Xuezhu Zhang

ORCID: 0000-0002-3016-1556
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Neurological Disease Mechanisms and Treatments
  • Acupuncture Treatment Research Studies
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological Disorders and Treatments
  • Healthcare and Venom Research
  • Second Language Acquisition and Learning
  • Mitochondrial Function and Pathology
  • Gastrointestinal motility and disorders
  • Stress Responses and Cortisol
  • Heat shock proteins research
  • Atherosclerosis and Cardiovascular Diseases
  • Drug Solubulity and Delivery Systems
  • Analytical Chemistry and Chromatography
  • Complementary and Alternative Medicine Studies
  • Bone Metabolism and Diseases
  • Analytical Chemistry and Sensors
  • Bone health and osteoporosis research
  • EFL/ESL Teaching and Learning
  • Traditional Chinese Medicine Studies
  • Medical Imaging Techniques and Applications
  • Dye analysis and toxicity
  • Cancer Genomics and Diagnostics
  • Barrier Structure and Function Studies
  • Axon Guidance and Neuronal Signaling

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2016-2025

General Administration of Quality Supervision, Inspection and Quarantine
2024

Xinjiang Technical Institute of Physics & Chemistry
2023

Xinjiang Academy of Forestry
2023

Xinjiang University
2023

Xinjiang Institute of Engineering
2023

Hunan University of Science and Technology
2005-2020

Tianjin University of Traditional Chinese Medicine
2004-2019

China Association of Acupuncture-Moxibustion
2017

Shenyang Pharmaceutical University
2013-2014

Alzheimer's disease (AD) is the most common cause of dementia. However, none medical treatment can stop or reverse underlying neurodegenerative AD at present. Acupuncture has attracted more and attention in recent years due to its efficacy very few side effects. Lately, a systematic review thought that evidence on effectiveness acupuncture improving cognitive function patients was not powerful enough. Therefore, aim this study explore safety with mild moderate AD. This randomized,...

10.1186/s12906-017-2064-x article EN cc-by BMC Complementary and Alternative Medicine 2017-12-01

<title>Abstract</title> Background Neurons are the fundamental structural and functional units of nervous system, serving as core cells for information transmission regulation. They closely associated with various neurological diseases. Recent studies have shown significant advancements in research on ferroptosis neurons; however, there has been a lack bibliometric analysis this field. This study aims to provide comprehensive overview knowledge structure related neurons through methods,...

10.21203/rs.3.rs-5653722/v1 preprint EN cc-by Research Square (Research Square) 2025-01-17

To investigate the effects and potential mechanism of electroacupuncture intervention on expressions Angiotensin II its receptors-mediated signaling pathway in experimentally induced cerebral ischemia. Totally 126 male Wistar rats were randomly divided into control group, model group EA group. The latter two further ten subgroups (n = 6) following Middle Cerebral Artery Occlusion (MCAO). Changes regional blood flow (rCBF) receptors (AT1R, AT2R), as well effector proteins phosphatidyl...

10.1186/1472-6882-14-441 article EN cc-by BMC Complementary and Alternative Medicine 2014-11-11

Objectives To examine whether acupuncture could improve cognitive deficits and reduce the loss of neurons in mice models ageing. Methods Male 7.5-month-old senescence-accelerated mouse prone 8 (SAMP8) age-matched senescence-resistant inbred strains 1 (SAMR1) were divided into four groups (n=15 per group): SAMP8 group (Pa), non-acupuncture point control (Pn), (Pc) SAMR1 normal (Rc). The behaviours examined by Morris water maze test neuron density hippocampus was estimated optical fractionator...

10.1136/acupmed-2012-010180 article EN Acupuncture in Medicine 2012-09-13

The aim of this study is to analyze the effects acupuncture on peripheral immune function, inflammation, and cognitive impairment in vascular dementia (VD) rats.In study, 2-month-old healthy male Wistar rats (260-280 g) were assigned groups as follows: normal group (Gn, n = 10), sham-operated (Gs, operated (Go, 45). Go was established by permanent, bilateral common carotid artery occlusion (BCCAO). Two months after operation, screened hidden platform trial with dysfunction further randomly...

10.3389/fnagi.2021.706834 article EN cc-by Frontiers in Aging Neuroscience 2021-07-19

Acupuncture may improve gastrointestinal symptoms in patients with various disorders, but its efficacy diabetic gastroparesis is unclear.To evaluate the short-term effects of acupuncture on gastric emptying and gastroparesis.In a single-blind controlled crossover trial, 25 were randomly assigned to undergo 1 week real (RA) treatment followed by sham (SA) treatment, or vice versa, washout month between. Before after each intervention, retention, Gastroparesis Cardinal Symptom Index (GCSI),...

10.1136/acupmed-2014-010670 article EN Acupuncture in Medicine 2015-02-18

Stimuli-responsive drug release nanoparticles are of particular interest due to their enhanced effects and reduced systemic toxicities in the area cancer therapeutics. The effect these on cellular microenvironment has not yet been clearly defined. In this context, redox-responsive were synthesized with disulfide-containing linkages. These depleted GSH level modulated redox more oxidizing conditions. resulting drug-encapsulated showed improved cytotoxicity, apoptosis, invasion inhibition...

10.1039/c6tb00847j article EN Journal of Materials Chemistry B 2016-01-01

ObjectiveThe present study was developed to explore the impact of acupuncture on Th17/Treg balance in brain and periphery associated changes cognitive deficits a rat model vascular dementia (VD).MethodsMale Wistar rats (8 weeks old) were randomly assigned sham-operated (Gs, n = 10), operation (n 30) groups. A VD established for all group via permanent bilateral occlusion common carotid artery. Behavioral screening these conducted hidden platform trial at 2 months post-operation. These then...

10.1016/j.heliyon.2023.e13346 article EN cc-by-nc-nd Heliyon 2023-01-31

BACKGROUND Alzheimer's disease (AD) is an age-associated neurodegenerative disorder. This study aimed to investigate effects of acupuncture administration on cognitive function and associated mechanisms. MATERIAL AND METHODS Senescence-accelerated prone 8 (SAM-P8) mice were randomly divided into 3 groups: the SAM-P8 group (P8-CN), administrating with (P8-Acup) group, without (P8-Sham) group. Morris water maze test was conducted evaluate functions (memory learning ability). PDK1, nPKC, Rac1...

10.12659/msm.913858 article EN Medical Science Monitor 2019-06-01

&lt;i&gt;Background/Objective:&lt;/i&gt; The effect of acupuncture on the changes in histomorphometric and mechanical properties femurs senescence-accelerated mice strain P6 (SAMP6) was evaluated this work. &lt;i&gt;Methods:&lt;/i&gt; Six-month-old male SAMP6 SAMR1 were allocated to 1 4 groups: control group (Pc), non-acupoint (Pn), (Pa) (Rc). Pa acupunctured at Shenshu point (BL23) once daily for 8 weeks. Two non-acupoints hypochondria needled Pn group. Mice other 2 groups grasped using...

10.1159/000214845 article EN Gerontology 2009-01-01

Transmembrane and intracellular signal transduction of G protein is closely related to the pathophysiology Alzheimer's disease (AD).To explore effects Sanjiao acupuncture on pathways in pathogenesis AD.36 senescence-accelerated (SAM) prone 8 mice were divided into three groups that remained untreated (SAMP8, n=12) or received (SAMP8+SA, control (SAMP8+CA, n=12). An additional group SAM resistant 1 was included (SAMR1 group, Morris water maze tests used investigate learning memory abilities....

10.1136/acupmed-2016-011139 article EN Acupuncture in Medicine 2017-04-28

To determine the clinical efficacy and safety of electro-scalp acupuncture in treatment patients with acute ischemic stroke. Totally 74 stroke were enrolled divided into either body (Control) or (ESA) groups according to randomized controlled principle. The control group given once daily for 28 d, whereas except acupuncture, was additional ESA group. Neurological deficits, everyday motor function muscle strength evaluated at baseline 28th d by NIH Stroke Scale (NIHSS), Fugl-Meyer Assessment...

10.1016/j.jtcm.2018.02.012 article EN other-oa Deleted Journal 2018-02-01

In order to investigate the pathogenic targets and associated biological process of Alzheimer's disease in present study, mRNA expression profiles (GSE28146) microRNA (miRNA) (GSE16759) were downloaded from Gene Expression Omnibus database. GSE28146, eight control samples, samples comprising seven incipient, moderate, severe included. The Affy package R was used for background correction normalization raw microarray data. differentially expressed genes (DEGs) miRNAs identified using Limma...

10.3892/mmr.2016.5828 article EN Molecular Medicine Reports 2016-10-12
Coming Soon ...