A5035313480- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Dementia and Cognitive Impairment Research
- Cerebral Palsy and Movement Disorders
- Balance, Gait, and Falls Prevention
- Genetic Neurodegenerative Diseases
- Autism Spectrum Disorder Research
- Neurological Disorders and Treatments
- Alzheimer's disease research and treatments
- Stroke Rehabilitation and Recovery
- Infectious Diseases and Tuberculosis
- Parkinson's Disease and Spinal Disorders
- Folate and B Vitamins Research
- Social Issues in Poland
- Botulinum Toxin and Related Neurological Disorders
- Nutritional Studies and Diet
- Diverse Academic Research Studies
- EEG and Brain-Computer Interfaces
- Ginkgo biloba and Cashew Applications
- Nuclear Receptors and Signaling
- Sleep and related disorders
- Mitochondrial Function and Pathology
- Neurological diseases and metabolism
- Health, Work, and Social Studies in Poland
- Neuroscience and Neural Engineering
Medical University of Silesia
2013-2024
Górnośląskie Centrum Medyczne
2016-2023
University of Silesia in Katowice
2011-2022
Little is known about the early stage balance changes in PD. Many clinicians assume that there are no postural issues PD because of failure to identify them on bedside and clinical testing. Here, we quantify moderate compared these values healthy controls (HC) using assessments posturography.We 15 HC with (PD-II; Hoehn Yahr II) (PD-III; H&Y III). Participants performed various tests a standing task force platform. We quantified spatiotemporal parameters center pressure (COP), sample entropy...
Elevated plasma homocysteine (Hcy) concentration is an independent risk factor for cardiovascular disease, and its involvement in endothelial cell dysfunction well established. However, the role of Hcy folate pathogenesis Parkinson's disease (PD) remains controversial.The study was aimed at evaluating relationships between Hcy, vitamin B12, folic acid levels blood cognitive status PD patients with genetic polymorphisms MTHFR (rs1801133: C>T-677C>T, rs1801131: A>C-1298A>C), COMT (rs4680:...
In this study, we aim to assess and examine cognitive functions in Parkinson's Disease patients using EEG recordings, with a central focus on characteristics associated decline. Based neuropsychological evaluation Mini-Mental State Examination, Montreal Cognitive Assessment, Addenbrooke's Examination-III, 98 participants were divided into three groups. All the particpants of study underwent recordings spectral analysis. The results revealed an increase absolute theta power disease dementia...
<b><i>Background:</i></b> The role of white matter hyperintensities (WMH) and homocysteine (Hcy) other vascular risk factors in the pathogenesis Parkinson's disease (PD) dementia (PDD) remains unclear. <b><i>Objective:</i></b> aim study was to assess impact WMH, Hcy biochemical on PDD. <b><i>Methods:</i></b> A total 192 patients with PD 184 age- sex-matched healthy controls were included. semistructured interview used...
Apolipoprotein E gene (APOE) polymorphism is an important determinant for the development of various cardiovascular and neurodegenerative disorders. There have been conflicting reports association APOE with dementia in Parkinson disease (PD).To determine relationship between polymorphisms plasma cholesterol concentration, PD (PDD).Four-year (1999-2002) case-control study.Academic medical center inpatient outpatient movement disorders services. Patients Consecutive white patients same ethnic...
Background: Stroke patients are particularly vulnerable to delirium episodes, but very little is known about its subsequent adverse mental health outcomes. The author’s objective was explore the association between in-hospital and depression, anxiety, anger apathy after stroke. Methods: A total of 750 consecutive with acute stroke or transient ischemic attack, were screened for during hospitalization. Patients underwent evaluation in hospital, 3 12 months post-stroke; apathy, anxiety...
[Purpose] Parkinson's disease is one of the most frequent diseases central nervous system. Thorough knowledge reasons for movement defects may contribute to ability quality life at a good level as far motor abilities are concerned. The aim study was evaluate influence functional rehabilitation on degree intensity symptoms in disease. [Subjects] research carried out people diagnosed with stage III disease, according Hoehn and Yahr scale classification. [Methods] In order establish clinical...
Cognitive impairment is a persistent and increasingly reported symptom of patients with Parkinson's disease (PD), significantly affecting daily functioning quality. This study aims to evaluate the functional connectivity brain network in various severities cognitive decline using quantitative electroencephalography (EEG) analysis.Based on EEG recorded resting state, coherence phase lag index were calculated 108 divided into three groups according their condition: dementia due PD (PD-D), mild...
Phonoholism is the excessive and harmful use of a smartphone. We are now observing this phenomenon among adults more often. Using smartphone for several hours may lead to somatic psychological symptoms, such as headaches depression. The aim study assess prevalence phonoholism association between overuse neuropsychiatric disorders.A total 368 people (70.1% were woman), aged 19 82 years (average age 26.1), took part in an anonymous questionnaire consisting following elements: Hospital Anxiety...
Previous research confirmed association between delirium and subsequent dementia in different clinical settings, but the impact of post-stroke on cognitive functioning is still under-investigated. Therefore, we aimed to assess risk among patients with stroke in-hospital delirium. A total 750 consecutive admitted unit acute or transient ischemic attacks were screened for delirium, during first seven days after admission. At three- twelve-month follow-up, underwent evaluation. The DSM-5...
Parkinson's disease (PD) is a neurodegenerative disease. Due to constantly growing incidence rate and lowering age of PD patients it becoming more serious social problem.The aim this study was determine the effectiveness physiotherapy procedure with depending on their working status.The research carried out 89 people diagnosed IInd stage according Hoehn Yahr classification. They were divided into two groups: professionally non-working. The Unified Disease Rating Scale (UPDRS) used estimate...
Physical activity (PA) is a factor that may have an influence on the symptoms of Parkinson's disease (PD). The aim this study was to identify potential determinants spontaneous PA in PD patient group. A total 134 patients aged 65.2 ± 9.2 years with Hoehn-Yahr scale score ≤4 and Mini Mental State Examination (MMSE) ≥24 were examined. For study's purposes, authors analyzed age, sex, education, history PD, dopaminergic treatment, severity using Unified Disease Rating Scale (UPDRS), scale....
Background and objectives: Motor rehabilitation improves physical mobility quality of life in Parkinson’s disease (PD). As specialized is expensive resource-consuming, there a need for simpler, cost-effective methods. The purpose the study was to determine whether Nordic Walking (NW) training may support management motor disability PD. Materials Methods: Forty patients (median age 64.0 years, range 50–75 years) with idiopathic PD, Hoehn Yahr stages II–III, were randomly assigned NW or...
Clinical phenotypes of familial hypobetalipoproteinemia (FHBL) are related to a number defective apolipoprotein B (APOB) alleles. Fatty liver disease is typical manifestation, but serious neurological symptoms can appear. In this study, genetic analysis the APOB gene and ophthalmological diagnostics were performed for family members with FHBL. Five relatives FHBL, including proband who developed disorders, examined. A sequencing whole coding region gene, flanking intronic regions, was using...
Apathy, a feeling of indifference or general lack interest and motivation to engage in activity, is one the most common neuropsychiatric symptoms Parkinson's disease (PD). The large variation prevalence underlying pathophysiological processes remain unclear due heterogeneous PD populations. purpose this study was identify risk factors for apathy, modification treatment which may be clinically relevant improve quality life caregiver burden patients with disease. Caucasian subjects were...
Parkinson's disease (PD) is a synucleinopathy, which presents dysautonomia, as its common non-motor symptom. Some research suggests the existing interplay between autonomic nervous system dysfunction and glucose metabolism dysregulation in PD.To determine prevalence of metabolic disorders with particular emphasis on patients PD atypical parkinsonism (AP).A retrospective study was performed by analyzing 461 clinical data consecutive diagnosed PD, multiple atrophy (MSA) progressive...
Wstęp: Z wielu schorzeń i zaburzeń układu nerwowego, których swoiste skutki wpływają na możliwość podejmowania różnych form aktywności zawodowej, szczególną uwagę zasługuje choroba Parkinsona (Parkinson's disease -PD).Stanowi ona coraz większy problem społeczny ze względu rosnącą liczbę zachorowań niższy wiek pacjentów.Celem badań było określenie wpływu pracy zawodowej rehabilitacji ruchowej jakość życia osób z PD.Materiał metody: W badaniach uczestniczyło 109 rozpoznaną PD w II stopniu...