A5005905613- Metal-Organic Frameworks: Synthesis and Applications
- Ferroelectric and Piezoelectric Materials
- Microwave Dielectric Ceramics Synthesis
- Polyoxometalates: Synthesis and Applications
- Magnetism in coordination complexes
- Tea Polyphenols and Effects
- Acupuncture Treatment Research Studies
- Dielectric properties of ceramics
- Heavy metals in environment
- Postharvest Quality and Shelf Life Management
- Plant Physiology and Cultivation Studies
- Plant Stress Responses and Tolerance
- Phytochemicals and Antioxidant Activities
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced Nanomaterials in Catalysis
- Neurological Disease Mechanisms and Treatments
- Mercury impact and mitigation studies
- Geochemistry and Elemental Analysis
- Food Quality and Safety Studies
- Endometrial and Cervical Cancer Treatments
- Plant Molecular Biology Research
- Metal complexes synthesis and properties
- Geochemistry and Geologic Mapping
- Plant Gene Expression Analysis
China Agricultural University
2022-2024
First Affiliated Hospital of Anhui Medical University
2024
Anhui Medical University
2014-2024
China Metallurgical Geology Bureau
2022-2024
Affiliated Hospital of Qingdao University
2021-2024
Qingdao University
2021-2024
Nanjing Medical University
2009-2023
Zhejiang University
2019-2023
Nanjing Drum Tower Hospital
2021-2023
Harbin Medical University
2010-2023
Abstract Malate impacts fruit acidity and plays a vital role in stress tolerance. accumulation is induced by salinity various plants as metabolite coping with this stress. However, the exact molecular mechanism responsible for salinity-induced malate remains unclear. Here, we determined that treatment induces pear (Pyrus spp.) fruit, calli, plantlets compared to control. Genetic biochemical analyses established key roles of PpWRKY44 ABRE-BINDING FACTOR3 (PpABF3) transcription factors...
Building a virtual cell requires comprehensive understanding of protein network dynamics which necessitates large-scale perturbation proteome data and intelligent computational models learned from the corpus. Here, we generate dataset over 38 million perturbed measurements in breast cancer lines develop neural ordinary differential equation-based foundation model, namely ProteinTalks. During pretraining, ProteinTalks gains fundamental cellular dynamics. Our model encodes networks exhibits...
Ethylene response factor (ERF) has been widely studied in regulating fruit ripening tomato, apple, banana and kiwifruit, but little is known pear. In this study 1-methylcyclopropene (1-MCP) treatment, an inhibitor of ethylene perception, was conducted at approximately 30 days before harvest to delay a climacteric white pear cultivar Yali. Transcriptome libraries were constructed sequenced pre-ripening, ripening, 1-MCP treated fruits. Data analysis showed that 73 candidate genes related...
Albino became a novel kind of tea cultivar in China recently. In this study, transcriptome and whole-genome bisulfite sequencing (WGBS) were employed to investigate the shading effects on leaf color conversion biosynthesis three major secondary metabolites albino "Yujinxiang". The increased chlorophyll level was likely cause for shaded greening from young pale or yellow leaf. comparison with control, total catechin group significantly decreased abundance caffeine markedly increased, while...
OBJECTIVE The comparative neuroprotective effects of different antidiabetes drugs have not been characterized in randomized controlled trials. Here, we investigated the therapeutic liraglutide, dapagliflozin, or acarbose treatment on brain functional alterations and cognitive changes patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Thirty-six diabetes inadequately metformin monotherapy were to receive for 16 weeks. Brain MRI (fMRI) scan a battery assessments evaluated pre-...
Recently, an increasing number of studies have suggested that mTOR plays a critical role in the regulation tumor cell motility, invasion and cancer metastasis. However, little is known about signaling mechanisms regulating epithelial–mesenchymal transition (EMT) prostate cancer. In this study, we found expression levels Raptor Rictor tissues were elevated, which may suggest pathways are associated with progression Inhibition mTORC1 or mTORC2 by knock down Rictor, respectively, migration...
A broad spectrum of rhizosphere bacteria and fungi were shown to play a central role for health, fitness productivity their host plants. However, implications metabolism on microbiota assembly in the phyllosphere potential consequences holobiont functioning sparsely addressed. Previous observations indicated that tea plants might reduce disease occurrence various forests located proximity; underlying mechanisms remained elusive.
Abstract L-Theanine is a crucial secondary metabolite in tea and positively determines the potential quality health benefits of products. Previous work found that content L-theanine decreased during withering process, although specific mechanism still unknown. Here, weighted gene co-expression network analysis (WGCNA) was performed based on transcriptome data obtained previously. The key hydrolysis CsPDX2.1 metabolism seven candidate transcription factors were screened out. Among these...
Assembly and co-occurrence of the host co-evolved microbiota are essential ecological evolutionary processes, which is not only crucial for managing individual plant fitness but also function. However, understanding microbiome assembly in higher plants well understood. The tea was shown to contribute forest due assembled phyllosphere; landscape its potential implication on phyllosphere homestasis still remains untangled.
Copy number variations (CNVs), a major source of human genetic polymorphism, have been suggested to an important role in susceptibility common diseases such as cancer, immune and neurological disorders. Nasopharyngeal carcinoma (NPC) is multifactorial tumor closely associated with background male preponderance over female (3:1). Previous genome-wide association studies identified single-nucleotide polymorphisms (SNPs) that are NPC susceptibility. Here, we sought explore the possible CNVs...
Berry fruit juice, which is represented by blueberry and cranberry has become increasingly popular due to its reported nutritional health benefits. However, in markets, adulteration of berry juice with cheaper substitutes frequent. In the present study, a metabolomic approach for authentication juices liquid chromatography coupled quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) was established. The global characterization metabolome information dependent acquisition directed...
A non-invasive method for detecting glucose is pursued by millions of diabetic patients to improve their personal management blood glucose. In this work, a novel CuO nanoparticles (NPs) decorated polycaprolactone@polypyrrole fibers modified indium-tin oxide (denoted as CuO/PCL@PPy/ITO) electrode has been fabricated electrospinning combined with the electrodeposition non-enzymatic detection in saliva fluid. The electrospun composite exhibit high sensitivity detection. synergistic effect...
Plant hormones play an important role in the chemical metabolism of postharvest plants. However, alterations plant tea and their potential modulation quality-related metabolites are unknown. In this study, dynamic abscisic acid (ABA), salicylic (SA), jasmonic (JA), critical metabolites, such as catechins, theanine, caffeine, leaves were analyzed during withering from 0 to 24 h. It was found that ABA content increased 9 h but decreased thereafter, JA continuously increased, SA showed no...