A5087440550- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Polyomavirus and related diseases
- Autoimmune and Inflammatory Disorders Research
- Liver Diseases and Immunity
- Systemic Lupus Erythematosus Research
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Vestibular and auditory disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Systemic Sclerosis and Related Diseases
- Autoimmune Bullous Skin Diseases
- Ocular Diseases and Behçet’s Syndrome
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Thyroid Cancer Diagnosis and Treatment
- Liver Disease and Transplantation
- Amyotrophic Lateral Sclerosis Research
- Fungal Plant Pathogen Control
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Endoplasmic Reticulum Stress and Disease
- Single-cell and spatial transcriptomics
- Cerebral Venous Sinus Thrombosis
- HER2/EGFR in Cancer Research
Cliniques Universitaires Saint-Luc
2015-2025
UCLouvain
2017-2023
Centre Hospitalier Universitaire Amiens-Picardie
2011
Abstract Background Evidence of immune-mediated neurological syndromes associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is limited. We therefore investigated clinical, serological and CSF features disease 2019 (COVID-19) patients manifestations. Methods Consecutive COVID-19 manifestations other than isolated anosmia and/or non-severe headache, no previous or psychiatric disorders were prospectively included. Neurological examination was performed in...
Chronic active lesions (CAL) in multiple sclerosis (MS) have been observed even patients taking high-efficacy disease-modifying therapy, including B-cell depletion. Given that CAL are a major determinant of clinical progression, progression independent relapse activity (PIRA), understanding the predicted and real-world effects targeting specific lymphocyte populations is critical for designing next-generation treatments to mitigate chronic inflammation MS.We analyzed published single-cell...
Mobility limitations are frequent in patients with multiple sclerosis (MS), and could already be present so-called mild neurological disability (Expanded Disability Status Scale≤4). Assessing mobility these is therefore of paramount importance. Timed Up-and-Go Test (TUG) 2-Minute Walk (2MWT) two clinically feasible tests which reliability responsiveness unknown among patients. Whether fatigue, the number one symptom patients, linked to remains unknown.The aim this study was explore...
This paper deals with thyroid disease that can occur after treatment alemtuzumab (humanized monoclonal anti-CD52) for relapsing-remitting multiple sclerosis (MS). The 5-year incidence of adverse events in phase 3 clinical trials is up to 40.7%. In most cases, the dysfunction mild and easily manageable only few serious have been reported. need patient education on risk dysfunction, as well regular biochemical function screening described. However, practical guidance case abnormal...
Fatigue is frequent and disabling in persons with multiple sclerosis (pwMS) mild neurological disability. These patients also have impaired physical fitness. Whether mildly disabled pwMS are deconditioned, this deconditioning linked to fatigue, remains unknown. Our aim determine the fitness of study its relationship perceived fatigue link other parameters. Twenty (14 women; mean age: 45.5 years) disability (Expanded Disability Status Scale 0-4) underwent a 2-min walking test, Timed Up-and-Go...
Background Telerehabilitation is a promising approach for patients with multiple sclerosis (MS), but uncertainties regarding patients' access and preferences remain. Aim To investigate the to telecommunication technologies rehabilitation services of MS, their willingness use these rehabilitation. Design Cross-sectional survey. Setting Outpatient neurological facility. Population Patients MS. Methods MS attending consultations in Neurology department were asked fill paper questionnaire. This...
Background: Chronic active lesions (CAL) in multiple sclerosis (MS) have been observed even patients taking high-efficacy disease-modifying therapy, including B-cell depletion. Given that CAL are a major determinant of clinical progression, progression independent relapse activity (PIRA), understanding the predicted and real-world effects targeting specific lymphocyte populations is critical for designing next-generation treatments to mitigate chronic inflammation MS.Methods: We analyzed...
Progressive multifocal leukoencephalopathy (PML) may develop in follicular lymphoma patients treated with bendamustine-rituximab. In this report, treatment pembrolizumab successfully inhibited the clinical progression of PML by promoting radiologically demonstrated immune restoration inflammatory syndrome (IRIS), allowing complete clearance virus. These findings further support use special consideration for potential occurrence IRIS.
Abstract Background One of the challenges when caring for children admitted acute liver failure (ALF) is to quickly identify those who will improve spontaneously and whom transplantation (LT) only therapeutic option. Methods Retrospective study review our experience, mortality risk factors update LT criteria in case paediatric ALF. Results 111 were between March 1989 May 2021 (mean age 59.1 months). 28 never met criteria; 17 had contraindication LT; 66 registered on waitlist. 14 these...