- Neurological disorders and treatments
- Peripheral Neuropathies and Disorders
- Parkinson's Disease Mechanisms and Treatments
- Multiple Sclerosis Research Studies
- Hereditary Neurological Disorders
- Botulinum Toxin and Related Neurological Disorders
- Genetic Neurodegenerative Diseases
- Autoimmune Neurological Disorders and Treatments
- Long-Term Effects of COVID-19
- Polish Historical and Cultural Studies
- Myasthenia Gravis and Thymoma
- Migraine and Headache Studies
- Peripheral Nerve Disorders
- Voice and Speech Disorders
- Glycogen Storage Diseases and Myoclonus
- Sympathectomy and Hyperhidrosis Treatments
- Advanced Neuroimaging Techniques and Applications
- Olfactory and Sensory Function Studies
- Systemic Sclerosis and Related Diseases
- Dysphagia Assessment and Management
- Vestibular and auditory disorders
- Neurogenetic and Muscular Disorders Research
- Trigeminal Neuralgia and Treatments
- Acute Ischemic Stroke Management
- Child Nutrition and Feeding Issues
Wroclaw Medical University
2016-2025
Octapharma (Austria)
2021-2023
Boston University
2022
Boston Medical Center
2022
Hospital de Egas Moniz
2022
University of Thessaly
2022
University of Wrocław
2011-2021
Weatherford College
2021
Neurology, Inc
2013-2021
Szpital Kliniczny Nr 1 we Wrocławiu
2019
Alpha-synucleinopathy constituting a characteristic feature of Parkinson's disease (PD) occurs at all levels the brain-gut axis including enteric nervous system (ENS). Lesions in ENS may be connected with gut inflammation, increased intestinal permeability and dysmotility contributing to pathogenesis PD its gastrointestinal manifestations. To evaluate fecal calprotectin zonulin as biomarkers inflammation barrier dysfunction patients. Quantitative evaluation was performed by ELISA tests 35...
The Migraine in Poland study is the first large scale nationwide cross-sectional online survey of symptoms, approaches to management, treatment patterns, quality life, and sociodemographic characteristics Polish migraine patients' cohort, conducted from August 2021 June 2022.A was designed based on American Prevalence Prevention (AMPP) Study. Participants were recruited through broad advertisement various channels. included questions allowing for diagnosis without aura (MwoA) third edition...
Abstract Background: Based on Davis's law, greater tonus of the muscle belly in individuals with Parkinson's disease can create tension tendon, leading to structural adjustment and an increase tendon stiffness. Our study aimed separately assess passive stiffness medicated patients disease, using myotonometry. Methods: We tested 12 healthy matched controls. Passive was estimated by myotonometry, electromyography, mechanomyography relaxed biceps triceps brachii muscles. Results: Compared...
Elevated plasma homocysteine (Hcy) concentration is an independent risk factor for cardiovascular disease, and its involvement in endothelial cell dysfunction well established. However, the role of Hcy folate pathogenesis Parkinson's disease (PD) remains controversial.The study was aimed at evaluating relationships between Hcy, vitamin B12, folic acid levels blood cognitive status PD patients with genetic polymorphisms MTHFR (rs1801133: C>T-677C>T, rs1801131: A>C-1298A>C), COMT (rs4680:...
Background: This study examined the generalized effects of cycle ergometer aerobic interval training (AIT) on psychomotor behaviors in individuals with Parkinson’s disease (PD), including bimanual motor control, cognitive function, and neurological non-motor parkinsonian signs. Methods: Twenty mild to moderate PD patients were randomly allocated following groups: (1) trained group (PD-TR, n = 10), which besides receiving usual care, underwent an 8-week intensity AIT program; or (2) control...
Introduction. The aim of this study was to report the course and outcome SARS-CoV-2 infection in multiple sclerosis (MS) patients treated with disease-modifying therapies (DMTs) Poland. A major concern for neurologists worldwide is MS different DMTs. Although initial studies do not suggest an unfavourable group patients, data limited. Materials methods. This included 396 DMTs confirmed from 28 Polish centres. Information concerning patient demographics, comorbidities, clinical MS, current...
The genesis of headache in coronavirus disease 2019 (COVID-19) is currently unclear and the multitude symptoms often further hinders locating source pain. Interestingly, many subjects with COVID-19 have acute rhinosinusitis. relation between nasal SARS-CoV-2 infection remains unknown.This bi-center longitudinal study evaluated consecutive patients participating practices. first assessment was performed during initial consultation after confirmation. That followed up by a second median 9...
We aimed to investigate the extent of alterations in pro/antioxidant balance blood patients with relapsing-remitting multiple sclerosis (RRMS) relation drug-modified therapy, gender, disability score, and disease duration. 161 (67 men 94 women, aged 24-69 years, median 43.0) 29 healthy individuals (9 20 25-68 41.0) were included study. measured activity superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) as well concentration interleukin-6 (IL-6), lipid peroxidation...
Abstract Background Spinal adhesive arachnoiditis is a chronic inflammatory process of the leptomeninges and intrathecal neural elements. The possible causes are: infections, injuries spinal cord, surgical procedures administration therapeutic substances or contrast. Case presentation We present case 56-old woman with muscular atrophy type 3 who developed severe back pain in lumbosacral region after fifth dose nusinersen given intrathecally. Magnetic resonance spine showed arachnoiditis. She...
Cranial autonomic symptoms (CASs) include lacrimation, conjunctival injection, rhinorrhea, nasal congestion, facial flushing or sweating, ptosis, and myosis. These may be associated with trigeminal cephalalgias (TACs) migraine.
<b><i>Background:</i></b> The role of white matter hyperintensities (WMH) and homocysteine (Hcy) other vascular risk factors in the pathogenesis Parkinson's disease (PD) dementia (PDD) remains unclear. <b><i>Objective:</i></b> aim study was to assess impact WMH, Hcy biochemical on PDD. <b><i>Methods:</i></b> A total 192 patients with PD 184 age- sex-matched healthy controls were included. semistructured interview used...
Abstract Intravenous immunoglobulin treatment for chronic inflammatory demyelinating polyneuropathy usually starts with a 2.0 g/kg induction dose followed by 1.0 maintenance doses every 3 weeks. No dose-ranging studies intravenous therapy have been published. The Progress in Chronic Inflammatory Demyelinating (ProCID) study was prospective, double-blind, randomized, parallel-group, multicentre, phase III investigating the efficacy and safety of 10% liquid (Panzyga®) patients active...
Holmes tremor (HT) is a combination of rest, postural and action tremor. A parallel dysfunction cerebello-thalamic nigrostriatal pathways seems necessary to produce this kind We present the clinical neuroimaging study verifying that hypothesis.A total 10 patients: five male, female, fulfilling consensus criteria were included. Demographic, data (MRI = 9; CT 1, SPECT with use 123-I-FP CIT: DaTSCAN in six patients assess presynaptic dopaminergic system involvement, indices asymmetry for ligand...
Background.The effect multiple sclerosis (MS) has on the social functioning and integration of patients been recently considered as an important factor disease. Objectives.To assess participation MS with regard to demographic disease-related variables.Material methods.The study comprised 201 patients: 140 women, 61 men, aged 24-69 years.The World Health Organization Disability Assessment Schedule (WHODAS 2.0) was applied aspects Beck Depression Inventory (BDI) evaluate level...
Abstract Thyroid dysfunction is very often accompanied by cognitive and affective disorders. The frequency of these disorders in patients with compensated Hashimoto’s thyroiditis (HT) unknown. aim the present study was to evaluate brain euthyroid HT means event-related potentials (ERP) magnetic resonance spectroscopy (MRS) correlate it function. 68 (59 female, 9 male) 45 healthy controls were included study. All underwent ERP including an analysis N200 P300 response parameters. MRS voxels...
The effect of the coronavirus disease 2019 (COVID-19) on nervous system remains undefined. Some studies have shown that headache is one most common symptoms and often first neurological symptom in patients with confirmed infection. There are only a few reports concerning effects COVID-19 course migraine. This article investigates three female prolonged history migraine, which atypical phenomenology migraine attacks were observed during