J, 4 months old) subcutaneous needles (active, snout; reference, back of the head; ground, root tail) response to contrast-reversal gratings (0.05 cycles/deg, >95% contrast) generated on two custom-made light-emitting diode (LED) tablets alternating at slight different frequencies (OD,...
Abstract Objectives/Hypothesis: To investigate the molecular mechanisms involved in electrode insertion trauma (EIT) and to test otoprotective effect of locally delivered AM‐111. Study Design: An animal model cochlear implantation. Methods: Guinea pigs' hearing thresholds were measured by auditory brainstem response (ABR) before after implantation four groups: EIT; pretreated with hyaluronate gel 30 minutes EIT (EIT+Gel); gel/AM‐111 (EIT+AM‐111); unoperated contralateral ears as controls....
To prospectively evaluate the association between hearing preservation after cochlear implantation (CI) and intracochlear electrocochleography (ECochG) amplitude parameters.
In this study, a frequency domain formulation of continuous loop averaging deconvolution (CLAD) overlapping evoked potentials is developed and applied for the extraction transient responses from recordings obtained at high stimulation rates. This allows faster execution CLAD by using fast Fourier transform algorithms. The characteristics filter depends exclusively on stimulus sequence determines whether noncoherent noise amplified or attenuated in different frequencies. A formula calculating...
To investigate the use of transtympanic electrocochleography (TT-ECochG) analyzed on-line by a detector strategy software that made possible automatic extraction TT-ECochG components intraoperatively in real-time domain.Fifteen patients with cerebellopontine angle tumor among 50 were included this study.All subjects operated on via middle fossa or retrosigmoid approach. Pure-tone average (PTA) was measured at 0.5, 1.0, and 2.0 kHz, calculations performed before after surgery. Auditory...
ABSTRACT Mesenchymal stem cell (MSC) therapy is an emerging treatment modality for various human diseases. Although induced pluripotent cells have been explored the restoration of hearing, potential MSCs as a therapeutic strategy cochlear insults not precisely known. possess anti‐inflammatory, anti‐apoptotic and neuroprotective properties, making them attractive target inner ear disorders such hair damage in response to inflammation. Most previous studies used immunosuppression or complex...
Cutaneous reflexes were tested to examine the neuronal mechanisms contributing muscle spasms in humans with chronic spinal cord injury (SCI). Specifically, we effect of Achilles and tibialis anterior tendon vibration on early late components cutaneous reflex reciprocal Ia inhibition soleus muscles SCI. We found that reduced amplitude later but not earlier antagonist agonist relative location vibration. In addition, between ankle increased participants a larger suppression component had...
Objectives To evaluate the utility of intracochlear electrocochleography (ECochG) monitoring during cochlear implant (CI) surgery on postoperative hearing preservation. Study Design Prospective, randomized clinical trial. Setting Ten high-volume, tertiary care CI centers. Patients Adult patients with sensorineural loss meeting criteria who selected an Advanced Bionics CI. Methods were to either audible ECochG available surgeon electrode insertion or without monitoring. Hearing preservation...
In this study a general formula for the signal to noise ratio (SNR) of maximum length sequence (MLS) deconvolution averaging is developed using frequency domain framework generalized continuous loop procedure [Özdamar and Bohórquez, J. Acoust. Soc. Am. 119, 429–438 (2006)]. This formulation takes advantage well known equivalency energies in time domains (Parseval's theorem) show that MLS deconvolution, SNR increases with square root half number stimuli sweep. increase less than conventional...
(2011). Local drug delivery to conserve hearing: mechanisms of action eluted dexamethasone within the cochlea. Cochlear Implants International: Vol. 12, Proceedings 11th International Conference on and Other Implantable Auditory Technologies, pp. S51-S53.
To compare a new method for steady-state pattern electroretinogram (PERGx) with validated (PERGLA) in normal controls and patients optic neuropathy.PERGx PERGLA were recorded mixed population (n = 33, 66 eyes) of younger (C1; n 10, age 38 ± 8.3 years), older (C2; 11, 57.9 8.09 early manifest glaucoma (G; 7, 65.7 ±11.6 nonarteritic ischemic neuropathy (N; 5, mean 59.4 8.6 years). The PERGx stimulus was black-white horizontal grating generated on 14 × cm LED display (1.6 cycles/deg, 15.63...
Background The auditory middle-latency response (transient) and the 40-Hz steady state (ASSR) are modulated by anesthetics. However, quantitative relation between these evoked responses is difficult to obtain because of technical limitations recording methods used transients at high stimulation rates. This study uses continuous-loop averaging deconvolution fill this gap transient ASSR waveform during general anesthesia. Methods authors recorded 5- ASSRs in 13 subjects were predict linearly...
Electrophysiological indices of auditory binaural beats illusions are studied using late latency evoked responses. Binaural generated by continuous monaural FM tones with slightly different ascending and descending frequencies lasting about 25 ms presented at 1 sec intervals. Frequency changes carefully adjusted to avoid any creation abrupt waveform changes. Interaction Component (BIC) analysis is used separate the neural responses due involvement. The results show that transient can be...