Nicholas J. Napoli

ORCID: 0000-0002-9071-3965
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About
Contact & Profiles
Research Areas
  • Non-Invasive Vital Sign Monitoring
  • EEG and Brain-Computer Interfaces
  • Time Series Analysis and Forecasting
  • Heart Rate Variability and Autonomic Control
  • Anomaly Detection Techniques and Applications
  • Trauma and Emergency Care Studies
  • Emergency and Acute Care Studies
  • Spectroscopy and Chemometric Analyses
  • Advanced Chemical Sensor Technologies
  • Respiratory Support and Mechanisms
  • Balance, Gait, and Falls Prevention
  • Diabetic Foot Ulcer Assessment and Management
  • Hospital Admissions and Outcomes
  • Patient Safety and Medication Errors
  • Abdominal Trauma and Injuries
  • Neuroscience of respiration and sleep
  • Muscle activation and electromyography studies
  • Cardiac Arrest and Resuscitation
  • Healthcare Technology and Patient Monitoring
  • Human-Automation Interaction and Safety
  • ECG Monitoring and Analysis
  • Healthcare Operations and Scheduling Optimization
  • Advanced Statistical Methods and Models
  • Sports Performance and Training
  • Machine Learning and Data Classification

University of Florida
2019-2025

Applied Optimization (United States)
2021-2024

National Institute of Aerospace
2018-2022

Breathe California of Sacramento Emigrant Trails
2022

University of Virginia
2014-2019

Langley Research Center
2017

University of Miami
2014

University of Colorado Denver
1980

Columbia University
1964

10.1016/0030-4220(64)90145-8 article EN Oral Surgery Oral Medicine Oral Pathology 1964-02-01

<sec> <title>BACKGROUND</title> Respiratory impairment is a major concern in amyotrophic lateral sclerosis (ALS), shortening survival and lowering quality of life. One therapy with promise to delay respiratory decline ALS acute intermittent hypoxia (AIH) consisting alternating periods breathing mildly hypoxic (~9-12% O2) normoxic (21% gas. AIH stimulates spinal, serotonin-dependent neuroplasticity rodent models, conferring functional benefits diverse physiological systems without detectable...

10.2196/preprints.76105 preprint EN 2025-04-17

The Commercial Aviation Safety Team found the majority of recent international commercial aviation accidents attributable to loss control inflight involved flight crew airplane state awareness (ASA), and distraction was in all them. Research on attention-related human performance limiting states (AHPLS) such as channelized attention, diverted startle/surprise, confirmation bias, has been recommended a Enhancement (SE) entitled Training for Attention Management. To accomplish detection...

10.2514/6.2017-1135 article EN 2018 AIAA Information Systems-AIAA Infotech @ Aerospace 2017-01-05

Increasing access to urban waterfronts hold much promise for promoting healthy behaviors. While many US cities are revitalising their waterfronts, the health and well-being benefits associated with these design initiatives largely unknown. Tactical interventions (such as parklets pop-ups) short-term projects that experiment gather input on potential changes. To date, effect of individual outcomes has not been measured. This study reports a pilot quasi-experimental which compares real-time...

10.3389/fbuil.2019.00071 article EN cc-by Frontiers in Built Environment 2019-06-14

The characterization of breathing dynamics provides researchers and clinicians the ability to differentiate respiratory compensation, impairment, disease progression, ventilator assistance, onset failure. However, within many sub-fields physiology, we still have challenges identifying changes critical states. We discuss one fundamental modeling how imprecise assumptions decades ago regarding are propagating into our quantitative analysis today, limiting breathing. assumption that is a...

10.3389/fphys.2021.772295 article EN cc-by Frontiers in Physiology 2022-02-21

The most common mechanism of traumatic injury is ground-level fall. objective this study was to understand how patients sustaining falls and their outcomes have evolved. An institutional trauma database used identify adult who suffered a fall were admitted Level I center during two distinct time periods: 1998 2003 (past) 2008 2013 (current). Data on anticoagulant use comorbidities gathered by retrospective chart review treated 2013. Univariable analyses multivariable regression evaluate...

10.1177/000313481808400323 article EN The American Surgeon 2018-03-01

As aviation systems in commercial operations continue to grow complexity, the anomalies exhibited by these become more elaborate and difficult detect. To address challenge of detecting complex anomalies, deep learning models have been used extensively anomaly detection studies, at expense end-user interpretability. Aiming maintain same level interpretability as traditional threshold-exceedance methods, we our development prediction using ordinal patterns their distributions throughout...

10.2514/6.2024-2615 article EN AIAA SCITECH 2022 Forum 2024-01-04

Objective: This study sought to address the disagreement in literature regarding "golden hour" trauma by using Relative Mortality Analysis overcome previous studies' limitations accounting for acuity when evaluating impact of prehospital time on mortality.Methods: The studies that failed support suffered from their efforts account confounding effects patient relationship between and mortality populations. was designed directly these a novel stratification approach, based patients'...

10.1080/10903127.2018.1489021 article EN Prehospital Emergency Care 2018-08-17

Abstract Electroencephalography (EEG) is a method for recording electrical activity, indicative of cortical brain activity from the scalp. EEG has been used to diagnose neurological diseases and characterize impaired cognitive states. When neurons are temporally synchronized, likelihood reach their threshold potential signal propagate next neuron, increases. This phenomenon typically analyzed as spectral intensity increasing summation these firing. Non-linear analysis methods (e.g., entropy)...

10.1038/s41598-020-60354-2 article EN cc-by Scientific Reports 2020-03-03

Normalized cross-correlation template matching is used as a detection method in many scientific domains. To be practical, must scale to large datasets while handling ambiguity, uncertainty, and noisy data. We propose novel approach based on Dempster-Shafer (DS) Theory MapReduce parallelism. DS addresses conflicts between data sources, data, but traditionally serial. However, we use the commutative associative nature of Dempster's Combination Rule perform parallel computation masses...

10.1109/bigcomp.2016.7425804 article EN 2016-01-01

Individualized biometric data are being incorporated into training and competitions by many coaches trainers to provide insights athletic performance physical fitness of their athletes. Currently, tracking software provides with minimal descriptive statistics on the collected data, resulting in limited actionable outcomes. The collection an opportunity understand variables that indicative performance, create predictive models determine appropriate in-game strategies. In order develop these...

10.1109/sieds.2019.8735633 article EN 2019-04-01

End-of-life care and decisions on withdrawal of life-sustaining therapies vary across countries, which may affect the feasibility future multicenter cardiac arrest trials. In Brazil, therapy is reportedly uncommon, allowing natural history postcardiac hypoxic-ischemic brain injury to present itself. We aimed characterize approaches neuroprognostication survivors among physicians in Brazil.Cross-sectional study.Between August 2, 2019, July 31, 2020, we distributed a web-based survey...

10.1097/cce.0000000000000321 article EN Critical Care Explorations 2021-01-01

Improving trauma performance relies on outcome measures to target groups of patients with suboptimal outcomes. However, this is difficult when examining data sets dominated by high probability survival (POS). The W-Score, a standard metric for evaluating performance, disproportionately weights these populations and inaccurately represents effectiveness across the entire patient spectrum. We introduce Relative Mortality Performance Trend (RMPT) Metric (RMM), which provide valuable insight...

10.1080/24725579.2017.1325948 article EN IISE Transactions on Healthcare Systems Engineering 2017-05-04

View Video Presentation: https://doi.org/10.2514/6.2022-3257.vid Despite recent efforts to move away from traditional threshold exceedance detection methods for aircraft state monitoring, modern still rely on safety thresholds communicate pilots the identification of an anomaly in when a is surpassed. Current mainly depend uninterpretable machine learning models learn complex patterns and relationships contained time series data aircraft. Although these are capable identifying known...

10.2514/6.2022-3257 article EN AIAA Aviation 2019 Forum 2022-06-20

Cognitive state detection and its relationship to observable physiologically telemetry has been utilized for many human-machine human-cybernetic applications. This paper aims at understanding addressing if there are unique psychophysiological patterns over time, a ''physiological temporal fingerprint'', that is associated with specific cognitive states. preliminary work involves commercial airline pilots completing experimental benchmark task inductions of three states: 1) Channelized...

10.2514/6.2020-1193 article EN AIAA SCITECH 2022 Forum 2020-01-05

Measurement of trauma center performance presently relies on W-score calculation and comparison to national data sets. A limitation this practice is a skewing the W score, as it determines overall population that often heavily weighted by patients low acuity. The University Virginia relative mortality metric (RMM) was formulated provide higher resolution in identifying areas improvement within subpopulations using traditional Trauma Injury Severity Score methodology. Lactic acidosis has been...

10.1177/000313481608200733 article EN The American Surgeon 2016-07-01

Late Onset Pompe Disease (LOPD) is an incurable, rare progressive genetic disease. It characterized by glycogen build-up, due to mutations in the gene encoding lysosomal enzyme acid alpha glucosidase, throughout muscle and neural regions. This accumulation associated with cell death fiber swelling, eventually leading respiratory insuffciency airway clearance (i.e. cough) deficiency. Impairments effective result from inability clear normal pulmonary volume. Emerging evidence indicates...

10.1152/physiol.2024.39.s1.2055 article EN Physiology 2024-05-01
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